General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 11200 |
Name | CHEK2 |
Synonymous | CDS1|CHK2|HuCds1|LFS2|PP1425|RAD53|hCds1;checkpoint kinase 2;CHEK2;checkpoint kinase 2 |
Definition | CHK2 checkpoint homolog|cds1 homolog|checkpoint-like protein CHK2|serine/threonine-protein kinase Chk2 |
Position | 22q12.1 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
interacts with |
AATF | HPRD; |
interacts with |
ASF1A | HPRD; |
interacts with |
ATM | BIOGRID; |
interacts with |
ATM | HPRD; |
interacts with |
ATM | MINT; |
interacts with |
ATR | BIOGRID; |
interacts with |
ATR | HPRD; |
interacts with |
BRCA1 | BIOGRID; |
interacts with |
BRCA2 | BIOGRID; |
interacts with |
CDC25A | BIOGRID; |
interacts with |
CDC25A | HPRD; |
interacts with |
CDC25A | MINT; |
interacts with |
CDC25C | BIOGRID; |
interacts with |
CDC25C | HPRD; |
interacts with |
CHEK1 | HPRD; |
interacts with |
DBF4 | HPRD; |
interacts with |
E2F1 | HPRD; |
interacts with |
ERCC6 | HPRD; |
interacts with |
FOXM1 | BIOGRID; |
interacts with |
GINS2 | BIOGRID; |
interacts with |
KPNA2 | HPRD; |
interacts with |
KPNA2 | MINT; |
interacts with |
MDC1 | BIOGRID; |
interacts with |
MDC1 | HPRD; |
interacts with |
MDM2 | BIOGRID; |
interacts with |
MDM2 | HPRD; |
interacts with |
MDM2 | MINT; |
interacts with |
MDM4 | BIOGRID; |
interacts with |
MDM4 | HPRD; |
interacts with |
MRC1 | HPRD; |
interacts with |
MSH2 | BIOGRID; |
interacts with |
MSH2 | HPRD; |
interacts with |
MUS81 | BIOGRID; |
interacts with |
MUS81 | HPRD; |
interacts with |
NBN | HPRD; |
interacts with |
NBN | MINT; |
interacts with |
PER3 | MINT; |
interacts with |
PLK1 | BIOGRID; |
interacts with |
PLK1 | HPRD; |
interacts with |
PLK3 | BIOGRID; |
interacts with |
PLK3 | HPRD; |
interacts with |
PPP2R2A | HPRD; |
interacts with |
PPP2R5A | HPRD; |
interacts with |
PPP2R5B | HPRD; |
interacts with |
PPP2R5D | HPRD; |
interacts with |
PPP2R5E | HPRD; |
interacts with |
RAD50 | BIOGRID; |
interacts with |
RAD9A | HPRD; |
interacts with |
RB1 | MINT; |
interacts with |
REV3L | BIOGRID; |
interacts with |
STRAP | MINT; |
interacts with |
TP53BP1 | BIOGRID; |
interacts with |
TP53 | BIOGRID; |
interacts with |
TP53 | MINT; |
interacts with |
VCP | BIOGRID; |
interacts with |
XRCC1 | MINT; |
Metabolic Interaction [Top] | ||
There is no record for CHEK2 |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
state change |
ATM | NCI_NATURE; |
state change |
BRCA1 | NCI_NATURE; |
state change |
H2AFX | NCI_NATURE; |
state change |
MDC1 | NCI_NATURE; |
state change |
MRE11A | NCI_NATURE; |
state change |
NBN | NCI_NATURE; |
state change |
PLK3 | NCI_NATURE; |
state change |
RAD50 | NCI_NATURE; |
state change |
RNF8 | NCI_NATURE; |
state change |
TP53BP1 | NCI_NATURE; |