Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

22943

Name

DKK1

Synonymous

DKK-1|SK;dickkopf WNT signaling pathway inhibitor 1;DKK1;dickkopf WNT signaling pathway inhibitor 1

Definition

dickkopf 1 homolog|dickkopf related protein-1|dickkopf-1 like|dickkopf-like protein 1|dickkopf-related protein 1|hDkk-1

Position

10q11.2

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 KREMEN2NCI_NATURE;

in same component

 LRP5NCI_NATURE;

in same component

 LRP6NCI_NATURE;

interacts with

 CORO1ABIOGRID;

interacts with

 DKK2NCI_NATURE;

interacts with

 KREMEN1HPRD;

interacts with

 KREMEN2NCI_NATURE;

interacts with

 LRP5CELL_MAP;

interacts with

 LRP5HPRD;

interacts with

 LRP6BIOGRID;

interacts with

 LRP6CELL_MAP;

interacts with

 LRP6HPRD;

interacts with

 LRP6NCI_NATURE;

interacts with

 MDFIBIOGRID;

interacts with

 MDFIHPRD;

interacts with

 MDFIMINT;

interacts with

 SMAD9HPRD;

interacts with

 SMAD9MINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 CTNNB1NCI_NATURE;

metabolic catalysis

 HDAC2NCI_NATURE;

metabolic catalysis

 MAXNCI_NATURE;

metabolic catalysis

 MED12NCI_NATURE;

metabolic catalysis

 MYCNCI_NATURE;

metabolic catalysis

 TCF7L2NCI_NATURE;

metabolic catalysis

 TP53NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 DKK1NCI_NATURE;

reacts with

 DKK2NCI_NATURE;

reacts with

 FZD1NCI_NATURE;

reacts with

 FZD8NCI_NATURE;

reacts with

 KREMEN2NCI_NATURE;

reacts with

 LRP5NCI_NATURE;

reacts with

 LRP6NCI_NATURE;

reacts with

 WNT1NCI_NATURE;

reacts with

 WNT3ANCI_NATURE;

state change

 RSPO1NCI_NATURE;

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