Gene Page: AKTIP

Summary
GeneID  64400
Symbol  AKTIP
Synonyms  FT1|FTS
Description  AKT interacting protein
See related  HGNC:16710|MIM:608483|Ensembl:ENSG00000166971|HPRD:07467|
Locus tag  -
Gene type  protein-coding
Map location  16q12.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0078 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI14749367 
GO:0019787small conjugating protein ligase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001934positive regulation of protein amino acid phosphorylationIDA14749367 
GO:0032092positive regulation of protein bindingIDA14749367 
GO:0051246regulation of protein metabolic processIEA-
GO:0043687post-translational protein modificationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneIDA14749367 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AKT1AKT | MGC99656 | PKB | PKB-ALPHA | PRKBA | RAC | RAC-ALPHAv-akt murine thymoma viral oncogene homolog 1-HPRD,BioGRID14749367 
ASS1ASS | CTLN1argininosuccinate synthetase 1Two-hybridBioGRID16169070 
C10orf2ATXN8 | FLJ21832 | IOSCA | PEO | PEO1 | PEOA3 | SANDO | SCA8 | TWINLchromosome 10 open reading frame 2Two-hybridBioGRID16169070 
CTBP2-C-terminal binding protein 2Two-hybridBioGRID16189514 
DCTN1DAP-150 | DP-150 | HMN7B | P135dynactin 1 (p150, glued homolog, Drosophila)Affinity Capture-MSBioGRID17353931 
EXOC72-5-3p | DKFZp686J04253 | EX070 | EXO70 | EXOC1 | Exo70p | FLJ40965 | FLJ46415 | YJL085Wexocyst complex component 7Two-hybridBioGRID16169070 
GTF3C1DKFZp686A111 | TFIIIC | TFIIIC220 | TFIIICalphageneral transcription factor IIIC, polypeptide 1, alpha 220kDaTwo-hybridBioGRID16169070 
HDLBPFLJ16432 | HBP | PRO2900 | VGLhigh density lipoprotein binding proteinAffinity Capture-MSBioGRID17353931 
HOOK1HK1 | MGC10642hook homolog 1 (Drosophila)Affinity Capture-MSBioGRID17353931 
HOOK2FLJ26218 | HK2hook homolog 2 (Drosophila)Two-hybridBioGRID16189514 
IARSFLJ20736 | IARS1 | ILRS | PRO0785isoleucyl-tRNA synthetaseAffinity Capture-MSBioGRID17353931 
IMMTDKFZp779P1653 | HMP | MGC111146 | P87 | P87/89 | P89 | PIG4 | PIG52inner membrane protein, mitochondrial (mitofilin)Two-hybridBioGRID16169070 
KIAA1377-KIAA1377Two-hybridBioGRID16169070 
PDPK1MGC20087 | MGC35290 | PDK1 | PRO04613-phosphoinositide dependent protein kinase-1-HPRD14749367 
PDS5ADKFZp686B19246 | FLJ41012 | KIAA0648 | MGC131948 | MGC161503 | PIG54 | SCC-112PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)Affinity Capture-MSBioGRID17353931 
POLA2FLJ21662 | FLJ37250polymerase (DNA directed), alpha 2 (70kD subunit)Two-hybridBioGRID16169070 
RPA1HSSB | REPA1 | RF-A | RP-A | RPA70replication protein A1, 70kDaTwo-hybridBioGRID16169070 
TIMM50MGC102733 | TIM50 | TIM50Ltranslocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)Affinity Capture-MSBioGRID17353931 
UTP14AKIAA0266 | NY-CO-16 | SDCCAG16 | dJ537K23.3UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_6HR_DN 167100All SZGR genes in this pathway
COLDREN_GEFITINIB_RESISTANCE_DN 230115All SZGR genes in this pathway
ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_UP 6344All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_DN 4831All SZGR genes in this pathway
KIM_MYCN_AMPLIFICATION_TARGETS_DN 10359All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP 424268All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
GUO_HEX_TARGETS_UP 8154All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
YAMAZAKI_TCEB3_TARGETS_DN 215132All SZGR genes in this pathway
BURTON_ADIPOGENESIS_11 5740All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 482296All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP 578341All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_DN 12081All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP 439257All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9 7645All SZGR genes in this pathway
IVANOVSKA_MIR106B_TARGETS 9056All SZGR genes in this pathway
LINSLEY_MIR16_TARGETS 206127All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
KUMAR_PATHOGEN_LOAD_BY_MACROPHAGES 275155All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1015895951Ahsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-1445895951Ahsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-17-5p/20/93.mr/106/519.d2531m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-451627633m8hsa-miR-451brainAAACCGUUACCAUUACUGAGUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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