Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5925

Name

RB1

Synonymous

OSRC|PPP1R130|RB|p105-Rb|pRb|pp110;retinoblastoma 1;RB1;retinoblastoma 1

Definition

prepro-retinoblastoma-associated protein|protein phosphatase 1, regulatory subunit 130|retinoblastoma suspectibility protein|retinoblastoma-associated protein

Position

13q14.2

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 AATFNCI_NATURE;

in same component

 ABL1NCI_NATURE;

in same component

 CBX4NCI_NATURE;

in same component

 CDK2REACTOME;

in same component

 CEBPANCI_NATURE;

in same component

 CTBP1NCI_NATURE;

in same component

 DNMT1NCI_NATURE;

in same component

 E2F1NCI_NATURE;

in same component

 E2F1REACTOME;

in same component

 E2F4NCI_NATURE;

in same component

 ELF1NCI_NATURE;

in same component

 HDAC1NCI_NATURE;

in same component

 HDAC3NCI_NATURE;

in same component

 HES1NCI_NATURE;

in same component

 JUNNCI_NATURE;

in same component

 PPARGNCI_NATURE;

in same component

 RBBP4NCI_NATURE;

in same component

 RUNX2NCI_NATURE;

in same component

 SKP2NCI_NATURE;

in same component

 SMARCA2NCI_NATURE;

in same component

 SPI1NCI_NATURE;

in same component

 SUV39H1NCI_NATURE;

in same component

 TFDP1NCI_NATURE;

in same component

 TFDP1REACTOME;

interacts with

 AATFBIOGRID;

interacts with

 AATFHPRD;

interacts with

 ABL1BIOGRID;

interacts with

 AHRBIOGRID;

interacts with

 AHRHPRD;

interacts with

 APC2HPRD;

interacts with

 ARID3BBIOGRID;

interacts with

 ARID3BHPRD;

interacts with

 ARID4ABIOGRID;

interacts with

 ARNTBIOGRID;

interacts with

 ARBIOGRID;

interacts with

 ARCELL_MAP;

interacts with

 ARHPRD;

interacts with

 ATF2BIOGRID;

interacts with

 ATF2HPRD;

interacts with

 AURKBBIOGRID;

interacts with

 BAG1BIOGRID;

interacts with

 BAG1HPRD;

interacts with

 BDP1HPRD;

interacts with

 BNC2HPRD;

interacts with

 BRCA1BIOGRID;

interacts with

 BRF1BIOGRID;

interacts with

 BRF1HPRD;

interacts with

 CASP10HPRD;

interacts with

 CASP3HPRD;

interacts with

 CASP6HPRD;

interacts with

 CASP7HPRD;

interacts with

 CASP8HPRD;

interacts with

 CASP9HPRD;

interacts with

 CBX1BIOGRID;

interacts with

 CBX4BIOGRID;

interacts with

 CBX4HPRD;

interacts with

 CBX5BIOGRID;

interacts with

 CCNA1BIOGRID;

interacts with

 CCNA2HPRD;

interacts with

 CCND1BIOGRID;

interacts with

 CCND1HPRD;

interacts with

 CCND2HPRD;

interacts with

 CCND3BIOGRID;

interacts with

 CCNT2BIOGRID;

interacts with

 CCNT2HPRD;

interacts with

 CDC27HPRD;

interacts with

 CDK14HPRD;

interacts with

 CDK2BIOGRID;

interacts with

 CDK2HPRD;

interacts with

 CDK2INTACT;

interacts with

 CDK4BIOGRID;

interacts with

 CDK4HPRD;

interacts with

 CDK6HPRD;

interacts with

 CDK9BIOGRID;

interacts with

 CDK9HPRD;

interacts with

 CDKN1AHPRD;

interacts with

 CEBPAHPRD;

interacts with

 CEBPBBIOGRID;

interacts with

 CEBPBHPRD;

interacts with

 CEBPDHPRD;

interacts with

 CEBPEHPRD;

interacts with

 CHEK1MINT;

interacts with

 CHEK2MINT;

interacts with

 CREG1BIOGRID;

interacts with

 CREG1HPRD;

interacts with

 CTBP1HPRD;

interacts with

 CUX1BIOGRID;

interacts with

 CUX1HPRD;

interacts with

 CUX1MINT;

interacts with

 DGKZHPRD;

interacts with

 DHFRHPRD;

interacts with

 DNAJA2BIOGRID;

interacts with

 DNMT1BIOGRID;

interacts with

 DNMT1HPRD;

interacts with

 DNMT3ABIOGRID;

interacts with

 E2F1BIOGRID;

interacts with

 E2F1HPRD;

interacts with

 E2F1INTACT;

interacts with

 E2F1MINT;

interacts with

 E2F2BIOGRID;

interacts with

 E2F2HPRD;

interacts with

 E2F2MINT;

interacts with

 E2F3MINT;

interacts with

 E2F4BIOGRID;

interacts with

 E2F4CELL_MAP;

interacts with

 E2F4HPRD;

interacts with

 E4F1BIOGRID;

interacts with

 E4F1HPRD;

interacts with

 EID1BIOGRID;

interacts with

 EID1HPRD;

interacts with

 ELF1HPRD;

interacts with

 ENC1BIOGRID;

interacts with

 ENC1HPRD;

interacts with

 EP300HPRD;

interacts with

 FOXM1BIOGRID;

interacts with

 FRKBIOGRID;

interacts with

 FRKHPRD;

interacts with

 FZR1HPRD;

interacts with

 GTF3C2HPRD;

interacts with

 HBP1BIOGRID;

interacts with

 HBP1HPRD;

interacts with

 HDAC1BIOGRID;

interacts with

 HDAC1MINT;

interacts with

 HDAC2BIOGRID;

interacts with

 HDAC2HPRD;

interacts with

 HDAC2MINT;

interacts with

 HDAC3BIOGRID;

interacts with

 HDAC3HPRD;

interacts with

 HIST1H1BHPRD;

interacts with

 HMGA2BIOGRID;

interacts with

 HMGB1BIOGRID;

interacts with

 HMGB1HPRD;

interacts with

 HSPA8HPRD;

interacts with

 ID2CELL_MAP;

interacts with

 ID2HPRD;

interacts with

 Ifi205bMINT;

interacts with

 INSHPRD;

interacts with

 JUNBIOGRID;

interacts with

 JUNHPRD;

interacts with

 KAT2BBIOGRID;

interacts with

 KDM1ABIOGRID;

interacts with

 KDM4ABIOGRID;

interacts with

 KDM5ABIOGRID;

interacts with

 KDM5AHPRD;

interacts with

 KDM5BBIOGRID;

interacts with

 KDM5BHPRD;

interacts with

 L3MBTL1BIOGRID;

interacts with

 L3MBTL1HPRD;

interacts with

 L3MBTL2BIOGRID;

interacts with

 LIN54BIOGRID;

interacts with

 LIN9BIOGRID;

interacts with

 LIN9HPRD;

interacts with

 LMNABIOGRID;

interacts with

 LMNAHPRD;

interacts with

 LMO2HPRD;

interacts with

 MAPK14INTACT;

interacts with

 MAPK14MINT;

interacts with

 MAPK1HPRD;

interacts with

 MAPK9HPRD;

interacts with

 mcl1MINT;

interacts with

 MCM7BIOGRID;

interacts with

 MCM7MINT;

interacts with

 MDM2BIOGRID;

interacts with

 MDM2HPRD;

interacts with

 MDM2INTACT;

interacts with

 MDM2MINT;

interacts with

 MDM4HPRD;

interacts with

 MDM4MINT;

interacts with

 MNAT1BIOGRID;

interacts with

 MNAT1HPRD;

interacts with

 MNDAHPRD;

interacts with

 MORF4L1BIOGRID;

interacts with

 MORF4L1HPRD;

interacts with

 MORF4L2BIOGRID;

interacts with

 MORF4L2HPRD;

interacts with

 MRFAP1BIOGRID;

interacts with

 MRFAP1HPRD;

interacts with

 MTBPHPRD;

interacts with

 MYCBIOGRID;

interacts with

 MYCHPRD;

interacts with

 MYOD1BIOGRID;

interacts with

 MYOD1HPRD;

interacts with

 NCOA6BIOGRID;

interacts with

 NCOA6HPRD;

interacts with

 NFIXBIOGRID;

interacts with

 PA2G4BIOGRID;

interacts with

 PA2G4HPRD;

interacts with

 PAX2HPRD;

interacts with

 PAX6BIOGRID;

interacts with

 PELP1BIOGRID;

interacts with

 PELP1HPRD;

interacts with

 PHBBIOGRID;

interacts with

 PHBHPRD;

interacts with

 PIK3R1HPRD;

interacts with

 PIK3R3BIOGRID;

interacts with

 PIK3R3HPRD;

interacts with

 POLA1BIOGRID;

interacts with

 POLA1HPRD;

interacts with

 PPA1BIOGRID;

interacts with

 PPARGBIOGRID;

interacts with

 PPIAHPRD;

interacts with

 PPP1CAHPRD;

interacts with

 PPP1CBHPRD;

interacts with

 PPP1CCHPRD;

interacts with

 PRDM2BIOGRID;

interacts with

 PRDM2HPRD;

interacts with

 PRKCBHPRD;

interacts with

 PRKRABIOGRID;

interacts with

 PRKRAHPRD;

interacts with

 PRMT2HPRD;

interacts with

 PSMD10HPRD;

interacts with

 PURAHPRD;

interacts with

 RAF1BIOGRID;

interacts with

 RAF1HPRD;

interacts with

 RAF1INTACT;

interacts with

 RBAKHPRD;

interacts with

 RBBP4BIOGRID;

interacts with

 RBBP4HPRD;

interacts with

 RBBP5BIOGRID;

interacts with

 RBBP5HPRD;

interacts with

 RBBP7BIOGRID;

interacts with

 RBBP8BIOGRID;

interacts with

 RBBP8HPRD;

interacts with

 RBBP8MINT;

interacts with

 RBBP9BIOGRID;

interacts with

 RBBP9HPRD;

interacts with

 RBL1BIOGRID;

interacts with

 RBL1HPRD;

interacts with

 RBL2BIOGRID;

interacts with

 RFC1BIOGRID;

interacts with

 RING1BIOGRID;

interacts with

 RING1HPRD;

interacts with

 RNF40HPRD;

interacts with

 RUNX2HPRD;

interacts with

 SERPINB2BIOGRID;

interacts with

 SERPINB2HPRD;

interacts with

 Sin3aBIOGRID;

interacts with

 SKILBIOGRID;

interacts with

 SKIBIOGRID;

interacts with

 SKP2BIOGRID;

interacts with

 SKP2HPRD;

interacts with

 Smarca4BIOGRID;

interacts with

 SMARCA4BIOGRID;

interacts with

 SMYD2BIOGRID;

interacts with

 SNAPC1BIOGRID;

interacts with

 SNAPC1HPRD;

interacts with

 SNAPC3BIOGRID;

interacts with

 SNAPC3HPRD;

interacts with

 SNW1BIOGRID;

interacts with

 SNW1HPRD;

interacts with

 SP1BIOGRID;

interacts with

 SP1HPRD;

interacts with

 SP3HPRD;

interacts with

 SPI1HPRD;

interacts with

 SPIBHPRD;

interacts with

 STAT3BIOGRID;

interacts with

 SUV39H1BIOGRID;

interacts with

 SUV39H1HPRD;

interacts with

 SUV420H2HPRD;

interacts with

 TAF1BIOGRID;

interacts with

 TAF1HPRD;

interacts with

 TBPBIOGRID;

interacts with

 TBPHPRD;

interacts with

 TCF3HPRD;

interacts with

 TFAP2AHPRD;

interacts with

 TFDP1BIOGRID;

interacts with

 TFDP2BIOGRID;

interacts with

 TGM2BIOGRID;

interacts with

 TGM2HPRD;

interacts with

 THOC1BIOGRID;

interacts with

 THOC1HPRD;

interacts with

 TMPOBIOGRID;

interacts with

 TMPOHPRD;

interacts with

 TOP2AHPRD;

interacts with

 TP53INTACT;

interacts with

 TP73BIOGRID;

interacts with

 TRAP1BIOGRID;

interacts with

 TRAP1HPRD;

interacts with

 TRIM27HPRD;

interacts with

 TRIP11BIOGRID;

interacts with

 TRIP11HPRD;

interacts with

 UBTFBIOGRID;

interacts with

 UBTFHPRD;

interacts with

 USP4BIOGRID;

interacts with

 USP4HPRD;

interacts with

 VDRBIOGRID;

interacts with

 YY1BIOGRID;

interacts with

 ZBTB16HPRD;

interacts with

 ZBTB7ABIOGRID;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 ATF2NCI_NATURE;

metabolic catalysis

 E2F1NCI_NATURE;

metabolic catalysis

 TP53NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 AATFNCI_NATURE;

reacts with

 ABL1NCI_NATURE;

reacts with

 CBX4NCI_NATURE;

reacts with

 CDK2REACTOME;

reacts with

 CDKN1BNCI_NATURE;

reacts with

 CEBPANCI_NATURE;

reacts with

 CTBP1NCI_NATURE;

reacts with

 DNMT1NCI_NATURE;

reacts with

 E2F1REACTOME;

reacts with

 E2F4NCI_NATURE;

reacts with

 ELF1NCI_NATURE;

reacts with

 GSCNCI_NATURE;

reacts with

 HDAC1NCI_NATURE;

reacts with

 HDAC3NCI_NATURE;

reacts with

 HES1NCI_NATURE;

reacts with

 JUNNCI_NATURE;

reacts with

 PPARGNCI_NATURE;

reacts with

 RB1NCI_NATURE;

reacts with

 RB1REACTOME;

reacts with

 RBBP4NCI_NATURE;

reacts with

 RUNX2NCI_NATURE;

reacts with

 SKP2NCI_NATURE;

reacts with

 SMARCA2NCI_NATURE;

reacts with

 SPI1NCI_NATURE;

reacts with

 SUV39H1NCI_NATURE;

reacts with

 TFDP1NCI_NATURE;

reacts with

 TFDP1REACTOME;

state change

 CASP3IMID;

state change

 CCNA2NCI_NATURE;

state change

 CCND1CELL_MAP;

state change

 CCND1NCI_NATURE;

state change

 CCNE1NCI_NATURE;

state change

 CDK2NCI_NATURE;

state change

 CDK2REACTOME;

state change

 CDK4CELL_MAP;

state change

 CDK4NCI_NATURE;

state change

 CDK6CELL_MAP;

state change

 CDKN1ANCI_NATURE;

state change

 PPP2CANCI_NATURE;

state change

 PPP2R3BNCI_NATURE;

state change

 RAF1NCI_NATURE;

state change

 RB1REACTOME;

state change

 SIRT1NCI_NATURE;

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