Gene Page: TSC22D1

Summary
GeneID  8848
Symbol  TSC22D1
Synonyms  DKFZp686O19206|MGC17597|RP11-269C23.2|TGFB1I4|TSC22
Description  TSC22 domain family, member 1
See related  HGNC:16826|MIM:607715|Ensembl:ENSG00000102804|HPRD:07414|
Locus tag  -
Gene type  protein-coding
Map location  13q14
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0363 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SCN8A0.940.93
KCNB10.930.91
AP000751.30.920.92
MEF2D0.920.92
DLGAP20.910.84
TLN20.910.93
AAK10.910.94
SORL10.910.84
KCNMA10.900.80
LRRC8B0.900.86
Top 10 negatively co-expressed genes
DBI-0.46-0.62
RAB34-0.45-0.56
MYL12A-0.44-0.63
PECI-0.42-0.50
RAB13-0.42-0.53
RHOC-0.42-0.58
EFEMP2-0.42-0.44
C1orf61-0.42-0.61
C21orf57-0.41-0.41
C9orf46-0.41-0.38
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
GO:0006366transcription from RNA polymerase II promoterTAS9022669 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APLP1APLPamyloid beta (A4) precursor-like protein 1Two-hybridBioGRID16169070 
ASAH1AC | ASAH | FLJ21558 | FLJ22079 | PHP | PHP32N-acylsphingosine amidohydrolase (acid ceramidase) 1Two-hybridBioGRID16169070 
BAT3BAG-6 | BAG6 | D6S52E | G3HLA-B associated transcript 3Affinity Capture-MSBioGRID17353931 
CCDC90BMDS011 | MDS025 | MGC104239coiled-coil domain containing 90BTwo-hybridBioGRID16169070 
CDK2p33(CDK2)cyclin-dependent kinase 2Affinity Capture-MSBioGRID17353931 
COPB2beta'-COPcoatomer protein complex, subunit beta 2 (beta prime)Affinity Capture-MSBioGRID17353931 
CORO2BCLIPINC | KIAA0925coronin, actin binding protein, 2BTwo-hybridBioGRID16169070 
DYNC1H1DHC1 | DHC1a | DKFZp686P2245 | DNCH1 | DNCL | DNECL | DYHC | Dnchc1 | HL-3 | KIAA0325 | p22dynein, cytoplasmic 1, heavy chain 1Affinity Capture-MSBioGRID17353931 
EPPK1EPIPL | EPIPL1epiplakin 1Affinity Capture-MSBioGRID17353931 
GCN1L1GCN1 | GCN1L | KIAA0219GCN1 general control of amino-acid synthesis 1-like 1 (yeast)Affinity Capture-MSBioGRID17353931 
GSTK1GST13glutathione S-transferase kappa 1Affinity Capture-MSBioGRID17353931 
HEATR2FLJ20397 | FLJ25564 | FLJ31671 | FLJ39381HEAT repeat containing 2Affinity Capture-MSBioGRID17353931 
HNRNPMDKFZp547H118 | HNRNPM4 | HNRPM | HNRPM4 | HTGR1 | NAGR1heterogeneous nuclear ribonucleoprotein MAffinity Capture-MSBioGRID17353931 
IARSFLJ20736 | IARS1 | ILRS | PRO0785isoleucyl-tRNA synthetaseAffinity Capture-MSBioGRID17353931 
KIAA0090RP1-43E13.1KIAA0090Affinity Capture-MSBioGRID17353931 
MAP3K12DLK | MUK | ZPK | ZPKP1mitogen-activated protein kinase kinase kinase 12Two-hybridBioGRID16169070 
MTRFLJ33168 | FLJ43216 | FLJ45386 | MS5-methyltetrahydrofolate-homocysteine methyltransferaseAffinity Capture-MSBioGRID17353931 
NDUFA9MGC111043 | NDUFS2LNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDaAffinity Capture-MSBioGRID17353931 
NRBP1BCON3 | FLJ27109 | FLJ35541 | MADM | MUDPNP | NRBPnuclear receptor binding protein 1Affinity Capture-MSBioGRID17353931 
NUP93KIAA0095 | MGC21106nucleoporin 93kDaAffinity Capture-MSBioGRID17353931 
RGS11R20 | BL34 | IER1 | IR20regulator of G-protein signaling 1Two-hybridBioGRID16169070 
RPA3REPA3replication protein A3, 14kDaAffinity Capture-MSBioGRID17353931 
SETDB1ESET | KG1T | KIAA0067 | KMT1ESET domain, bifurcated 1Two-hybridBioGRID16169070 
SFXN1FLJ12876sideroflexin 1Affinity Capture-MSBioGRID17353931 
SLC25A22FLJ13044 | GC1solute carrier family 25 (mitochondrial carrier: glutamate), member 22Affinity Capture-MSBioGRID17353931 
SRPRBAPMCF1signal recognition particle receptor, B subunitAffinity Capture-MSBioGRID17353931 
TSC22D1DKFZp686O19206 | MGC17597 | RP11-269C23.2 | TGFB1I4 | TSC22TSC22 domain family, member 1Two-hybridBioGRID16169070 
TSC22D4THG-1 | THG1TSC22 domain family, member 4-HPRD10488076 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
HORIUCHI_WTAP_TARGETS_UP 306188All SZGR genes in this pathway
WANG_LMO4_TARGETS_UP 372227All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP 15791All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN 187115All SZGR genes in this pathway
DITTMER_PTHLH_TARGETS_UP 11268All SZGR genes in this pathway
ODONNELL_TFRC_TARGETS_UP 456228All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_6HR_DN 167100All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN 805505All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_UP 1915All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
CHEBOTAEV_GR_TARGETS_DN 12073All SZGR genes in this pathway
MARKEY_RB1_ACUTE_LOF_DN 228137All SZGR genes in this pathway
LANDIS_ERBB2_BREAST_TUMORS_65_DN 3722All SZGR genes in this pathway
LANDIS_ERBB2_BREAST_TUMORS_324_DN 14993All SZGR genes in this pathway
MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP 169127All SZGR genes in this pathway
RIZ_ERYTHROID_DIFFERENTIATION_12HR 4335All SZGR genes in this pathway
TSUNODA_CISPLATIN_RESISTANCE_DN 5138All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP 380213All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
BENPORATH_OCT4_TARGETS 290172All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
BENPORATH_NOS_TARGETS 179105All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
UEDA_PERIFERAL_CLOCK 169111All SZGR genes in this pathway
NELSON_RESPONSE_TO_ANDROGEN_UP 8661All SZGR genes in this pathway
JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN 6647All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN 8567All SZGR genes in this pathway
WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_DN 2415All SZGR genes in this pathway
FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP 8767All SZGR genes in this pathway
LENAOUR_DENDRITIC_CELL_MATURATION_DN 12890All SZGR genes in this pathway
WANG_TARGETS_OF_MLL_CBP_FUSION_DN 4531All SZGR genes in this pathway
AFFAR_YY1_TARGETS_UP 214133All SZGR genes in this pathway
TAKAO_RESPONSE_TO_UVB_RADIATION_UP 8655All SZGR genes in this pathway
KAAB_FAILED_HEART_ATRIUM_DN 14199All SZGR genes in this pathway
LEE_CALORIE_RESTRICTION_NEOCORTEX_UP 8366All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C6 3927All SZGR genes in this pathway
MCCLUNG_CREB1_TARGETS_DN 5739All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
TSENG_IRS1_TARGETS_DN 13588All SZGR genes in this pathway
BURTON_ADIPOGENESIS_1 3324All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G1 6741All SZGR genes in this pathway
TSENG_ADIPOGENIC_POTENTIAL_DN 4628All SZGR genes in this pathway
KAAB_FAILED_HEART_VENTRICLE_DN 4128All SZGR genes in this pathway
BILD_HRAS_ONCOGENIC_SIGNATURE 261166All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP 393244All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
MCCABE_BOUND_BY_HOXC6 469239All SZGR genes in this pathway
ZHENG_GLIOBLASTOMA_PLASTICITY_DN 5839All SZGR genes in this pathway
LABBE_TGFB1_TARGETS_UP 10264All SZGR genes in this pathway
CHEN_HOXA5_TARGETS_9HR_UP 223132All SZGR genes in this pathway
TSAI_RESPONSE_TO_RADIATION_THERAPY 3220All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_DN 5939All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN 315201All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_UP 418282All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP 408276All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_DN 209137All SZGR genes in this pathway
ZHANG_TLX_TARGETS_36HR_UP 221150All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
ZHANG_TLX_TARGETS_UP 10878All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN 9965All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION 422277All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_DN 210141All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G24 2819All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_M_G1 14895All SZGR genes in this pathway
RAGHAVACHARI_PLATELET_SPECIFIC_GENES 7046All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
KIM_GLIS2_TARGETS_UP 8461All SZGR genes in this pathway
BAKKER_FOXO3_TARGETS_DN 187109All SZGR genes in this pathway
KASLER_HDAC7_TARGETS_1_UP 194133All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN 448282All SZGR genes in this pathway
JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP 11573All SZGR genes in this pathway
ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF 516308All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101530536m8hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-124/506296302m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-1348187m8hsa-miR-134brainUGUGACUGGUUGACCAGAGGG
miR-200bc/4291471541A,m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-203.189951Ahsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-205623629m8hsa-miR-205UCCUUCAUUCCACCGGAGUCUG
miR-3816426481Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-542-3p502508m8hsa-miR-542-3pUGUGACAGAUUGAUAACUGAAA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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