| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 835 |
Name | CASP2 |
Synonymous | CASP-2|ICH1|NEDD-2|NEDD2|PPP1R57;caspase 2, apoptosis-related cysteine peptidase;CASP2;caspase 2, apoptosis-related cysteine peptidase |
Definition | caspase-2|neural precursor cell expressed developmentally down-regulated protein 2|protease ICH-1|protein phosphatase 1, regulatory subunit 57 |
Position | 7q34-q35 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
in same component |
BIRC3 | NCI_NATURE; |
in same component |
CRADD | NCI_NATURE; |
in same component |
FADD | NCI_NATURE; |
in same component |
MAP3K5 | NCI_NATURE; |
in same component |
RIPK1 | NCI_NATURE; |
in same component |
TNF | NCI_NATURE; |
in same component |
TNFRSF1A | NCI_NATURE; |
in same component |
TRADD | NCI_NATURE; |
in same component |
TRAF1 | NCI_NATURE; |
in same component |
TRAF2 | NCI_NATURE; |
interacts with |
BID | BIOGRID; |
interacts with |
CASP10 | BIOGRID; |
interacts with |
CASP14 | BIOGRID; |
interacts with |
CASP3 | BIOGRID; |
interacts with |
CASP7 | BIOGRID; |
interacts with |
CASP8 | BIOGRID; |
interacts with |
CCND3 | BIOGRID; |
interacts with |
CRADD | BIOGRID; |
interacts with |
CRADD | CELL_MAP; |
interacts with |
CRADD | MINT; |
interacts with |
MDM2 | BIOGRID; |
interacts with |
NLRP1 | BIOGRID; |
interacts with |
NOD1 | BIOGRID; |
interacts with |
NOL3 | BIOGRID; |
interacts with |
PIDD | BIOGRID; |
interacts with |
TNFRSF1A | BIOGRID; |
Metabolic Interaction [Top] | ||
There is no record for CASP2 | ||
Signaling Interaction [Top] | ||
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
BAG4 | NCI_NATURE; |
reacts with |
BIRC3 | NCI_NATURE; |
reacts with |
CASP2 | NCI_NATURE; |
reacts with |
CRADD | NCI_NATURE; |
reacts with |
FADD | NCI_NATURE; |
reacts with |
MAP3K5 | NCI_NATURE; |
reacts with |
RIPK1 | NCI_NATURE; |
reacts with |
TNF | NCI_NATURE; |
reacts with |
TNFRSF1A | NCI_NATURE; |
reacts with |
TRADD | NCI_NATURE; |
reacts with |
TRAF1 | NCI_NATURE; |
reacts with |
TRAF2 | NCI_NATURE; |
state change |
BIRC3 | NCI_NATURE; |
state change |
CRADD | NCI_NATURE; |
state change |
MADD | NCI_NATURE; |
state change |
PIDD | NCI_NATURE; |
state change |
RIPK1 | NCI_NATURE; |
state change |
TNF | NCI_NATURE; |
state change |
TNFRSF1A | NCI_NATURE; |
state change |
TRADD | NCI_NATURE; |
state change |
TRAF2 | NCI_NATURE; |