Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3014

Name

H2AFX

Synonymous

H2A.X|H2A/X|H2AX;H2A histone family, member X;H2AFX;H2A histone family, member X

Definition

H2AX histone|histone H2A.x|histone H2AX

Position

11q23.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 ATMNCI_NATURE;

in same component

 ATMREACTOME;

in same component

 ATRREACTOME;

in same component

 BRCA1NCI_NATURE;

in same component

 BRCA1REACTOME;

in same component

 BRCA2REACTOME;

in same component

 CDK4REACTOME;

in same component

 DMC1REACTOME;

in same component

 FAM175ANCI_NATURE;

in same component

 FANCD2NCI_NATURE;

in same component

 FANCINCI_NATURE;

in same component

 HIST3H3REACTOME;

in same component

 MDC1NCI_NATURE;

in same component

 MDC1REACTOME;

in same component

 MRE11ANCI_NATURE;

in same component

 MRE11AREACTOME;

in same component

 NBNNCI_NATURE;

in same component

 NBNREACTOME;

in same component

 RAD21REACTOME;

in same component

 RAD50NCI_NATURE;

in same component

 RAD50REACTOME;

in same component

 RAD51REACTOME;

in same component

 REC8REACTOME;

in same component

 RNF8NCI_NATURE;

in same component

 RPA1REACTOME;

in same component

 RPA2REACTOME;

in same component

 RPA3REACTOME;

in same component

 SMC1AREACTOME;

in same component

 SMC1BREACTOME;

in same component

 SMC3REACTOME;

in same component

 STAG1REACTOME;

in same component

 STAG2REACTOME;

in same component

 STAG3REACTOME;

in same component

 SYCP2REACTOME;

in same component

 SYCP3REACTOME;

in same component

 TP53BP1NCI_NATURE;

in same component

 TP53BP1REACTOME;

in same component

 UIMC1NCI_NATURE;

interacts with

 ABHD10BIOGRID;

interacts with

 ACTA2MINT;

interacts with

 ACTBMINT;

interacts with

 ACTG1MINT;

interacts with

 ACTN2MINT;

interacts with

 ACTN3MINT;

interacts with

 ACTR5INTACT;

interacts with

 AIFM1BIOGRID;

interacts with

 Aifm1MINT;

interacts with

 ALDOABIOGRID;

interacts with

 ALG9HPRD;

interacts with

 ANKRD18AMINT;

interacts with

 ANXA2BIOGRID;

interacts with

 ANXA4BIOGRID;

interacts with

 ANXA5BIOGRID;

interacts with

 ANXA6BIOGRID;

interacts with

 APOA1BPBIOGRID;

interacts with

 ARHGEF4MINT;

interacts with

 ATMBIOGRID;

interacts with

 ATMHPRD;

interacts with

 ATMMINT;

interacts with

 ATP5A1MINT;

interacts with

 ATRBIOGRID;

interacts with

 BANK1MINT;

interacts with

 BARD1BIOGRID;

interacts with

 BIRC5BIOGRID;

interacts with

 BLMBIOGRID;

interacts with

 BLMHPRD;

interacts with

 BRCA1BIOGRID;

interacts with

 BRCA2BIOGRID;

interacts with

 BRD1BIOGRID;

interacts with

 BTF3BIOGRID;

interacts with

 CACNA1SMINT;

interacts with

 CALM1BIOGRID;

interacts with

 CALM1MINT;

interacts with

 CALRBIOGRID;

interacts with

 CBLMINT;

interacts with

 CBX1HPRD;

interacts with

 CBX5HPRD;

interacts with

 CCDC19BIOGRID;

interacts with

 CCT5BIOGRID;

interacts with

 CEP250MINT;

interacts with

 CFL1BIOGRID;

interacts with

 CHD1LBIOGRID;

interacts with

 CLUBIOGRID;

interacts with

 CMBLBIOGRID;

interacts with

 CPS1BIOGRID;

interacts with

 CTSDBIOGRID;

interacts with

 CUL1MINT;

interacts with

 CUL2MINT;

interacts with

 CUL3MINT;

interacts with

 CUL4AMINT;

interacts with

 CUL4BMINT;

interacts with

 CUL5MINT;

interacts with

 DDB1MINT;

interacts with

 DDX21HPRD;

interacts with

 DEKHPRD;

interacts with

 DESMINT;

interacts with

 DHX30BIOGRID;

interacts with

 DHX9BIOGRID;

interacts with

 DMAP1BIOGRID;

interacts with

 EEF1A1BIOGRID;

interacts with

 EEF1A1MINT;

interacts with

 EEF1A2MINT;

interacts with

 EEF1B2BIOGRID;

interacts with

 EEF2MINT;

interacts with

 EIF2AMINT;

interacts with

 EIF2S2BIOGRID;

interacts with

 EIF3LBIOGRID;

interacts with

 EIF4A1BIOGRID;

interacts with

 ELAVL1BIOGRID;

interacts with

 EMG1MINT;

interacts with

 ENO1BIOGRID;

interacts with

 ERCC4MINT;

interacts with

 ERO1LBIOGRID;

interacts with

 ERP29BIOGRID;

interacts with

 EYA1BIOGRID;

interacts with

 EYA3BIOGRID;

interacts with

 FAM82BBIOGRID;

interacts with

 FANCD2BIOGRID;

interacts with

 FANCD2MINT;

interacts with

 FKBP10BIOGRID;

interacts with

 FOXO3BIOGRID;

interacts with

 GANABBIOGRID;

interacts with

 GCN1L1MINT;

interacts with

 GLB1BIOGRID;

interacts with

 H1F0MINT;

interacts with

 H2AFYHPRD;

interacts with

 HARSMINT;

interacts with

 HAT1BIOGRID;

interacts with

 HAT1MINT;

interacts with

 HEXABIOGRID;

interacts with

 HIBCHBIOGRID;

interacts with

 HIST1H1AHPRD;

interacts with

 HIST1H1CMINT;

interacts with

 HIST1H1DMINT;

interacts with

 HIST1H1TMINT;

interacts with

 HIST1H2AGMINT;

interacts with

 HIST1H2BCBIOGRID;

interacts with

 HIST1H2BCHPRD;

interacts with

 HIST1H2BDMINT;

interacts with

 HIST1H2BMBIOGRID;

interacts with

 HIST2H2ACBIOGRID;

interacts with

 HIST2H2BEBIOGRID;

interacts with

 HIST2H2BEMINT;

interacts with

 HIST3H3MINT;

interacts with

 HNRNPA1BIOGRID;

interacts with

 HNRNPA2B1BIOGRID;

interacts with

 HNRNPA2B1MINT;

interacts with

 HNRNPABBIOGRID;

interacts with

 HNRNPCBIOGRID;

interacts with

 HNRNPCMINT;

interacts with

 HNRNPDBIOGRID;

interacts with

 HNRNPH3BIOGRID;

interacts with

 HNRNPRBIOGRID;

interacts with

 HNRPDLBIOGRID;

interacts with

 HP1BP3HPRD;

interacts with

 HSD17B10BIOGRID;

interacts with

 HSP90AA1BIOGRID;

interacts with

 HSP90B1BIOGRID;

interacts with

 HSPA1LBIOGRID;

interacts with

 HSPA5BIOGRID;

interacts with

 HSPA6HPRD;

interacts with

 HSPA9BIOGRID;

interacts with

 HYOU1BIOGRID;

interacts with

 ILF2BIOGRID;

interacts with

 INO80INTACT;

interacts with

 KARSMINT;

interacts with

 KAT2ABIOGRID;

interacts with

 KAT2AMINT;

interacts with

 KAT2BBIOGRID;

interacts with

 KAT2BMINT;

interacts with

 KAT5BIOGRID;

interacts with

 KAT5MINT;

interacts with

 KRT17MINT;

interacts with

 KRT18MINT;

interacts with

 KRT8MINT;

interacts with

 LDHBBIOGRID;

interacts with

 LEPRE1BIOGRID;

interacts with

 LGALS3BPBIOGRID;

interacts with

 LMNABIOGRID;

interacts with

 LMNAMINT;

interacts with

 MAPK8BIOGRID;

interacts with

 MATR3BIOGRID;

interacts with

 MCM4MINT;

interacts with

 MCM5MINT;

interacts with

 MDC1BIOGRID;

interacts with

 MDC1HPRD;

interacts with

 MDC1MINT;

interacts with

 MRE11ABIOGRID;

interacts with

 MRE11AHPRD;

interacts with

 MRE11AMINT;

interacts with

 MSI2BIOGRID;

interacts with

 MSNBIOGRID;

interacts with

 MYH11MINT;

interacts with

 MYH13MINT;

interacts with

 MYH2MINT;

interacts with

 MYH3MINT;

interacts with

 MYH7MINT;

interacts with

 MYH9MINT;

interacts with

 MYL12AMINT;

interacts with

 MYL3MINT;

interacts with

 MYLK2MINT;

interacts with

 MYST1BIOGRID;

interacts with

 MYST1MINT;

interacts with

 NACABIOGRID;

interacts with

 NAE1MINT;

interacts with

 NBNBIOGRID;

interacts with

 NBNHPRD;

interacts with

 NBNMINT;

interacts with

 NEDD8MINT;

interacts with

 NHEJ1MINT;

interacts with

 NLRP2MINT;

interacts with

 NONOBIOGRID;

interacts with

 P4HA2BIOGRID;

interacts with

 P4HBBIOGRID;

interacts with

 PABPC1BIOGRID;

interacts with

 PAPPABIOGRID;

interacts with

 PARP1BIOGRID;

interacts with

 PARP1HPRD;

interacts with

 PBKBIOGRID;

interacts with

 PCBP2BIOGRID;

interacts with

 PCNAMINT;

interacts with

 PDCD6BIOGRID;

interacts with

 PDIA4BIOGRID;

interacts with

 PDIA6BIOGRID;

interacts with

 PEF1BIOGRID;

interacts with

 PGK1BIOGRID;

interacts with

 PIAS1MINT;

interacts with

 PIAS2MINT;

interacts with

 PKM2BIOGRID;

interacts with

 PLOD1BIOGRID;

interacts with

 POFUT1BIOGRID;

interacts with

 POLR2ABIOGRID;

interacts with

 PPIABIOGRID;

interacts with

 PPM1DBIOGRID;

interacts with

 PPM1GBIOGRID;

interacts with

 PPP1CAHPRD;

interacts with

 PPP2R4BIOGRID;

interacts with

 PRDX3BIOGRID;

interacts with

 PRDX4BIOGRID;

interacts with

 PRDX6BIOGRID;

interacts with

 PRKCSHBIOGRID;

interacts with

 PRKDCBIOGRID;

interacts with

 PRMT5HPRD;

interacts with

 PRPF3MINT;

interacts with

 PSMB3BIOGRID;

interacts with

 PSMB4BIOGRID;

interacts with

 PTCD3BIOGRID;

interacts with

 PTGES2BIOGRID;

interacts with

 RAB11BBIOGRID;

interacts with

 RAD17BIOGRID;

interacts with

 RAD50BIOGRID;

interacts with

 RAD50MINT;

interacts with

 RAD51BIOGRID;

interacts with

 RALYMINT;

interacts with

 RANHPRD;

interacts with

 RCC1HPRD;

interacts with

 RNF168BIOGRID;

interacts with

 RPL12MINT;

interacts with

 RPL13MINT;

interacts with

 RPL18MINT;

interacts with

 RPL21MINT;

interacts with

 RPL29MINT;

interacts with

 RPL35AMINT;

interacts with

 RPL5MINT;

interacts with

 RPL6MINT;

interacts with

 RPL7MINT;

interacts with

 RPL9MINT;

interacts with

 RPLP2BIOGRID;

interacts with

 RPN2BIOGRID;

interacts with

 RPS10BIOGRID;

interacts with

 RPS2MINT;

interacts with

 RPS3MINT;

interacts with

 RPS6KA3BIOGRID;

interacts with

 RUVBL1BIOGRID;

interacts with

 S100A4BIOGRID;

interacts with

 SF3B3MINT;

interacts with

 SLC25A6BIOGRID;

interacts with

 SMARCA2BIOGRID;

interacts with

 SMARCA2MINT;

interacts with

 SMARCA4BIOGRID;

interacts with

 SMARCA4MINT;

interacts with

 SOD2BIOGRID;

interacts with

 SSBBIOGRID;

interacts with

 SSBP1BIOGRID;

interacts with

 SSRP1BIOGRID;

interacts with

 SSRP1MINT;

interacts with

 STK4BIOGRID;

interacts with

 SUMF2BIOGRID;

interacts with

 SUMO3MINT;

interacts with

 SUPT16HBIOGRID;

interacts with

 SUPT5HHPRD;

interacts with

 SYNCRIPBIOGRID;

interacts with

 TARSMINT;

interacts with

 TDP1MINT;

interacts with

 TGIF2LYMINT;

interacts with

 THOC4BIOGRID;

interacts with

 TKTBIOGRID;

interacts with

 TMX1BIOGRID;

interacts with

 TOP1HPRD;

interacts with

 TOR1ABIOGRID;

interacts with

 TOR1BBIOGRID;

interacts with

 TP53BP1BIOGRID;

interacts with

 TP53BP1HPRD;

interacts with

 TP53BP1MINT;

interacts with

 TP53BIOGRID;

interacts with

 TP53I3BIOGRID;

interacts with

 TPM1MINT;

interacts with

 TRAP1BIOGRID;

interacts with

 TSC2MINT;

interacts with

 TSSK6BIOGRID;

interacts with

 TTNMINT;

interacts with

 TUBB2AMINT;

interacts with

 UBE2MMINT;

interacts with

 USP42MINT;

interacts with

 VASPMINT;

interacts with

 VAT1BIOGRID;

interacts with

 VIMMINT;

interacts with

 VPS35BIOGRID;

interacts with

 WDR77HPRD;

interacts with

 WRNBIOGRID;

interacts with

 WRNHPRD;

interacts with

 WRNMINT;

interacts with

 XPCBIOGRID;

interacts with

 XRCC1MINT;

interacts with

 XRCC5BIOGRID;

interacts with

 XRCC5HPRD;

interacts with

 XRCC6BIOGRID;

interacts with

 XRCC6HPRD;

interacts with

 YWHABBIOGRID;

interacts with

 YWHAEBIOGRID;

interacts with

 YWHAEMINT;

interacts with

 YWHAGMINT;

interacts with

 YWHAHMINT;

interacts with

 YWHAQMINT;

interacts with

 YWHAZBIOGRID;

interacts with

 YWHAZMINT;

Metabolic Interaction   [Top]

There is no record for H2AFX

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 ATMNCI_NATURE;

reacts with

 ATMREACTOME;

reacts with

 ATRREACTOME;

reacts with

 BLMREACTOME;

reacts with

 BRCA1NCI_NATURE;

reacts with

 BRCA1REACTOME;

reacts with

 BRCA2REACTOME;

reacts with

 CDK4REACTOME;

reacts with

 CTBP1NCI_NATURE;

reacts with

 DMC1REACTOME;

reacts with

 FAM175ANCI_NATURE;

reacts with

 FANCD2NCI_NATURE;

reacts with

 FANCINCI_NATURE;

reacts with

 H2AFXNCI_NATURE;

reacts with

 H2AFXREACTOME;

reacts with

 HIST3H3REACTOME;

reacts with

 MDC1NCI_NATURE;

reacts with

 MDC1REACTOME;

reacts with

 MRE11ANCI_NATURE;

reacts with

 MRE11AREACTOME;

reacts with

 MSH4REACTOME;

reacts with

 MSH5REACTOME;

reacts with

 NBNNCI_NATURE;

reacts with

 NBNREACTOME;

reacts with

 RAD21REACTOME;

reacts with

 RAD50NCI_NATURE;

reacts with

 RAD50REACTOME;

reacts with

 RAD51REACTOME;

reacts with

 RBBP8NCI_NATURE;

reacts with

 REC8REACTOME;

reacts with

 RNF8NCI_NATURE;

reacts with

 RPA1REACTOME;

reacts with

 RPA2REACTOME;

reacts with

 RPA3REACTOME;

reacts with

 SMC1AREACTOME;

reacts with

 SMC1BREACTOME;

reacts with

 SMC3REACTOME;

reacts with

 STAG1REACTOME;

reacts with

 STAG2REACTOME;

reacts with

 STAG3REACTOME;

reacts with

 SYCP2REACTOME;

reacts with

 SYCP3REACTOME;

reacts with

 TOP3AREACTOME;

reacts with

 TP53BP1NCI_NATURE;

reacts with

 TP53BP1REACTOME;

reacts with

 UIMC1NCI_NATURE;

state change

 ATMNCI_NATURE;

state change

 ATMREACTOME;

state change

 ATRREACTOME;

state change

 BRCA1NCI_NATURE;

state change

 BRCA1REACTOME;

state change

 BRCA2REACTOME;

state change

 CDK4REACTOME;

state change

 DMC1REACTOME;

state change

 H2AFXREACTOME;

state change

 HIST3H3REACTOME;

state change

 MDC1REACTOME;

state change

 MND1REACTOME;

state change

 MRE11ANCI_NATURE;

state change

 NBNNCI_NATURE;

state change

 PSMC3IPREACTOME;

state change

 RAD21REACTOME;

state change

 RAD50NCI_NATURE;

state change

 RAD51CREACTOME;

state change

 RAD51REACTOME;

state change

 REC8REACTOME;

state change

 RPA1REACTOME;

state change

 RPA2REACTOME;

state change

 RPA3REACTOME;

state change

 SMC1AREACTOME;

state change

 SMC1BREACTOME;

state change

 SMC3REACTOME;

state change

 STAG1REACTOME;

state change

 STAG2REACTOME;

state change

 STAG3REACTOME;

state change

 SYCP2REACTOME;

state change

 SYCP3REACTOME;

state change

 TEX15REACTOME;

state change

 UBE2NNCI_NATURE;

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