| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3014 |
Name | H2AFX |
Synonym | H2A.X|H2A/X|H2AX;H2A histone family, member X;H2AFX;H2A histone family, member X |
Definition | H2AX histone|histone H2A.x|histone H2AX |
Position | 11q23.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 8193 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | DNA Repair;Reactome;REACT:216 |
Pathway | MRN complex relocalizes to nuclear foci;PID Reactome;500045 |
Pathway | Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks;PID Reactome;500950 |
Pathway | Chromosome Maintenance;Reactome;REACT:22172 |
Pathway | Recruitment of repair and signaling proteins to double-strand breaks;PID Reactome;500044 |
Pathway | Systemic lupus erythematosus;KEGG PATHWAY;hsa05322 |
Pathway | ATM mediated phosphorylation of repair proteins;PID Reactome;500043 |
|
External Links |
|
Links to Entrez Gene | 3014 |
Links to all GeneRIF Items | 3014 |
Links to iHOP | 3014 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3014 : length: 432 atgtcgggccgcggcaagactggcggcaaggcccgcgccaaggccaagtcgcgctcgtcg cgcgccggcctccagttcccagtgggccgtgtacaccggctgctgcggaagggccactac gccgagcgcgttggcgccggcgcgccagtgtacctggcggcagtgctggagtacctcacc gctgagatcctggagctggcgggcaatgcggcccgcgacaacaagaagacgcgaatcatc ccccgccacctgcagctggccatccgcaacgacgaggagctcaacaagctgctgggcggc gtgacgatcgcccagggaggcgtcctgcccaacatccaggccgtgctgctgcccaagaag accagcgccaccgtggggccgaaggcgccctcgggcggcaagaaggccacccaggcctcc caggagtactaa |
Protein Sequence |
>3014 : length: 143 MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLT AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKK TSATVGPKAPSGGKKATQASQEY |