Gene Page: GDA

Summary
GeneID  9615
Symbol  GDA
Synonyms  CYPIN|GUANASE|KIAA1258|MGC9982|NEDASIN
Description  guanine deaminase
See related  HGNC:4212|MIM:139260|Ensembl:ENSG00000119125|HPRD:08849|
Locus tag  RP11-63P12.1
Gene type  protein-coding
Map location  9q21.13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CEP680.910.94
UBN10.900.94
KSR10.900.92
SRGAP30.900.94
POM1210.900.92
POM121C0.890.93
LARP4B0.890.93
BICD20.890.93
TBC1D240.890.93
TGFBRAP10.890.92
Top 10 negatively co-expressed genes
AF347015.31-0.65-0.71
MT-CO2-0.65-0.72
FXYD1-0.64-0.68
AF347015.21-0.63-0.77
HIGD1B-0.63-0.70
C1orf54-0.62-0.80
AC021016.1-0.62-0.68
S100B-0.62-0.67
AF347015.33-0.61-0.65
MT-CYB-0.61-0.66
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0016787hydrolase activityIEA-
GO:0008892guanine deaminase activityEXP10075721 
GO:0008892guanine deaminase activityIEA-
GO:0008892guanine deaminase activityTAS10075721 
GO:0008270zinc ion bindingTAS10075721 
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)10542258 
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic processTAS10075721 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP10075721 
GO:0005622intracellularTAS10542258 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DLG1DKFZp761P0818 | DKFZp781B0426 | DLGH1 | SAP97 | dJ1061C18.1.1 | hdlgdiscs, large homolog 1 (Drosophila)-HPRD10595517 
DLG3KIAA1232 | MRX | MRX90 | NE-Dlg | NEDLG | SAP102discs, large homolog 3 (neuroendocrine-dlg, Drosophila)-HPRD,BioGRID10542258 |10595517 
DLG4FLJ97752 | FLJ98574 | PSD95 | SAP90discs, large homolog 4 (Drosophila)-HPRD10595517 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PURINE_METABOLISM 15996All SZGR genes in this pathway
REACTOME_METABOLISM_OF_NUCLEOTIDES 7245All SZGR genes in this pathway
REACTOME_PURINE_CATABOLISM 106All SZGR genes in this pathway
REACTOME_PURINE_METABOLISM 3324All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN 17582All SZGR genes in this pathway
RODRIGUES_NTN1_TARGETS_DN 158102All SZGR genes in this pathway
WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP 13784All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP 191128All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_E 8944All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_UP 3124All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR 544307All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN 409268All SZGR genes in this pathway
COATES_MACROPHAGE_M1_VS_M2_UP 8152All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP 180114All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_DN 252155All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN 170105All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
ZEMBUTSU_SENSITIVITY_TO_NIMUSTINE 1713All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_UP 2014All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP 271165All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway
ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION 12881All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-129-5p80861Ahsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-130/301569575m8hsa-miR-130abrainCAGUGCAAUGUUAAAAGGGCAU
hsa-miR-301CAGUGCAAUAGUAUUGUCAAAGC
hsa-miR-130bbrainCAGUGCAAUGAUGAAAGGGCAU
hsa-miR-454-3pUAGUGCAAUAUUGCUUAUAGGGUUU
miR-19568574m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-485-3p38003806m8hsa-miR-485-3pGUCAUACACGGCUCUCCUCUCU
miR-505214621531A,m8hsa-miR-505GUCAACACUUGCUGGUUUCCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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