| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 835 |
Name | CASP2 |
Synonym | CASP-2|ICH1|NEDD-2|NEDD2|PPP1R57;caspase 2, apoptosis-related cysteine peptidase;CASP2;caspase 2, apoptosis-related cysteine peptidase |
Definition | caspase-2|neural precursor cell expressed developmentally down-regulated protein 2|protease ICH-1|protein phosphatase 1, regulatory subunit 57 |
Position | 7q34-q35 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 4268 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Caspase cascade in apoptosis;PID Curated;200148 |
Pathway | hiv-1 nef: negative effector of fas and tnf;PID BioCarta;100144 |
Pathway | HIV-1 Nef: Negative effector of Fas and TNF-alpha;PID Curated;200133 |
Pathway | tnf/stress related signaling;PID BioCarta;100026 |
Pathway | caspase cascade in apoptosis;PID BioCarta;100218 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | tnfr1 signaling pathway;PID BioCarta;100015 |
Disease | Breast cancer;FunDO |
Disease | Stomach cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 835 |
Links to all GeneRIF Items | 835 |
Links to iHOP | 835 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>835 : length: 1359 atggcggcgccgagcgcggggtcttggtccaccttccagcacaaggagctgatggccgct gacaggggacgcaggatattgggagtgtgtggcatgcatcctcatcatcaggaaactcta aaaaagaaccgagtggtgctagccaaacagctgttgttgagcgaattgttagaacatctt ctggagaaggacatcatcaccttggaaatgagggagctcatccaggccaaagtgggcagt ttcagccagaatgtggaactcctcaacttgctgcctaagaggggtccccaagcttttgat gccttctgtgaagcactgagggagaccaagcaaggccacctggaggatatgttgctcacc accctttctgggcttcagcatgtactcccaccgttgagctgtgactacgacttgagtctc ccttttccggtgtgtgagtcctgtcccctttacaagaagctccgcctgtcgacagatact gtggaacactccctagacaataaagatggtcctgtctgccttcaggtgaagccttgcact cctgaattttatcaaacacacttccagctggcatataggttgcagtctcggcctcgtggc ctagcactggtgttgagcaatgtgcacttcactggagagaaagaactggaatttcgctct ggaggggatgtggaccacagtactctagtcaccctcttcaagcttttgggctatgacgtc catgttctatgtgaccagactgcacaggaaatgcaagagaaactgcagaattttgcacag ttacctgcacaccgagtcacggactcctgcatcgtggcactcctctcgcatggtgtggag ggcgccatctatggtgtggatgggaaactgctccagctccaagaggtttttcagctcttt gacaacgccaactgcccaagcctacagaacaaaccaaaaatgttcttcatccaggcctgc cgtggagatgagactgatcgtggggttgaccaacaagatggaaagaaccacgcaggatcc cctgggtgcgaggagagtgatgccggtaaagaaaagttgccgaagatgagactgcccacg cgctcagacatgatatgcggctatgcctgcctcaaagggactgccgccatgcggaacacc aaacgaggttcctggtacatcgaggctcttgctcaagtgttttctgagcgggcttgtgat atgcacgtggccgacatgctggttaaggtgaacgcacttatcaaggatcgggaaggttat gctcctggcacagaattccaccggtgcaaggagatgtctgaatactgcagcactctgtgc cgccacctctacctgttcccaggacaccctcccacatga |
Protein Sequence |
>835 : length: 452 MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHL LEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLT TLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKPCT PEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDV HVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLF DNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPT RSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVNALIKDREGY APGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT |