Gene Page: DNER

Summary
GeneID  92737
Symbol  DNER
Synonyms  UNQ26|bet
Description  delta/notch-like EGF repeat containing
See related  HGNC:24456|MIM:607299|Ensembl:ENSG00000187957|HPRD:09531|
Locus tag  -
Gene type  protein-coding
Map location  2q36.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 7 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0030276clathrin bindingTASSynap (GO term level: 4)11950833 
GO:0004888transmembrane receptor activityTAS11950833 
GO:0005112Notch bindingIEA-
GO:0005509calcium ion bindingNAS11950833 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007417central nervous system developmentIEPBrain (GO term level: 6)11950833 
GO:0007416synaptogenesisNASSynap (GO term level: 6)11950833 
GO:0001764neuron migrationNASneuron (GO term level: 8)11950833 
GO:0010001glial cell differentiationIEAGlial (GO term level: 8)-
GO:0007220Notch receptor processingIEA-
GO:0006897endocytosisNAS11950833 
GO:0048741skeletal muscle fiber developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0043025cell somaIEAaxon, dendrite (GO term level: 4)-
GO:0030425dendriteIDAneuron, axon, dendrite (GO term level: 6)11950833 
GO:0005769early endosomeIDA11950833 
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneIDA11950833 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AP1G1ADTG | CLAPG1 | MGC18255adaptor-related protein complex 1, gamma 1 subunit-HPRD11950833 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_NOTCH_PATHWAY 5949All SZGR genes in this pathway
REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS 2718All SZGR genes in this pathway
REACTOME_SIGNALING_BY_NOTCH1 7046All SZGR genes in this pathway
REACTOME_SIGNALING_BY_NOTCH 10364All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN 349157All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN 17582All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_DN 367220All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
TOMIDA_METASTASIS_UP 2613All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_DN 9751All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP 11679All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP 3532All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM 302191All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
KONDO_EZH2_TARGETS 245148All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN 229135All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
KATSANOU_ELAVL1_TARGETS_UP 169105All SZGR genes in this pathway
KOHOUTEK_CCNT1_TARGETS 5026All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN 308187All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-148/152534540m8hsa-miR-148aUCAGUGCACUACAGAACUUUGU
hsa-miR-152brainUCAGUGCAUGACAGAACUUGGG
hsa-miR-148bUCAGUGCAUCACAGAACUUUGU
miR-320138144m8hsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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