Gene Page: TRIM27

Summary
GeneID  5987
Symbol  TRIM27
Synonyms  RFP|RNF76
Description  tripartite motif-containing 27
See related  HGNC:9975|MIM:602165|Ensembl:ENSG00000204713|HPRD:15996|
Locus tag  DAAP-182E11.3
Gene type  protein-coding
Map location  6p22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PDLIM30.520.43
PECI0.500.44
CD990.500.35
DBI0.490.43
NUP370.470.35
SNRPG0.460.31
TEX90.460.21
EFNA40.450.35
CLIC10.450.34
RAB320.450.30
Top 10 negatively co-expressed genes
NDRG1-0.35-0.40
SLCO3A1-0.35-0.37
AC016910.1-0.35-0.39
DOCK9-0.35-0.34
C1orf115-0.34-0.39
KIF16B-0.34-0.30
SPTBN2-0.33-0.34
RHOU-0.33-0.37
SPTBN1-0.33-0.32
DUSP7-0.33-0.35
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004714transmembrane receptor protein tyrosine kinase activityTASneurite (GO term level: 8)3078962 
GO:0003677DNA bindingIEA-
GO:0005515protein bindingIPI9570750 |15837424 
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingTAS3380101 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000122negative regulation of transcription from RNA polymerase II promoterIDA10976108 
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
GO:0007283spermatogenesisTAS3380101 
GO:0008283cell proliferationTAS2734021 
GO:0045814negative regulation of gene expression, epigeneticIDA10976108 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005624membrane fractionTAS3078962 
GO:0005634nucleusIEA-
GO:0005654nucleoplasmIDA10976108 
GO:0005737cytoplasmIEA-
GO:0005887integral to plasma membraneTAS3078962 
GO:0031965nuclear membraneIDA10976108 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BEGAINKIAA1446brain-enriched guanylate kinase-associated homolog (rat)Two-hybridBioGRID16189514 
CHD4DKFZp686E06161 | Mi-2b | Mi2-BETAchromodomain helicase DNA binding protein 4-HPRD14530259 
DNMT1AIM | CXXC9 | DNMT | FLJ16293 | MCMT | MGC104992DNA (cytosine-5-)-methyltransferase 1Two-hybridBioGRID16169070 
EIF3EEIF3-P48 | EIF3S6 | INT6 | eIF3-p46eukaryotic translation initiation factor 3, subunit E-HPRD10504338 
EPC1DKFZp781P2312 | Epl1enhancer of polycomb homolog 1 (Drosophila)-HPRD10976108 
FBF1Alb | FBF-1 | FLJ00103Fas (TNFRSF6) binding factor 1Two-hybridBioGRID16189514 
FXYD6-FXYD domain containing ion transport regulator 6Two-hybridBioGRID16169070 
HDAC1DKFZp686H12203 | GON-10 | HD1 | RPD3 | RPD3L1histone deacetylase 1-HPRD14530259 
MAGEA11MAGE-11 | MAGE11 | MAGEA-11 | MGC10511melanoma antigen family A, 11Two-hybridBioGRID16189514 
MCOLN1ML4 | MLIV | MST080 | MSTP080 | TRP-ML1 | TRPM-L1 | TRPML1mucolipin 1Two-hybridBioGRID16169070 
PMLMYL | PP8675 | RNF71 | TRIM19promyelocytic leukemia-HPRD,BioGRID9570750 
PRAM1MGC39864 | PRAM-1PML-RARA regulated adaptor molecule 1Affinity Capture-Western
Two-hybrid		BioGRID9570750 
TRIM11BIA1 | RNF92tripartite motif-containing 11-HPRD,BioGRID11331580 
TRIM23ARD1 | ARFD1 | RNF46tripartite motif-containing 23-HPRD,BioGRID11331580 
TRIM27RFP | RNF76tripartite motif-containing 27Two-hybridBioGRID11331580 
TRIM29ATDC | FLJ36085tripartite motif-containing 29-HPRD,BioGRID11331580 
TRIM32BBS11 | HT2A | LGMD2H | TATIPtripartite motif-containing 32-HPRD,BioGRID11331580 
ZBTB16PLZF | ZNF145zinc finger and BTB domain containing 16Two-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
CASORELLI_APL_SECONDARY_VS_DE_NOVO_UP 3925All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
RIZ_ERYTHROID_DIFFERENTIATION 7751All SZGR genes in this pathway
SCHEIDEREIT_IKK_INTERACTING_PROTEINS 5845All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP 176111All SZGR genes in this pathway
TOMLINS_PROSTATE_CANCER_UP 4027All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN 225163All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
HOWLIN_CITED1_TARGETS_2_UP 1710All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G 17196All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BAKKER_FOXO3_TARGETS_DN 187109All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
PECE_MAMMARY_STEM_CELL_DN 14688All SZGR genes in this pathway


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