Gene Page: SKIV2L

Summary
GeneID  6499
Symbol  SKIV2L
Synonyms  170A|DDX13|HLP|SKI2|SKI2W|SKIV2
Description  superkiller viralicidic activity 2-like (S. cerevisiae)
See related  HGNC:10898|MIM:600478|Ensembl:ENSG00000204351|HPRD:02724|
Locus tag  XXbac-BPG116M5.1
Gene type  protein-coding
Map location  6p21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TMEM184B0.860.87
ACO20.850.85
GM2A0.840.82
IPO130.840.85
KLHL210.830.83
ALAD0.830.84
TMEM1890.820.81
AATK0.820.79
PDK20.820.80
PYCR20.820.81
Top 10 negatively co-expressed genes
C9orf46-0.51-0.55
RPS3AP47-0.48-0.50
RPL31-0.47-0.51
RPL13AP22-0.47-0.67
FAM36A-0.47-0.46
RPL24-0.45-0.49
RBMX2-0.45-0.48
FAM159B-0.45-0.69
EXOSC8-0.45-0.46
RP11-1134I14.1-0.45-0.51
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003676nucleic acid bindingIEA-
GO:0003723RNA bindingIEA-
GO:0004004ATP-dependent RNA helicase activityTAS7610041 
GO:0005515protein bindingIPI15231747 
GO:0005524ATP bindingIEA-
GO:0016787hydrolase activityIEA-
GO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesIEA-
GO:0008026ATP-dependent helicase activityIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CDC2L2CDC2L3 | CDK11-p110 | CDK11-p46 | CDK11-p58 | MGC131975 | PITSLRE | p58GTAcell division cycle 2-like 2 (PITSLRE proteins)-HPRD,BioGRID15231747 
EXOSC4FLJ20591 | RRP41 | RRP41A | Rrp41p | SKI6 | Ski6p | hRrp41p | p12Aexosome component 4-HPRD15231747 
WDR1AIP1 | NORI-1WD repeat domain 1-HPRD,BioGRID15231747 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_RNA_DEGRADATION 5937All SZGR genes in this pathway
WANG_CLIM2_TARGETS_UP 269146All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN 514319All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
NOUZOVA_TRETINOIN_AND_H4_ACETYLATION 14385All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_DN 14192All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_UP 245159All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN 254158All SZGR genes in this pathway
JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP 11573All SZGR genes in this pathway


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