Gene Page: NMI

Summary
GeneID  9111
Symbol  NMI
Synonyms  -
Description  N-myc (and STAT) interactor
See related  HGNC:7854|MIM:603525|Ensembl:ENSG00000123609|HPRD:04632|
Locus tag  -
Gene type  protein-coding
Map location  2q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02395 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003712transcription cofactor activityTAS10779520 
GO:0005515protein bindingIPI10597290 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006366transcription from RNA polymerase II promoterTAS9989503 
GO:0007259JAK-STAT cascadeTAS10597290 
GO:0006954inflammatory responseTAS9989503 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA18029348 
GO:0005737cytoplasmIDA10597290 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BRCA1BRCAI | BRCC1 | IRIS | PSCP | RNF53breast cancer 1, early onset-HPRD,BioGRID11916966 
BRCA1 interacts with Nmi.BIND11916966 
EMILIN1DKFZp586M121 | EMILIN | EMILIN-1 | gp115elastin microfibril interfacer 1Two-hybridBioGRID16189514 
GCSHGCE | NKHglycine cleavage system protein H (aminomethyl carrier)Two-hybridBioGRID16189514 
HDDC3MGC45386HD domain containing 3Two-hybridBioGRID16189514 
HGSHRS | ZFYVE8hepatocyte growth factor-regulated tyrosine kinase substrateTwo-hybridBioGRID16189514 
HHLA3-HERV-H LTR-associating 3Affinity Capture-Western
Two-hybrid		BioGRID16189514 
IFI35FLJ21753 | IFP35interferon-induced protein 35-HPRD,BioGRID10950963 
Nmi and IFP 35 associate into a high molecular mass complex (HMMC).BIND10950963 
LSM4YER112WLSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD,BioGRID15231747 
MYCbHLHe39 | c-Mycv-myc myelocytomatosis viral oncogene homolog (avian)-HPRD8668343 
Affinity Capture-Western
Reconstituted Complex		BioGRID11916966 
Myc interacts with NmiBIND11916966 
MYCNMODED | N-myc | NMYC | ODED | bHLHe37v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)-HPRD8668343 
NECAP2FLJ10420 | RP4-798A10.1NECAP endocytosis associated 2Two-hybridBioGRID16189514 
NMI-N-myc (and STAT) interactorNmi homodimerizes to form a complexBIND11916966 
PSMA1HC2 | MGC14542 | MGC14575 | MGC14751 | MGC1667 | MGC21459 | MGC22853 | MGC23915 | NU | PROS30proteasome (prosome, macropain) subunit, alpha type, 1Two-hybridBioGRID16189514 
SNAPC5SNAP19small nuclear RNA activating complex, polypeptide 5, 19kDaTwo-hybridBioGRID16189514 
STAT1DKFZp686B04100 | ISGF-3 | STAT91signal transducer and activator of transcription 1, 91kDa-HPRD,BioGRID9989503 
Nmi interacts with Stat1BIND9989503 
STAT3APRF | FLJ20882 | HIES | MGC16063signal transducer and activator of transcription 3 (acute-phase response factor)Nmi interacts with Stat3BIND9989503 
-HPRD,BioGRID9989503 
STAT4SLEB11signal transducer and activator of transcription 4Nmi interacts with Stat4. This interaction was modelled on a demonstrated interaction between Stat4 from an unspecified species and human Nmi.BIND9989503 
STAT5AMGF | STAT5signal transducer and activator of transcription 5ANmi interacts with Stat5aBIND9989503 
-HPRD,BioGRID9989503 
STAT5BSTAT5signal transducer and activator of transcription 5BNmi interacts with Stat5bBIND9989503 
-HPRD,BioGRID9989503 
STAT6D12S1644 | IL-4-STAT | STAT6B | STAT6Csignal transducer and activator of transcription 6, interleukin-4 inducedNmi interacts with Stat6BIND9989503 
TUBA3CTUBA2 | bA408E5.3tubulin, alpha 3cAffinity Capture-Western
Two-hybrid		BioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BIOCARTA_IL2RB_PATHWAY 3826All SZGR genes in this pathway
BIOCARTA_IL7_PATHWAY 1714All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN 463290All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
LIU_VMYB_TARGETS_UP 12778All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
PROVENZANI_METASTASIS_DN 13694All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP 11785All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_UP 584356All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
KORKOLA_YOLK_SAC_TUMOR 6233All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_DN 193112All SZGR genes in this pathway
PUJANA_BREAST_CANCER_LIT_INT_NETWORK 10173All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP 769437All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
BENPORATH_PROLIFERATION 14780All SZGR genes in this pathway
BENPORATH_ES_CORE_NINE_CORRELATED 10068All SZGR genes in this pathway
GEORGES_TARGETS_OF_MIR192_AND_MIR215 893528All SZGR genes in this pathway
CERVERA_SDHB_TARGETS_2 11476All SZGR genes in this pathway
DER_IFN_ALPHA_RESPONSE_UP 7448All SZGR genes in this pathway
BECKER_TAMOXIFEN_RESISTANCE_UP 5036All SZGR genes in this pathway
DER_IFN_BETA_RESPONSE_UP 10267All SZGR genes in this pathway
BROCKE_APOPTOSIS_REVERSED_BY_IL6 14498All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
SASAKI_ADULT_T_CELL_LEUKEMIA 176122All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
DER_IFN_GAMMA_RESPONSE_UP 7145All SZGR genes in this pathway
XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP 1713All SZGR genes in this pathway
ABBUD_LIF_SIGNALING_1_UP 4629All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP 314201All SZGR genes in this pathway
BROWNE_INTERFERON_RESPONSIVE_GENES 6844All SZGR genes in this pathway
GEISS_RESPONSE_TO_DSRNA_UP 3829All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN 271175All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_DN 220147All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_DN 228114All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
GRADE_COLON_AND_RECTAL_CANCER_UP 285167All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_DN 240153All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP 242159All SZGR genes in this pathway
CHICAS_RB1_TARGETS_GROWING 243155All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP 259159All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP 344215All SZGR genes in this pathway
YANG_BCL3_TARGETS_UP 364236All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_DN 244157All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway


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