Gene Page: PRPF4

Summary
GeneID  9128
Symbol  PRPF4
Synonyms  HPRP4|HPRP4P|PRP4|Prp4p
Description  PRP4 pre-mRNA processing factor 4 homolog (yeast)
See related  HGNC:17349|MIM:607795|Ensembl:ENSG00000136875|HPRD:08479|
Locus tag  -
Gene type  protein-coding
Map location  9q31-q33
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0357 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RIOK20.920.86
TAF70.910.87
CEBPZ0.910.88
SMNDC10.910.87
METAP20.910.89
N4BP2L20.910.90
SKIV2L20.900.85
PPP1CC0.900.84
QRSL10.900.85
C12orf110.890.85
Top 10 negatively co-expressed genes
MT-CO2-0.64-0.72
AF347015.31-0.63-0.73
AF347015.27-0.63-0.72
MT-CYB-0.63-0.72
AF347015.8-0.62-0.73
AF347015.15-0.62-0.73
AF347015.33-0.62-0.71
AF347015.2-0.60-0.71
IFI27-0.59-0.72
PTH1R-0.58-0.69
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0031202RNA splicing factor activity, transesterification mechanismNAS9328476 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000398nuclear mRNA splicing, via spliceosomeEXP12226669 
GO:0008380RNA splicingNAS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusTAS9328476 
GO:0005681spliceosomeNAS9328476 
GO:0016607nuclear speckIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ATP5J2ATP5JLATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2Two-hybridBioGRID16169070 
CLK1CLK | CLK/STY | STYCDC-like kinase 1-HPRD,BioGRID11418604 
PPIHCYP-20 | CYPH | MGC5016 | SnuCyp-20 | USA-CYPpeptidylprolyl isomerase H (cyclophilin H)-HPRD12875835 |12907720 
SART3DSAP1 | KIAA0156 | MGC138188 | P100 | RP11-13G14 | TIP110 | p110 | p110(nrb)squamous cell carcinoma antigen recognized by T cells 3FRETBioGRID15452143 
SFRS1ASF | MGC5228 | SF2 | SF2p33 | SRp30asplicing factor, arginine/serine-rich 1-HPRD,BioGRID11418604 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SPLICEOSOME 12872All SZGR genes in this pathway
REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 14077All SZGR genes in this pathway
REACTOME_MRNA_PROCESSING 16186All SZGR genes in this pathway
REACTOME_MRNA_SPLICING 11158All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_UP 430232All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN 14184All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_WITH_LOH_IN_CHR9Q 11671All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP 309199All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
PUJANA_XPRSS_INT_NETWORK 168103All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_BRCA2_PCC_NETWORK 423265All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
PUJANA_BRCA_CENTERED_NETWORK 11772All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
YAGI_AML_SURVIVAL 12987All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_16HR_UP 225139All SZGR genes in this pathway
BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_DN 6045All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP 393244All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN 409268All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP 439257All SZGR genes in this pathway
FOURNIER_ACINAR_DEVELOPMENT_LATE_2 277172All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN 448282All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.