General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 6850 |
Name | SYK |
Synonymous | p72-Syk;spleen tyrosine kinase;SYK;spleen tyrosine kinase |
Definition | tyrosine-protein kinase SYK |
Position | 9q22 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
APBB1IP | REACTOME; |
in same component |
BLNK | NCI_NATURE; |
in same component |
BTK | NCI_NATURE; |
in same component |
CD72 | NCI_NATURE; |
in same component |
CD79A | NCI_NATURE; |
in same component |
CD79B | NCI_NATURE; |
in same component |
CSF2RA | NCI_NATURE; |
in same component |
CSF2RB | NCI_NATURE; |
in same component |
CSF2 | NCI_NATURE; |
in same component |
FASLG | NCI_NATURE; |
in same component |
FAS | NCI_NATURE; |
in same component |
FCER1A | NCI_NATURE; |
in same component |
FCER1G | NCI_NATURE; |
in same component |
FCER1G | REACTOME; |
in same component |
FYN | REACTOME; |
in same component |
GP6 | REACTOME; |
in same component |
IGHE | NCI_NATURE; |
in same component |
IL2RA | NCI_NATURE; |
in same component |
IL2RA | REACTOME; |
in same component |
IL2RB | NCI_NATURE; |
in same component |
IL2RB | REACTOME; |
in same component |
IL2RG | NCI_NATURE; |
in same component |
IL2RG | REACTOME; |
in same component |
IL2 | NCI_NATURE; |
in same component |
IL2 | REACTOME; |
in same component |
ITGA2B | REACTOME; |
in same component |
ITGB3 | REACTOME; |
in same component |
JAK1 | NCI_NATURE; |
in same component |
JAK1 | REACTOME; |
in same component |
JAK3 | NCI_NATURE; |
in same component |
JAK3 | REACTOME; |
in same component |
LCK | NCI_NATURE; |
in same component |
LYN | IMID; |
in same component |
LYN | NCI_NATURE; |
in same component |
LYN | REACTOME; |
in same component |
MS4A2 | NCI_NATURE; |
in same component |
PLCG2 | NCI_NATURE; |
in same component |
SRC | NCI_NATURE; |
in same component |
TLN1 | REACTOME; |
in same component |
WIPF1 | NCI_NATURE; |
interacts with |
BLNK | HPRD; |
interacts with |
BLNK | MINT; |
interacts with |
BTK | HPRD; |
interacts with |
CBLB | BIOGRID; |
interacts with |
CBLB | HPRD; |
interacts with |
CBL | BIOGRID; |
interacts with |
CBL | HPRD; |
interacts with |
CBL | MINT; |
interacts with |
CD19 | BIOGRID; |
interacts with |
CD19 | HPRD; |
interacts with |
CD22 | BIOGRID; |
interacts with |
CD3E | BIOGRID; |
interacts with |
CD3E | HPRD; |
interacts with |
CD3E | MINT; |
interacts with |
CD4 | BIOGRID; |
interacts with |
CD72 | BIOGRID; |
interacts with |
CD79A | BIOGRID; |
interacts with |
CD79A | HPRD; |
interacts with |
CD79B | BIOGRID; |
interacts with |
CD79B | HPRD; |
interacts with |
CRKL | BIOGRID; |
interacts with |
CRKL | HPRD; |
interacts with |
CSF2RB | HPRD; |
interacts with |
CSF3R | BIOGRID; |
interacts with |
CSF3R | HPRD; |
interacts with |
CTTN | BIOGRID; |
interacts with |
CTTN | HPRD; |
interacts with |
DBNL | HPRD; |
interacts with |
DUSP3 | HPRD; |
interacts with |
EGFR | MINT; |
interacts with |
EPOR | BIOGRID; |
interacts with |
EPOR | HPRD; |
interacts with |
ERBB2 | MINT; |
interacts with |
ERBB3 | MINT; |
interacts with |
ERBB4 | MINT; |
interacts with |
FCER1G | BIOGRID; |
interacts with |
FCER1G | HPRD; |
interacts with |
Fcer1g | MINT; |
interacts with |
FCER1G | MINT; |
interacts with |
FCGR1A | HPRD; |
interacts with |
FCGR2A | BIOGRID; |
interacts with |
FCGR2A | HPRD; |
interacts with |
FCGR2A | MINT; |
interacts with |
FCRL3 | BIOGRID; |
interacts with |
FGR | BIOGRID; |
interacts with |
FGR | MINT; |
interacts with |
FYN | BIOGRID; |
interacts with |
FYN | HPRD; |
interacts with |
GAB2 | HPRD; |
interacts with |
HCLS1 | HPRD; |
interacts with |
HDAC1 | BIOGRID; |
interacts with |
HDAC2 | BIOGRID; |
interacts with |
HDAC3 | BIOGRID; |
interacts with |
HDAC4 | BIOGRID; |
interacts with |
HDAC6 | BIOGRID; |
interacts with |
HDAC9 | BIOGRID; |
interacts with |
HNRNPU | HPRD; |
interacts with |
IL15RA | HPRD; |
interacts with |
IL2RB | HPRD; |
interacts with |
ITGB2 | BIOGRID; |
interacts with |
ITGB2 | HPRD; |
interacts with |
JAK1 | HPRD; |
interacts with |
LAT | BIOGRID; |
interacts with |
LAT | HPRD; |
interacts with |
LAX1 | HPRD; |
interacts with |
LCK | BIOGRID; |
interacts with |
LCK | HPRD; |
interacts with |
LCK | MINT; |
interacts with |
LCP2 | HPRD; |
interacts with |
LYN | BIOGRID; |
interacts with |
LYN | HPRD; |
interacts with |
MAP4K1 | HPRD; |
interacts with |
MAPK3 | HPRD; |
interacts with |
MS4A2 | BIOGRID; |
interacts with |
MS4A2 | HPRD; |
interacts with |
MSN | MINT; |
interacts with |
NFAM1 | HPRD; |
interacts with |
Nfam1 | MINT; |
interacts with |
PAG1 | BIOGRID; |
interacts with |
PAG1 | HPRD; |
interacts with |
PIK3AP1 | HPRD; |
interacts with |
PIK3R1 | HPRD; |
interacts with |
PIK3R1 | MINT; |
interacts with |
PIK3R2 | HPRD; |
interacts with |
PIK3R2 | MINT; |
interacts with |
PLCG1 | BIOGRID; |
interacts with |
PLCG1 | MINT; |
interacts with |
PLCG2 | BIOGRID; |
interacts with |
PLCG2 | HPRD; |
interacts with |
POU2AF1 | HPRD; |
interacts with |
PRKCA | HPRD; |
interacts with |
PRKD1 | BIOGRID; |
interacts with |
PRKD1 | HPRD; |
interacts with |
PTK2B | BIOGRID; |
interacts with |
PTK2B | HPRD; |
interacts with |
PTK2 | BIOGRID; |
interacts with |
PTPN6 | BIOGRID; |
interacts with |
PTPN6 | HPRD; |
interacts with |
PXN | BIOGRID; |
interacts with |
PXN | HPRD; |
interacts with |
RASA1 | HPRD; |
interacts with |
RPS6KA1 | HPRD; |
interacts with |
RPS6KB1 | BIOGRID; |
interacts with |
RPS6KB2 | BIOGRID; |
interacts with |
SELPLG | HPRD; |
interacts with |
SH2B2 | HPRD; |
interacts with |
SH3BP2 | BIOGRID; |
interacts with |
SH3BP2 | HPRD; |
interacts with |
SH3BP2 | MINT; |
interacts with |
SHC1 | HPRD; |
interacts with |
SIRPB1 | BIOGRID; |
interacts with |
SIT1 | BIOGRID; |
interacts with |
SIT1 | HPRD; |
interacts with |
SLA | BIOGRID; |
interacts with |
SLA | HPRD; |
interacts with |
SLC4A1 | HPRD; |
interacts with |
SNCA | HPRD; |
interacts with |
SP1 | BIOGRID; |
interacts with |
SRC | BIOGRID; |
interacts with |
SRC | HPRD; |
interacts with |
STAT1 | HPRD; |
interacts with |
STAT3 | HPRD; |
interacts with |
STAT5A | HPRD; |
interacts with |
TNFRSF1A | HPRD; |
interacts with |
TRAF6 | BIOGRID; |
interacts with |
TRAF6 | HPRD; |
interacts with |
TUBA1A | BIOGRID; |
interacts with |
TUBA1A | HPRD; |
interacts with |
TUBA4A | HPRD; |
interacts with |
TYROBP | HPRD; |
interacts with |
VAV1 | BIOGRID; |
interacts with |
VAV1 | HPRD; |
interacts with |
VAV1 | MINT; |
interacts with |
VAV2 | HPRD; |
interacts with |
VAV2 | MINT; |
Metabolic Interaction [Top] | ||
There is no record for SYK |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
APBB1IP | REACTOME; |
reacts with |
BLNK | NCI_NATURE; |
reacts with |
BTK | NCI_NATURE; |
reacts with |
CD72 | NCI_NATURE; |
reacts with |
CD79A | NCI_NATURE; |
reacts with |
CD79B | NCI_NATURE; |
reacts with |
CSF2RA | NCI_NATURE; |
reacts with |
CSF2RB | NCI_NATURE; |
reacts with |
CSF2 | NCI_NATURE; |
reacts with |
FASLG | NCI_NATURE; |
reacts with |
FAS | NCI_NATURE; |
reacts with |
FCER1A | NCI_NATURE; |
reacts with |
FCER1G | NCI_NATURE; |
reacts with |
FCER1G | REACTOME; |
reacts with |
FYN | REACTOME; |
reacts with |
GP6 | REACTOME; |
reacts with |
IGHE | NCI_NATURE; |
reacts with |
IL2RA | NCI_NATURE; |
reacts with |
IL2RA | REACTOME; |
reacts with |
IL2RB | NCI_NATURE; |
reacts with |
IL2RB | REACTOME; |
reacts with |
IL2RG | NCI_NATURE; |
reacts with |
IL2RG | REACTOME; |
reacts with |
IL2 | NCI_NATURE; |
reacts with |
IL2 | REACTOME; |
reacts with |
ITGA2B | REACTOME; |
reacts with |
ITGB3 | REACTOME; |
reacts with |
JAK1 | NCI_NATURE; |
reacts with |
JAK1 | REACTOME; |
reacts with |
JAK3 | NCI_NATURE; |
reacts with |
JAK3 | REACTOME; |
reacts with |
LCK | NCI_NATURE; |
reacts with |
LCP2 | REACTOME; |
reacts with |
LYN | IMID; |
reacts with |
LYN | NCI_NATURE; |
reacts with |
LYN | REACTOME; |
reacts with |
MS4A2 | NCI_NATURE; |
reacts with |
PIK3CB | REACTOME; |
reacts with |
PIK3CG | REACTOME; |
reacts with |
PLCG2 | NCI_NATURE; |
reacts with |
PTPN6 | NCI_NATURE; |
reacts with |
SRC | NCI_NATURE; |
reacts with |
SYK | IMID; |
reacts with |
SYK | NCI_NATURE; |
reacts with |
SYK | REACTOME; |
reacts with |
TLN1 | REACTOME; |
reacts with |
WIPF1 | NCI_NATURE; |
state change |
APBB1IP | REACTOME; |
state change |
FCER1G | REACTOME; |
state change |
FYN | REACTOME; |
state change |
GP6 | REACTOME; |
state change |
IBTK | NCI_NATURE; |
state change |
IL2RA | REACTOME; |
state change |
IL2RB | REACTOME; |
state change |
IL2RG | REACTOME; |
state change |
IL2 | REACTOME; |
state change |
ITGA2B | REACTOME; |
state change |
ITGAV | NCI_NATURE; |
state change |
ITGB3 | NCI_NATURE; |
state change |
ITGB3 | REACTOME; |
state change |
JAK1 | REACTOME; |
state change |
JAK3 | REACTOME; |
state change |
KLRG1 | NCI_NATURE; |
state change |
LYN | REACTOME; |
state change |
PTPN11 | NCI_NATURE; |
state change |
PTPN6 | NCI_NATURE; |
state change |
SH3BP5 | NCI_NATURE; |
state change |
SPP1 | NCI_NATURE; |
state change |
SRC | IMID; |
state change |
SYK | REACTOME; |
state change |
TLN1 | REACTOME; |