Gene Page: SEPT7

Summary
GeneID  989
Symbol  SEPT7
Synonyms  CDC10|CDC3|Nbla02942|SEPT7A
Description  septin 7
See related  HGNC:1717|MIM:603151|HPRD:04398|
Locus tag  -
Gene type  protein-coding
Map location  7p14.3-p14.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
WDR620.830.73
RAD54L0.810.57
E2F10.810.78
SPAG50.800.63
GSX20.800.23
NCAPD20.790.55
NOTCH10.790.56
SALL10.790.69
CDT10.790.46
MCM30.790.68
Top 10 negatively co-expressed genes
AF347015.21-0.35-0.30
AF347015.31-0.31-0.25
IL32-0.30-0.34
AF347015.8-0.30-0.23
AF347015.18-0.30-0.25
MT-CO2-0.30-0.23
SYCP3-0.29-0.33
C1orf54-0.28-0.26
MT-ATP8-0.28-0.23
MT-CYB-0.27-0.20
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005515protein bindingIEA-
GO:0005515protein bindingIPI15485874 
GO:0005525GTP bindingIEA-
GO:0005525GTP bindingTAS8037772 
GO:0005198structural molecule activityTAS8037772 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000910cytokinesisTAS8037772 
GO:0007049cell cycleIEA-
GO:0051291protein heterooligomerizationIDA15485874 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0019717synaptosomeIEASynap, Brain (GO term level: 7)-
GO:0001725stress fiberIDA15485874 
GO:0005634nucleusIDA15485874 
GO:0031105septin complexIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ANLNDKFZp779A055 | Scraps | scraanillin, actin binding protein-HPRD,BioGRID10931866 
CDC42EP2BORG1 | CEP2CDC42 effector protein (Rho GTPase binding) 2-HPRD,BioGRID11584266 
CDC42EP3BORG2 | CEP3 | FLJ46903 | UB1CDC42 effector protein (Rho GTPase binding) 3Reconstituted ComplexBioGRID11584266 
CDC42EP5Borg3 | CEP5 | MGC21945 | MGC71153CDC42 effector protein (Rho GTPase binding) 5-HPRD11584266 
S100A418A2 | 42A | CAPL | FSP1 | MTS1 | P9KA | PEL98S100 calcium binding protein A4-HPRD14531065 
SEPT2DIFF6 | KIAA0158 | NEDD5 | Pnutl3 | hNedd5septin 2Affinity Capture-MS
Affinity Capture-Western		BioGRID12388755 |17353931 
SEPT9AF17q25 | FLJ75490 | KIAA0991 | MSF | MSF1 | NAPB | PNUTL4 | SINT1 | SeptD1septin 9-HPRD,BioGRID12388755 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
WATANABE_COLON_CANCER_MSI_VS_MSS_DN 8142All SZGR genes in this pathway
CHANDRAN_METASTASIS_TOP50_UP 3827All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_DN 244147All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_DN 536332All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP 544308All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
CALVET_IRINOTECAN_SENSITIVE_VS_RESISTANT_DN 55All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN 10364All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP 157105All SZGR genes in this pathway
STONER_ESOPHAGEAL_CARCINOGENESIS_UP 3925All SZGR genes in this pathway
IGLESIAS_E2F_TARGETS_UP 151103All SZGR genes in this pathway
MURAKAMI_UV_RESPONSE_6HR_UP 3731All SZGR genes in this pathway
MA_PITUITARY_FETAL_VS_ADULT_UP 2921All SZGR genes in this pathway
JIANG_AGING_CEREBRAL_CORTEX_DN 5443All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
MCCABE_BOUND_BY_HOXC6 469239All SZGR genes in this pathway
MCCABE_HOXC6_TARGETS_UP 108All SZGR genes in this pathway
MCCABE_HOXC6_TARGETS_CANCER_UP 3123All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_UP 374247All SZGR genes in this pathway
LEE_LIVER_CANCER_SURVIVAL_DN 175103All SZGR genes in this pathway
WENDT_COHESIN_TARGETS_UP 3319All SZGR genes in this pathway
MILI_PSEUDOPODIA 4327All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_UP 7445All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_UP 518299All SZGR genes in this pathway
CHANDRAN_METASTASIS_UP 221135All SZGR genes in this pathway
MURAKAMI_UV_RESPONSE_1HR_UP 1710All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_A 182108All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1276773m8hsa-miR-127brainUCGGAUCCGUCUGAGCUUGGCU
miR-141/200a5662m8hsa-miR-141UAACACUGUCUGGUAAAGAUGG
hsa-miR-200aUAACACUGUCUGGUAACGAUGU
miR-1496306361Ahsa-miR-149brainUCUGGCUCCGUGUCUUCACUCC
miR-1823238m8hsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-1833693751Ahsa-miR-183UAUGGCACUGGUAGAAUUCACUG
miR-1865905971A,m8hsa-miR-186CAAAGAAUUCUCCUUUUGGGCUU
miR-198389m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-2161551611Ahsa-miR-216UAAUCUCAGCUGGCAACUGUG
miR-2192882941Ahsa-miR-219brainUGAUUGUCCAAACGCAAUUCU
miR-24*8198251Ahsa-miR-189GUGCCUACUGAGCUGAUAUCAGU
miR-30-5p3123191A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-3258798851Ahsa-miR-325CCUAGUAGGUGUCCAGUAAGUGU
miR-332622681Ahsa-miR-33GUGCAUUGUAGUUGCAUUG
hsa-miR-33bGUGCAUUGCUGUUGCAUUGCA
miR-3359019071Ahsa-miR-335brainUCAAGAGCAAUAACGAAAAAUGU
miR-376397403m8hsa-miR-376aAUCAUAGAGGAAAAUCCACGU
hsa-miR-376bAUCAUAGAGGAAAAUCCAUGUU
miR-452382388m8hsa-miR-452UGUUUGCAGAGGAAACUGAGAC
miR-493-5p2852911Ahsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-495575581m8hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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