Entrez Gene

Basic Information
Gene ID	4089
Name	SMAD4
Synonymous	SMAD family member 4;SMAD4;SMAD family member 4
Definition	MAD homolog 4\|SMAD, mothers against DPP homolog 4\|deleted in pancreatic carcinoma locus 4\|deletion target in pancreatic carcinoma 4\|mothers against decapentaplegic homolog 4\|mothers against decapentaplegic, Drosophila, homolog of, 4
Position	18q21.1
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Loss of Function mutations compare to missense mutations

Top

The ratio of the loss-of-function mutations over missense mutations is 0.33.

The copy number variations for various cancers

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.68T>G; p.L23W; 18:51047114-51047114	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.68T>G; p.L23W; 18:51047114-51047114	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.741A>G; p.G247G; 18:51058198-51058198	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.68T>G; p.L23W; 18:51047114-51047114	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.68T>G; p.L23W; 18:51047114-51047114	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.68T>G; p.L23W; 18:51047114-51047114	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.68T>G; p.L23W; 18:51047114-51047114	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.68T>G; p.L23W; 18:51047114-51047114	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1547A>G; p.Q516R; 18:51078355-51078355	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1547A>G; p.Q516R; 18:51078355-51078355	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1321C>A; p.R441S; 18:51076650-51076650	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.322G>T; p.E108*; 18:51048758-51048758	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1321C>A; p.R441S; 18:51076650-51076650	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1658G>C; p.*553S; 18:51078466-51078466	pancreas	carcinoma	Nonstop extension
c.310C>T; p.L104F; 18:51048746-51048746	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.247C>T; p.Q83*; 18:51047293-51047293	pancreas	NS	Substitution - Nonsense
c.247C>T; p.Q83*; 18:51047293-51047293	breast	carcinoma; lobular_carcinoma	Substitution - Nonsense
c.1294A>G; p.S432G; 18:51067173-51067173	thyroid	adenoma-nodule-goitre	Substitution - Missense
c.1479T>C; p.D493D; 18:51078287-51078287	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.745C>T; p.Q249*; 18:51058202-51058202	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1049T>C; p.V350A; 18:51065516-51065516	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.439_440delAC; p.L148fs*3; 18:51049309-51049310	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1260T>C; p.R420R; 18:51067139-51067139	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.439_440delAC; p.L148fs*3; 18:51049309-51049310	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1613A>G; p.E538G; 18:51078421-51078421	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.989A>G; p.E330G; 18:51065456-51065456	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.431C>G; p.S144*; 18:51049301-51049301	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.431C>G; p.S144*; 18:51049301-51049301	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.431C>G; p.S144*; 18:51049301-51049301	breast	carcinoma	Substitution - Nonsense
c.1247G>T; p.R416I; 18:51067126-51067126	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1064A>G; p.D355G; 18:51065531-51065531	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1055G>T; p.G352V; 18:51065522-51065522	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1579A>G; p.I527V; 18:51078387-51078387	thyroid	adenoma-nodule-goitre; Hurthle_cell_adenoma	Substitution - Missense
c.1055G>T; p.G352V; 18:51065522-51065522	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1064A>G; p.D355G; 18:51065531-51065531	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1055G>T; p.G352V; 18:51065522-51065522	pancreas	carcinoma	Substitution - Missense
c.1064A>G; p.D355G; 18:51065531-51065531	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.585C>A; p.Y195*; 18:51054911-51054911	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1055G>T; p.G352V; 18:51065522-51065522	pancreas	carcinoma	Substitution - Missense
c.1064A>G; p.D355G; 18:51065531-51065531	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1055G>T; p.G352V; 18:51065522-51065522	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1579A>G; p.I527V; 18:51078387-51078387	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1064A>G; p.D355G; 18:51065531-51065531	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1016T>A; p.F339Y; 18:51065483-51065483	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>T; p.G386V; 18:51067036-51067036	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1139G>A; p.R380K; 18:51065606-51065606	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>T; p.G386V; 18:51067036-51067036	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>T; p.G386V; 18:51067036-51067036	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>T; p.G386V; 18:51067036-51067036	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1157G>T; p.G386V; 18:51067036-51067036	small_intestine; jejunum	carcinoma; adenocarcinoma	Substitution - Missense
c.440C>T; p.T147I; 18:51049310-51049310	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1016T>C; p.F339S; 18:51065483-51065483	thyroid	carcinoma; Hurthle_cell_carcinoma	Substitution - Missense
c.1482C>T; p.D494D; 18:51078290-51078290	thyroid	carcinoma; papillary_carcinoma	Substitution - coding silent
c.1648_1659del12; p.?; 18:51078456-51078485	large_intestine; appendix	carcinoma; adenocarcinoma	Unknown
c.1619T>G; p.L540R; 18:51078427-51078427	pancreas	carcinoma	Substitution - Missense
c.1619T>G; p.L540R; 18:51078427-51078427	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1619T>G; p.L540R; 18:51078427-51078427	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1648C>T; p.P550S; 18:51078456-51078456	thyroid	carcinoma; papillary_carcinoma	Substitution - Missense
c.1619T>G; p.L540R; 18:51078427-51078427	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1619T>G; p.L540R; 18:51078427-51078427	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1301_1302insT; p.I435fs*5; 18:51067180-51067181	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.1619T>G; p.L540R; 18:51078427-51078427	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1020G>C; p.K340N; 18:51065487-51065487	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1619T>G; p.L540R; 18:51078427-51078427	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1619T>G; p.L540R; 18:51078427-51078427	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1020G>C; p.K340N; 18:51065487-51065487	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1_1659del1659; p.0?; 18:51047047-51078467	breast	carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.382G>A; p.V128M; 18:51048818-51048818	thyroid	adenoma-nodule-goitre; Hurthle_cell_adenoma	Substitution - Missense
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.437T>G; p.L146*; 18:51049307-51049307	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	large_intestine	carcinoma; adenocarcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1129_1130delGA; p.R378fs*14; 18:51065596-51065597	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1514T>A; p.F505Y; 18:51078322-51078322	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	stomach	carcinoma; adenocarcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	breast	carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	oesophagus	carcinoma; adenocarcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1_1659del1659; p.0?; 18:51047047-51078467	pancreas	carcinoma; ductal_carcinoma	Whole gene deletion
c.1242_1245delAGAC; p.D415fs*20; 18:51067121-51067124	stomach	carcinoma; diffuse_adenocarcinoma	Deletion - Frameshift
c.1258C>T; p.R420C; 18:51067137-51067137	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.633T>C; p.T211T; 18:51054959-51054959	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - coding silent
c.690G>T; p.G230G; 18:51058147-51058147	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1242_1245delAGAC; p.D415fs*20; 18:51067121-51067124	oesophagus	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1057T>A; p.Y353N; 18:51065524-51065524	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1529G>T; p.G510V; 18:51078337-51078337	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1529G>T; p.G510V; 18:51078337-51078337	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1072G>T; p.G358*; 18:51065539-51065539	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1072G>T; p.G358*; 18:51065539-51065539	pancreas	other; chronic_pancreatitis	Substitution - Nonsense
c.993G>A; p.M331I; 18:51065460-51065460	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1072G>T; p.G358*; 18:51065539-51065539	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1072G>T; p.G358*; 18:51065539-51065539	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.123A>G; p.E41E; 18:51047169-51047169	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.90A>G; p.G30G; 18:51047136-51047136	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1248A>C; p.R416S; 18:51067127-51067127	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.284A>C; p.Y95S; 18:51048720-51048720	pancreas	NS	Substitution - Missense
c.1472G>T; p.G491V; 18:51078280-51078280	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1283A>T; p.K428M; 18:51067162-51067162	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1504A>G; p.R502G; 18:51078312-51078312	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.971G>A; p.C324Y; 18:51065438-51065438	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.971G>A; p.C324Y; 18:51065438-51065438	thyroid	carcinoma; papillary_carcinoma	Substitution - Missense
c.1505G>A; p.R502K; 18:51078313-51078313	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1504A>G; p.R502G; 18:51078312-51078312	biliary_tract; bile_duct	carcinoma	Substitution - Missense
c.1394_1395insT; p.A466fs*28; 18:51076723-51076724	testis	germ_cell_tumour; seminoma	Insertion - Frameshift
c.1394_1395insT; p.A466fs*28; 18:51076723-51076724	testis	germ_cell_tumour; seminoma	Insertion - Frameshift
c.1539C>G; p.Y513*; 18:51078347-51078347	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.140T>A; p.L47Q; 18:51047186-51047186	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.585delC; p.Y195fs*1; 18:51054911-51054911	pancreas	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.1157G>A; p.G386D; 18:51067036-51067036	pancreas	carcinoma	Substitution - Missense
c.1157G>A; p.G386D; 18:51067036-51067036	small_intestine; duodenum	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>A; p.G386D; 18:51067036-51067036	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.1558G>T; p.E520*; 18:51078366-51078366	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1054G>A; p.G352R; 18:51065521-51065521	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1067_1068CT>AGAAG; p.P356>QK; 18:51065534-51065535	large_intestine	carcinoma; adenocarcinoma	Complex - insertion inframe
c.1157G>A; p.G386D; 18:51067036-51067036	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>A; p.G386D; 18:51067036-51067036	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.1194G>A; p.W398*; 18:51067073-51067073	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1157G>A; p.G386D; 18:51067036-51067036	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.1157G>A; p.G386D; 18:51067036-51067036	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>A; p.G386D; 18:51067036-51067036	pancreas	carcinoma	Substitution - Missense
c.1157G>A; p.G386D; 18:51067036-51067036	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1054G>A; p.G352R; 18:51065521-51065521	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>A; p.G386D; 18:51067036-51067036	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>A; p.G386D; 18:51067036-51067036	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>A; p.G386D; 18:51067036-51067036	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.395A>T; p.H132L; 18:51048831-51048831	small_intestine; ileum	carcinoma; adenocarcinoma	Substitution - Missense
c.1065C>A; p.D355E; 18:51065532-51065532	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.676G>A; p.A226T; 18:51058133-51058133	thyroid	carcinoma; papillary_carcinoma	Substitution - Missense
c.655G>T; p.V219L; 18:51054981-51054981	ovary	other; neoplasm	Substitution - Missense
c.1234T>C; p.Y412H; 18:51067113-51067113	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1450C>T; p.L484L; 18:51078258-51078258	pancreas	carcinoma	Substitution - coding silent
c.1139+3A>T; p.?; 18:51065609-51065609	pancreas	carcinoma	Unknown
c.988G>T; p.E330*; 18:51065455-51065455	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1595C>A; p.A532D; 18:51078403-51078403	pancreas	carcinoma	Substitution - Missense
c.1288T>G; p.Y430D; 18:51067167-51067167	pancreas	carcinoma	Substitution - Missense
c.1658G>T; p.*553?; 18:51078466-51078466	large_intestine	carcinoma; adenocarcinoma	Nonstop extension
c.1658G>T; p.*553?; 18:51078466-51078466	large_intestine; colon	carcinoma; adenocarcinoma	Nonstop extension
c.1595C>A; p.A532D; 18:51078403-51078403	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1349_1376del28; p.Q450fs*17; 18:51076678-51076705	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.407T>C; p.V136A; 18:51048843-51048843	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1309-1G>A; p.?; 18:51076637-51076637	pancreas	carcinoma	Unknown
c.1598T>C; p.L533P; 18:51078406-51078406	pancreas	carcinoma	Substitution - Missense
c.980C>T; p.A327V; 18:51065447-51065447	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.153_154insA; p.K51fs*2; 18:51047199-51047200	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1087T>A; p.C363S; 18:51065554-51065554	small_intestine; jejunum	carcinoma; adenocarcinoma	Substitution - Missense
c.394C>T; p.H132Y; 18:51048830-51048830	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.968G>A; p.W323*; 18:51065435-51065435	pancreas	carcinoma	Substitution - Nonsense
c.153_154insA; p.K51fs*2; 18:51047199-51047200	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.153_154insA; p.K51fs*2; 18:51047199-51047200	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.394C>T; p.H132Y; 18:51048830-51048830	breast	carcinoma	Substitution - Missense
c.1087T>A; p.C363S; 18:51065554-51065554	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.872A>C; p.H291P; 18:51058424-51058424	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.872A>C; p.H291P; 18:51058424-51058424	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1321C>T; p.R441C; 18:51076650-51076650	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.481G>A; p.E161K; 18:51054807-51054807	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1475T>C; p.V492A; 18:51078283-51078283	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1512T>A; p.S504R; 18:51078320-51078320	ovary	carcinoma	Substitution - Missense
c.1614A>G; p.E538E; 18:51078422-51078422	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1392C>T; p.A464A; 18:51076721-51076721	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1512T>A; p.S504R; 18:51078320-51078320	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1321C>T; p.R441C; 18:51076650-51076650	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1321C>T; p.R441C; 18:51076650-51076650	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.757_758delTT; p.F253fs*10; 18:51058214-51058215	stomach	adenocarcinoma	Deletion - Frameshift
c.1512T>A; p.S504R; 18:51078320-51078320	pancreas	carcinoma	Substitution - Missense
c.1321C>T; p.R441C; 18:51076650-51076650	large_intestine; rectum	NS	Substitution - Missense
c.1321C>T; p.R441C; 18:51076650-51076650	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.806_807insT; p.G270fs*3; 18:51058358-51058359	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.931C>T; p.Q311*; 18:51059892-51059892	large_intestine; colon	carcinoma	Substitution - Nonsense
c.608C>T; p.P203L; 18:51054934-51054934	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.931C>T; p.Q311*; 18:51059892-51059892	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.931C>T; p.Q311*; 18:51059892-51059892	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1138A>T; p.R380W; 18:51065605-51065605	pancreas	carcinoma	Substitution - Missense
c.931C>T; p.Q311*; 18:51059892-51059892	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.931C>T; p.Q311*; 18:51059892-51059892	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.608C>T; p.P203L; 18:51054934-51054934	thyroid	adenoma-nodule-goitre	Substitution - Missense
c.931C>T; p.Q311*; 18:51059892-51059892	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1409C>A; p.P470H; 18:51076738-51076738	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.590C>T; p.T197I; 18:51054916-51054916	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.931C>T; p.Q311*; 18:51059892-51059892	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1484T>C; p.L495P; 18:51078292-51078292	ovary	carcinoma	Substitution - Missense
c.737C>T; p.P246L; 18:51058194-51058194	pancreas	other; dysplasia-in_situ_neoplasm	Substitution - Missense
c.1341_1365del25; p.Q448fs*20; 18:51076670-51076694	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1341_1365del25; p.Q448fs*20; 18:51076670-51076694	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.353C>T; p.A118V; 18:51048789-51048789	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.353C>T; p.A118V; 18:51048789-51048789	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.353C>T; p.A118V; 18:51048789-51048789	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1576G>T; p.E526*; 18:51078384-51078384	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.966T>A; p.Y322*; 18:51065433-51065433	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1576G>T; p.E526*; 18:51078384-51078384	breast	carcinoma	Substitution - Nonsense
c.353C>T; p.A118V; 18:51048789-51048789	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.353C>T; p.A118V; 18:51048789-51048789	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.353C>T; p.A118V; 18:51048789-51048789	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.966T>A; p.Y322*; 18:51065433-51065433	pancreas	carcinoma	Substitution - Nonsense
c.1369G>A; p.A457T; 18:51076698-51076698	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1576G>T; p.E526*; 18:51078384-51078384	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.353C>T; p.A118V; 18:51048789-51048789	pancreas	carcinoma	Substitution - Missense
c.906G>A; p.W302*; 18:51059867-51059867	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1576G>T; p.E526*; 18:51078384-51078384	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.353C>T; p.A118V; 18:51048789-51048789	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.906G>A; p.W302*; 18:51059867-51059867	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.353C>T; p.A118V; 18:51048789-51048789	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1256G>T; p.G419V; 18:51067135-51067135	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.996T>A; p.D332E; 18:51065463-51065463	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.611C>A; p.S204Y; 18:51054937-51054937	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256G>T; p.G419V; 18:51067135-51067135	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1598T>G; p.L533R; 18:51078406-51078406	large_intestine; colon	NS	Substitution - Missense
c.1598T>G; p.L533R; 18:51078406-51078406	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1053T>C; p.D351D; 18:51065520-51065520	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1293delA; p.S432fs*4; 18:51067172-51067172	pancreas	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.88G>T; p.G30*; 18:51047134-51047134	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1064A>T; p.D355V; 18:51065531-51065531	pancreas	carcinoma	Substitution - Missense
c.1064A>T; p.D355V; 18:51065531-51065531	pancreas	carcinoma	Substitution - Missense
c.397T>A; p.Y133N; 18:51048833-51048833	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1029A>G; p.S343S; 18:51065496-51065496	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1565C>T; p.P522L; 18:51078373-51078373	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1657T>G; p.*553G; 18:51078465-51078465	pancreas	carcinoma	Nonstop extension
c.1526G>A; p.W509*; 18:51078334-51078334	prostate	carcinoma	Substitution - Nonsense
c.1216G>A; p.A406T; 18:51067095-51067095	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1216G>A; p.A406T; 18:51067095-51067095	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1081C>G; p.R361G; 18:51065548-51065548	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1216G>A; p.A406T; 18:51067095-51067095	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.298A>G; p.R100G; 18:51048734-51048734	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.298A>G; p.R100G; 18:51048734-51048734	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.298A>G; p.R100G; 18:51048734-51048734	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>G; p.R361G; 18:51065548-51065548	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1216G>A; p.A406T; 18:51067095-51067095	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>G; p.R361G; 18:51065548-51065548	pancreas	carcinoma	Substitution - Missense
c.1216G>A; p.A406T; 18:51067095-51067095	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.992T>C; p.M331T; 18:51065459-51065459	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.992T>C; p.M331T; 18:51065459-51065459	thyroid	carcinoma; Hurthle_cell_carcinoma	Substitution - Missense
c.257G>T; p.G86V; 18:51048693-51048693	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1598_1599insCAG; p.L533_Q534insS; 18:51078406-51078407	pancreas	carcinoma	Insertion - In frame
c.257G>T; p.G86V; 18:51048693-51048693	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.850C>T; p.Q284*; 18:51058402-51058402	pancreas	carcinoma	Substitution - Nonsense
c.956-2G>A; p.?; 18:51065421-51065421	pancreas	carcinoma; ductal_carcinoma	Unknown
c.951T>A; p.H317Q; 18:51059912-51059912	thyroid	adenoma-nodule-goitre	Substitution - Missense
c.1447+1G>C; p.?; 18:51076777-51076777	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.607_608delCC; p.P203fs*2; 18:51054933-51054934	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.106_135del30; p.A36_K45del10; 18:51047152-51047181	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.1516G>A; p.V506M; 18:51078324-51078324	large_intestine; appendix	carcinoma; adenocarcinoma	Substitution - Missense
c.1229_1230insCA; p.Q410fs*6; 18:51067108-51067109	pancreas	NS	Insertion - Frameshift
c.1229_1230insCA; p.Q410fs*6; 18:51067108-51067109	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.430T>C; p.S144P; 18:51049300-51049300	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.990A>G; p.E330E; 18:51065457-51065457	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1600delC; p.Q534fs*3; 18:51078408-51078408	pancreas	NS	Deletion - Frameshift
c.1283A>G; p.K428R; 18:51067162-51067162	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.1018A>G; p.K340E; 18:51065485-51065485	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1018A>G; p.K340E; 18:51065485-51065485	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1609G>T; p.D537Y; 18:51078417-51078417	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1609G>T; p.D537Y; 18:51078417-51078417	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1612G>A; p.E538K; 18:51078420-51078420	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1612G>A; p.E538K; 18:51078420-51078420	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1093G>C; p.G365R; 18:51065560-51065560	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1609G>T; p.D537Y; 18:51078417-51078417	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1609G>T; p.D537Y; 18:51078417-51078417	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1138A>G; p.R380G; 18:51065605-51065605	pancreas	carcinoma	Substitution - Missense
c.1609G>T; p.D537Y; 18:51078417-51078417	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.573G>A; p.S191S; 18:51054899-51054899	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.573G>A; p.S191S; 18:51054899-51054899	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1509G>T; p.M503I; 18:51078317-51078317	pancreas	carcinoma	Substitution - Missense
c.1066C>T; p.P356S; 18:51065533-51065533	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1066C>T; p.P356S; 18:51065533-51065533	liver	carcinoma	Substitution - Missense
c.956-1G>C; p.?; 18:51065422-51065422	lung	carcinoma; adenocarcinoma	Unknown
c.353C>A; p.A118E; 18:51048789-51048789	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.252G>T; p.V84V; 18:51048688-51048688	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1145A>T; p.H382L; 18:51067024-51067024	pancreas	carcinoma	Substitution - Missense
c.1066C>T; p.P356S; 18:51065533-51065533	liver	carcinoma	Substitution - Missense
c.1546_1553delCAGAGCAT; p.S517fs*7; 18:51078354-51078361	pancreas	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.1546_1553delCAGAGCAT; p.S517fs*7; 18:51078354-51078361	pancreas	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.976A>C; p.I326L; 18:51065443-51065443	liver	carcinoma	Substitution - Missense
c.1066C>T; p.P356S; 18:51065533-51065533	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.426T>C; p.D142D; 18:51049296-51049296	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1064A>C; p.D355A; 18:51065531-51065531	large_intestine; colon	adenoma	Substitution - Missense
c.74G>A; p.C25Y; 18:51047120-51047120	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1591C>T; p.R531W; 18:51078399-51078399	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1591C>T; p.R531W; 18:51078399-51078399	pancreas	carcinoma	Substitution - Missense
c.1591C>T; p.R531W; 18:51078399-51078399	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.74G>A; p.C25Y; 18:51047120-51047120	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.169T>G; p.L57V; 18:51047215-51047215	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	small_intestine; jejunum	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.193G>A; p.G65R; 18:51047239-51047239	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.349T>C; p.Y117H; 18:51048785-51048785	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	pancreas	carcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	pancreas	carcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	pancreas	carcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	small_intestine; jejunum	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	breast	carcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.974_975delCC; p.S325fs*5; 18:51065441-51065442	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1082G>A; p.R361H; 18:51065549-51065549	pancreas	carcinoma	Substitution - Missense
c.1067_1068delCT; p.P356fs*21; 18:51065534-51065535	peritoneum; appendix	other; pseudomyxoma_peritonei	Deletion - Frameshift
c.1283A>C; p.K428T; 18:51067162-51067162	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1607_1607delT; p.L536fs*16; 18:51078415-51078415	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1283A>C; p.K428T; 18:51067162-51067162	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.320_321insA; p.N107fs*2; 18:51048756-51048757	pancreas	NS	Insertion - Frameshift
c.1481A>G; p.D494G; 18:51078289-51078289	pancreas	NS	Substitution - Missense
c.1481A>G; p.D494G; 18:51078289-51078289	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1481A>G; p.D494G; 18:51078289-51078289	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1481A>G; p.D494G; 18:51078289-51078289	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1481A>G; p.D494G; 18:51078289-51078289	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1029A>T; p.S343S; 18:51065496-51065496	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.295T>C; p.W99R; 18:51048731-51048731	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.170T>C; p.L57S; 18:51047216-51047216	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.895G>A; p.G299R; 18:51058447-51058447	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.973_976delTCCA; p.S325fs*10; 18:51065440-51065443	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1015_1029del15; p.F339_S343del; 18:51065482-51065496	large_intestine	carcinoma; adenocarcinoma	Deletion - In frame
c.383T>C; p.V128A; 18:51048819-51048819	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1447_1447+3delAGTA; p.?; 18:51076776-51076779	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Unknown
c.170T>C; p.L57S; 18:51047216-51047216	pancreas	carcinoma	Substitution - Missense
c.1015_1029del15; p.F339_S343del; 18:51065482-51065496	large_intestine	carcinoma; adenocarcinoma	Deletion - In frame
c.828C>A; p.Y276*; 18:51058380-51058380	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.383T>C; p.V128A; 18:51048819-51048819	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1468A>G; p.I490V; 18:51078276-51078276	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1480G>A; p.D494N; 18:51078288-51078288	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1156G>T; p.G386C; 18:51067035-51067035	ovary	carcinoma	Substitution - Missense
c.1511G>T; p.S504I; 18:51078319-51078319	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1369G>T; p.A457S; 18:51076698-51076698	pancreas	carcinoid-endocrine_tumour; non_functioning	Substitution - Missense
c.924T>C; p.L308L; 18:51059885-51059885	thyroid	adenoma-nodule-goitre	Substitution - coding silent
c.924T>C; p.L308L; 18:51059885-51059885	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1490G>A; p.R497H; 18:51078298-51078298	biliary_tract; bile_duct	carcinoma	Substitution - Missense
c.275delA; p.H92fs*2; 18:51048711-51048711	pancreas	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.1490G>A; p.R497H; 18:51078298-51078298	large_intestine	adenoma	Substitution - Missense
c.1476T>C; p.V492V; 18:51078284-51078284	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1148T>G; p.I383R; 18:51067027-51067027	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.984C>T; p.Y328Y; 18:51065451-51065451	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.394C>A; p.H132N; 18:51048830-51048830	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1527G>A; p.W509*; 18:51078335-51078335	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.314_317delACAA; p.H105fs*4; 18:51048750-51048753	pancreas	NS	Deletion - Frameshift
c.1527G>A; p.W509*; 18:51078335-51078335	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.394C>A; p.H132N; 18:51048830-51048830	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.1611C>A; p.D537E; 18:51078419-51078419	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1611C>A; p.D537E; 18:51078419-51078419	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1474G>T; p.V492F; 18:51078282-51078282	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1474G>T; p.V492F; 18:51078282-51078282	biliary_tract; bile_duct	carcinoma	Substitution - Missense
c.1009G>A; p.E337K; 18:51065476-51065476	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1236C>G; p.Y412*; 18:51067115-51067115	pancreas	carcinoma	Substitution - Nonsense
c.968_974delGGTGTTC; p.W323fs*11; 18:51065435-51065441	small_intestine; jejunum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.692_693insG; p.S232fs*3; 18:51058149-51058150	pancreas	NS	Insertion - Frameshift
c.250-2A>G; p.?; 18:51048684-51048684	pancreas	carcinoma; ductal_carcinoma	Unknown
c.250-2A>G; p.?; 18:51048684-51048684	pancreas	carcinoma	Unknown
c.1236C>G; p.Y412*; 18:51067115-51067115	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1236C>G; p.Y412*; 18:51067115-51067115	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1255G>A; p.G419R; 18:51067134-51067134	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1249G>T; p.E417*; 18:51067128-51067128	pancreas	carcinoma	Substitution - Nonsense
c.1249G>T; p.E417*; 18:51067128-51067128	pancreas	carcinoma	Substitution - Nonsense
c.1156G>A; p.G386S; 18:51067035-51067035	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.991A>G; p.M331V; 18:51065458-51065458	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1249G>T; p.E417*; 18:51067128-51067128	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1156G>A; p.G386S; 18:51067035-51067035	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.502G>T; p.G168*; 18:51054828-51054828	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1001A>G; p.Q334R; 18:51065468-51065468	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.502G>T; p.G168*; 18:51054828-51054828	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1001A>G; p.Q334R; 18:51065468-51065468	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1355_1356insT; p.T453fs*41; 18:51076684-51076685	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.1630C>T; p.P544S; 18:51078438-51078438	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.461C>G; p.S154*; 18:51054787-51054787	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1001A>G; p.Q334R; 18:51065468-51065468	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1576G>A; p.E526K; 18:51078384-51078384	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.502G>T; p.G168*; 18:51054828-51054828	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1576G>A; p.E526K; 18:51078384-51078384	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.994G>T; p.D332Y; 18:51065461-51065461	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1001A>G; p.Q334R; 18:51065468-51065468	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1548_1555delGAGCATCA; p.S517fs*7; 18:51078356-51078363	pancreas	NS	Deletion - Frameshift
c.1241_1242insAA; p.D415fs*22; 18:51067120-51067121	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.1519A>C; p.K507Q; 18:51078327-51078327	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1519A>C; p.K507Q; 18:51078327-51078327	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.157G>T; p.E53*; 18:51047203-51047203	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1055G>C; p.G352A; 18:51065522-51065522	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1521A>G; p.K507K; 18:51078329-51078329	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1521A>G; p.K507K; 18:51078329-51078329	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.941T>A; p.I314N; 18:51059902-51059902	thyroid	adenoma-nodule-goitre; Hurthle_cell_adenoma	Substitution - Missense
c.1378G>T; p.A460S; 18:51076707-51076707	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.153A>G; p.K51K; 18:51047199-51047199	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1521A>G; p.K507K; 18:51078329-51078329	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.370G>T; p.D124Y; 18:51048806-51048806	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1255G>T; p.G419W; 18:51067134-51067134	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.686_687insG; p.S232fs*3; 18:51058143-51058144	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.363_364insA; p.C123fs*2; 18:51048799-51048800	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.686_687insG; p.S232fs*3; 18:51058143-51058144	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.153A>G; p.K51K; 18:51047199-51047199	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.363_364insA; p.C123fs*2; 18:51048799-51048800	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.153A>G; p.K51K; 18:51047199-51047199	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.208A>T; p.K70*; 18:51047254-51047254	pancreas	carcinoma	Substitution - Nonsense
c.1447+5G>A; p.?; 18:51076781-51076781	large_intestine	carcinoma; adenocarcinoma	Unknown
c.1001A>T; p.Q334L; 18:51065468-51065468	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1517T>C; p.V506A; 18:51078325-51078325	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1334G>A; p.R445Q; 18:51076663-51076663	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.978delT; p.I326fs*10; 18:51065445-51065445	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.970T>C; p.C324R; 18:51065437-51065437	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.431C>A; p.S144*; 18:51049301-51049301	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.733C>T; p.Q245*; 18:51058190-51058190	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.733C>T; p.Q245*; 18:51058190-51058190	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.733C>T; p.Q245*; 18:51058190-51058190	breast	carcinoma	Substitution - Nonsense
c.194G>A; p.G65E; 18:51047240-51047240	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1284G>C; p.K428N; 18:51067163-51067163	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.733C>T; p.Q245*; 18:51058190-51058190	upper_aerodigestive_tract; head_neck	carcinoma	Substitution - Nonsense
c.733C>T; p.Q245*; 18:51058190-51058190	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.115G>A; p.A39T; 18:51047161-51047161	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1051G>A; p.D351N; 18:51065518-51065518	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.733C>T; p.Q245*; 18:51058190-51058190	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.733C>T; p.Q245*; 18:51058190-51058190	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.115G>A; p.A39T; 18:51047161-51047161	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.733C>T; p.Q245*; 18:51058190-51058190	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1051G>T; p.D351Y; 18:51065518-51065518	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.43G>A; p.A15T; 18:51047089-51047089	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.966T>G; p.Y322*; 18:51065433-51065433	pancreas	carcinoma	Substitution - Nonsense
c.1051G>T; p.D351Y; 18:51065518-51065518	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.643C>T; p.P215S; 18:51054969-51054969	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1473T>G; p.G491G; 18:51078281-51078281	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1351_1375del25; p.A451fs*17; 18:51076680-51076704	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.344G>A; p.C115Y; 18:51048780-51048780	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1322G>C; p.R441P; 18:51076651-51076651	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.776_777delCT; p.T259fs*4; 18:51058233-51058234	pancreas	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.405A>G; p.R135R; 18:51048841-51048841	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.523G>C; p.E175Q; 18:51054849-51054849	pancreas	carcinoma	Substitution - Missense
c.776_777delCT; p.T259fs*4; 18:51058233-51058234	pancreas	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.424+1G>A; p.?; 18:51048861-51048861	pancreas	carcinoma	Unknown
c.405A>G; p.R135R; 18:51048841-51048841	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1051G>C; p.D351H; 18:51065518-51065518	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1051G>C; p.D351H; 18:51065518-51065518	ovary	carcinoma	Substitution - Missense
c.1051G>C; p.D351H; 18:51065518-51065518	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.425-26T>C; p.?; 18:51049269-51049269	thyroid	other; hyperplasia	Unknown
c.737C>G; p.P246R; 18:51058194-51058194	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.128T>C; p.L43S; 18:51047174-51047174	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1051G>C; p.D351H; 18:51065518-51065518	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1011G>A; p.E337E; 18:51065478-51065478	pancreas	other; dysplasia-in_situ_neoplasm	Substitution - coding silent
c.1051G>C; p.D351H; 18:51065518-51065518	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1051G>C; p.D351H; 18:51065518-51065518	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1051G>C; p.D351H; 18:51065518-51065518	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1051G>C; p.D351H; 18:51065518-51065518	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1051G>C; p.D351H; 18:51065518-51065518	pancreas	carcinoma	Substitution - Missense
c.128T>C; p.L43S; 18:51047174-51047174	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1051G>C; p.D351H; 18:51065518-51065518	ovary	carcinoma	Substitution - Missense
c.1051G>C; p.D351H; 18:51065518-51065518	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1051G>C; p.D351H; 18:51065518-51065518	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1222T>C; p.F408L; 18:51067101-51067101	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1051G>C; p.D351H; 18:51065518-51065518	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1607T>A; p.L536Q; 18:51078415-51078415	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1529G>A; p.G510E; 18:51078337-51078337	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.343T>C; p.C115R; 18:51048779-51048779	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1607T>A; p.L536Q; 18:51078415-51078415	pancreas	carcinoma	Substitution - Missense
c.1529G>A; p.G510E; 18:51078337-51078337	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1590C>T; p.H530H; 18:51078398-51078398	skin	malignant_melanoma	Substitution - coding silent
c.1063G>T; p.D355Y; 18:51065530-51065530	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.21G>A; p.T7T; 18:51047067-51047067	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.170T>A; p.L57*; 18:51047216-51047216	gastrointestinal_tract_(site_indeterminate)	other; juvenile_polyp	Substitution - Nonsense
c.1320_1377del58; p.R441fs*16; 18:51076649-51076706	pancreas	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.116C>G; p.A39G; 18:51047162-51047162	pancreas	carcinoma	Substitution - Missense
c.956-1G>A; p.?; 18:51065422-51065422	pancreas	NS	Unknown
c.1610A>T; p.D537V; 18:51078418-51078418	pancreas	carcinoma	Substitution - Missense
c.1147A>G; p.I383V; 18:51067026-51067026	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1610A>T; p.D537V; 18:51078418-51078418	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.687delG; p.G231fs*10; 18:51058144-51058144	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1063G>A; p.D355N; 18:51065530-51065530	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.1610A>T; p.D537V; 18:51078418-51078418	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.1069T>C; p.S357P; 18:51065536-51065536	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.514T>A; p.L172M; 18:51054840-51054840	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1027T>C; p.S343P; 18:51065494-51065494	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.780C>A; p.Y260*; 18:51058237-51058237	pancreas	carcinoma	Substitution - Nonsense
c.377T>C; p.V126A; 18:51048813-51048813	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.377T>C; p.V126A; 18:51048813-51048813	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1144C>G; p.H382D; 18:51067023-51067023	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1557A>C; p.K519N; 18:51078365-51078365	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1027T>C; p.S343P; 18:51065494-51065494	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1657T>C; p.*553R; 18:51078465-51078465	pancreas	carcinoma	Nonstop extension
c.1002G>T; p.Q334H; 18:51065469-51065469	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.271C>T; p.P91S; 18:51048707-51048707	skin	malignant_melanoma	Substitution - Missense
c.955+5G>C; p.?; 18:51059921-51059921	large_intestine	carcinoma; adenocarcinoma	Unknown
c.1052A>T; p.D351V; 18:51065519-51065519	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.955+5G>C; p.?; 18:51059921-51059921	large_intestine	carcinoma; adenocarcinoma	Unknown
c.955+5G>C; p.?; 18:51059921-51059921	large_intestine	carcinoma; adenocarcinoma	Unknown
c.950A>G; p.H317R; 18:51059911-51059911	ovary	low_malignant_potential_(borderline)_tumour; mucinous	Substitution - Missense
c.1454C>A; p.S485*; 18:51078262-51078262	pancreas	carcinoma	Substitution - Nonsense
c.161T>C; p.L54S; 18:51047207-51047207	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1068T>C; p.P356P; 18:51065535-51065535	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1544G>C; p.R515T; 18:51078352-51078352	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1597C>T; p.L533F; 18:51078405-51078405	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.431C>T; p.S144L; 18:51049301-51049301	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.431C>T; p.S144L; 18:51049301-51049301	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.431C>T; p.S144L; 18:51049301-51049301	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.431C>T; p.S144L; 18:51049301-51049301	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1595C>T; p.A532V; 18:51078403-51078403	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1224T>A; p.F408L; 18:51067103-51067103	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.296G>A; p.W99*; 18:51048732-51048732	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.788A>G; p.N263S; 18:51058340-51058340	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.298A>T; p.R100W; 18:51048734-51048734	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.788A>G; p.N263S; 18:51058340-51058340	thyroid	carcinoma; papillary_carcinoma	Substitution - Missense
c.383_384insA; p.N129fs*14; 18:51048819-51048820	pancreas	carcinoma	Insertion - Frameshift
c.683_684insT; p.L229fs*6; 18:51058140-51058141	pancreas	other; pancreatoblastoma	Insertion - Frameshift
c.1049_1051TTG>ATA; p.V350_D351>DN; 18:51065516-51065518	small_intestine; jejunum	carcinoma; adenocarcinoma	Complex - compound substitution
c.296G>A; p.W99*; 18:51048732-51048732	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1087T>C; p.C363R; 18:51065554-51065554	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.298A>T; p.R100W; 18:51048734-51048734	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1519A>G; p.K507E; 18:51078327-51078327	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1577A>T; p.E526V; 18:51078385-51078385	pancreas	carcinoma	Substitution - Missense
c.1519A>G; p.K507E; 18:51078327-51078327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1519A>G; p.K507E; 18:51078327-51078327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1519A>G; p.K507E; 18:51078327-51078327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1577A>T; p.E526V; 18:51078385-51078385	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.209A>C; p.K70T; 18:51047255-51047255	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1519A>G; p.K507E; 18:51078327-51078327	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1519A>G; p.K507E; 18:51078327-51078327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1028_1029insTC; p.S344fs*41; 18:51065495-51065496	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.1543A>T; p.R515*; 18:51078351-51078351	pancreas	carcinoid-endocrine_tumour; non_functioning	Substitution - Nonsense
c.89_90delGA; p.S32fs*1; 18:51047135-51047136	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.907_908insC; p.V304fs*4; 18:51059868-51059869	thyroid	carcinoma; papillary_carcinoma	Insertion - Frameshift
c.1543A>T; p.R515*; 18:51078351-51078351	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.389C>T; p.P130L; 18:51048825-51048825	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.89_90delGA; p.S32fs*1; 18:51047135-51047136	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Deletion - Frameshift
c.389C>T; p.P130L; 18:51048825-51048825	pancreas	carcinoma	Substitution - Missense
c.389C>T; p.P130L; 18:51048825-51048825	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.454+2T>A; p.?; 18:51049326-51049326	pancreas	carcinoma	Unknown
c.1543A>T; p.R515*; 18:51078351-51078351	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1088G>A; p.C363Y; 18:51065555-51065555	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.135G>T; p.K45N; 18:51047181-51047181	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1088G>A; p.C363Y; 18:51065555-51065555	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.400G>A; p.E134K; 18:51048836-51048836	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1088G>A; p.C363Y; 18:51065555-51065555	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1480G>T; p.D494Y; 18:51078288-51078288	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1088G>A; p.C363Y; 18:51065555-51065555	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1480G>T; p.D494Y; 18:51078288-51078288	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1480G>T; p.D494Y; 18:51078288-51078288	urinary_tract; bladder	carcinoma	Substitution - Missense
c.904T>C; p.W302R; 18:51058456-51058456	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.400G>A; p.E134K; 18:51048836-51048836	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1477G>A; p.D493N; 18:51078285-51078285	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.1000C>T; p.Q334*; 18:51065467-51065467	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Nonsense
c.1477G>A; p.D493N; 18:51078285-51078285	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1010A>G; p.E337G; 18:51065477-51065477	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1477G>A; p.D493N; 18:51078285-51078285	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.678C>T; p.A226A; 18:51058135-51058135	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.129G>T; p.L43F; 18:51047175-51047175	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1010A>G; p.E337G; 18:51065477-51065477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1010A>G; p.E337G; 18:51065477-51065477	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1226_1239del14; p.Q410fs*14; 18:51067105-51067118	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1010A>G; p.E337G; 18:51065477-51065477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>A; p.R361S; 18:51065548-51065548	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>A; p.R361S; 18:51065548-51065548	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1477G>A; p.D493N; 18:51078285-51078285	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.1010A>G; p.E337G; 18:51065477-51065477	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.129G>T; p.L43F; 18:51047175-51047175	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1010A>G; p.E337G; 18:51065477-51065477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.491A>G; p.H164R; 18:51054817-51054817	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.533C>A; p.S178*; 18:51054859-51054859	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1028C>A; p.S343*; 18:51065495-51065495	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1607_1626del20; p.L536fs*11; 18:51078415-51078434	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1096C>T; p.Q366*; 18:51065563-51065563	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1517T>A; p.V506E; 18:51078325-51078325	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1096C>T; p.Q366*; 18:51065563-51065563	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.533C>A; p.S178*; 18:51054859-51054859	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1096C>T; p.Q366*; 18:51065563-51065563	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1616T>G; p.V539G; 18:51078424-51078424	pancreas	other; chronic_pancreatitis	Substitution - Missense
c.988G>A; p.E330K; 18:51065455-51065455	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.988G>A; p.E330K; 18:51065455-51065455	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.988G>A; p.E330K; 18:51065455-51065455	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.1484T>G; p.L495R; 18:51078292-51078292	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.227G>T; p.R76I; 18:51047273-51047273	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.988G>A; p.E330K; 18:51065455-51065455	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.988G>A; p.E330K; 18:51065455-51065455	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.988G>A; p.E330K; 18:51065455-51065455	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.318_319insA; p.N107fs*2; 18:51048754-51048755	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.1319T>A; p.L440*; 18:51076648-51076648	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1545A>G; p.R515R; 18:51078353-51078353	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1148T>A; p.I383K; 18:51067027-51067027	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1545A>G; p.R515R; 18:51078353-51078353	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1545A>G; p.R515R; 18:51078353-51078353	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1545A>G; p.R515R; 18:51078353-51078353	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1591C>A; p.R531R; 18:51078399-51078399	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1591C>A; p.R531R; 18:51078399-51078399	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1591C>A; p.R531R; 18:51078399-51078399	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1591C>A; p.R531R; 18:51078399-51078399	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1591C>A; p.R531R; 18:51078399-51078399	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.395A>G; p.H132R; 18:51048831-51048831	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.395A>G; p.H132R; 18:51048831-51048831	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1006G>A; p.G336R; 18:51065473-51065473	pancreas	carcinoma	Substitution - Missense
c.535A>T; p.I179F; 18:51054861-51054861	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.290G>A; p.R97H; 18:51048726-51048726	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1271A>T; p.D424V; 18:51067150-51067150	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.930C>G; p.F310L; 18:51059891-51059891	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.290G>A; p.R97H; 18:51048726-51048726	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1540C>T; p.P514S; 18:51078348-51078348	skin	malignant_melanoma	Substitution - Missense
c.1659+12G>A; p.?; 18:51078479-51078479	oesophagus	carcinoma; squamous_cell_carcinoma	Unknown
c.1140-2A>T; p.?; 18:51067017-51067017	pancreas	carcinoma	Unknown
c.290G>A; p.R97H; 18:51048726-51048726	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1123_1134del12; p.A375_R378del; 18:51065590-51065601	large_intestine	carcinoma; adenocarcinoma	Deletion - In frame
c.1523G>A; p.G508D; 18:51078331-51078331	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1523G>A; p.G508D; 18:51078331-51078331	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.725C>G; p.S242*; 18:51058182-51058182	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Nonsense
c.1308G>T; p.K436N; 18:51067187-51067187	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.725C>G; p.S242*; 18:51058182-51058182	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1446_1447insAATA; p.I482fs*12; 18:51076775-51076776	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - Frameshift
c.121G>A; p.E41K; 18:51047167-51047167	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1298C>T; p.A433V; 18:51067177-51067177	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1473T>C; p.G491G; 18:51078281-51078281	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1659+26C>A; p.?; 18:51078493-51078493	thyroid	adenoma-nodule-goitre	Unknown
c.1473T>C; p.G491G; 18:51078281-51078281	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1067C>G; p.P356R; 18:51065534-51065534	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1067C>G; p.P356R; 18:51065534-51065534	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1528G>A; p.G510R; 18:51078336-51078336	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1478A>C; p.D493A; 18:51078286-51078286	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1067C>G; p.P356R; 18:51065534-51065534	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1478A>C; p.D493A; 18:51078286-51078286	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1086_1088delTTG; p.C363delC; 18:51065553-51065555	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - In frame
c.1134_1135delAG; p.R378fs*14; 18:51065601-51065602	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.127T>C; p.L43L; 18:51047173-51047173	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1370C>T; p.A457V; 18:51076699-51076699	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.821C>A; p.A274E; 18:51058373-51058373	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.305C>A; p.P102H; 18:51048741-51048741	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.299G>C; p.R100T; 18:51048735-51048735	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.326T>G; p.L109R; 18:51048762-51048762	breast	carcinoma	Substitution - Missense
c.178G>C; p.A60P; 18:51047224-51047224	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.299G>C; p.R100T; 18:51048735-51048735	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1052_1054delATG; p.D351del; 18:51065519-51065521	large_intestine	carcinoma; adenocarcinoma	Deletion - In frame
c.1572G>T; p.W524C; 18:51078380-51078380	pancreas	carcinoma	Substitution - Missense
c.299G>C; p.R100T; 18:51048735-51048735	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1572G>T; p.W524C; 18:51078380-51078380	pancreas	carcinoma	Substitution - Missense
c.1572G>T; p.W524C; 18:51078380-51078380	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.788-1G>T; p.?; 18:51058339-51058339	pancreas	carcinoma; ductal_carcinoma	Unknown
c.1333C>T; p.R445*; 18:51076662-51076662	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma	Substitution - Nonsense
c.1103C>G; p.S368C; 18:51065570-51065570	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.125G>T; p.S42I; 18:51047171-51047171	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	small_intestine; duodenum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1659A>G; p.*553W; 18:51078467-51078467	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Nonstop extension
c.1333C>T; p.R445*; 18:51076662-51076662	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.392A>G; p.Y131C; 18:51048828-51048828	pancreas	carcinoma	Substitution - Missense
c.654T>C; p.P218P; 18:51054980-51054980	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1223T>C; p.F408S; 18:51067102-51067102	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.788-1G>T; p.?; 18:51058339-51058339	lung	carcinoma; adenocarcinoma	Unknown
c.392A>G; p.Y131C; 18:51048828-51048828	pancreas	NS	Substitution - Missense
c.1333C>T; p.R445*; 18:51076662-51076662	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma	Substitution - Nonsense
c.1621C>T; p.H541Y; 18:51078429-51078429	prostate	carcinoma	Substitution - Missense
c.1333C>T; p.R445*; 18:51076662-51076662	pancreas	carcinoma	Substitution - Nonsense
c.1333C>T; p.R445*; 18:51076662-51076662	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1028C>G; p.S343*; 18:51065495-51065495	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1028C>G; p.S343*; 18:51065495-51065495	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.778_779insT; p.Y260fs*4; 18:51058235-51058236	pancreas	NS	Insertion - Frameshift
c.778_779insT; p.Y260fs*4; 18:51058235-51058236	pancreas	carcinoma	Insertion - Frameshift
c.1074A>G; p.G358G; 18:51065541-51065541	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1028C>G; p.S343*; 18:51065495-51065495	pancreas	carcinoma; adenocarcinoma	Substitution - Nonsense
c.512C>A; p.S171*; 18:51054838-51054838	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1028C>G; p.S343*; 18:51065495-51065495	biliary_tract; bile_duct	carcinoma	Substitution - Nonsense
c.1597C>G; p.L533V; 18:51078405-51078405	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1611C>G; p.D537E; 18:51078419-51078419	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.785A>G; p.H262R; 18:51058242-51058242	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.766C>T; p.Q256*; 18:51058223-51058223	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1105A>G; p.N369D; 18:51065572-51065572	pancreas	carcinoid-endocrine_tumour; non_functioning	Substitution - Missense
c.766C>T; p.Q256*; 18:51058223-51058223	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.715C>T; p.Q239*; 18:51058172-51058172	liver	carcinoma	Substitution - Nonsense
c.1608_1613delAGACGA; p.D537_E538delDE; 18:51078416-51078421	pancreas	carcinoma	Deletion - In frame
c.1632G>T; p.P544P; 18:51078440-51078440	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.715C>T; p.Q239*; 18:51058172-51058172	liver	carcinoma	Substitution - Nonsense
c.715C>T; p.Q239*; 18:51058172-51058172	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.715C>T; p.Q239*; 18:51058172-51058172	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.928T>C; p.F310L; 18:51059889-51059889	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1577A>C; p.E526A; 18:51078385-51078385	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.390A>G; p.P130P; 18:51048826-51048826	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1571G>C; p.W524S; 18:51078379-51078379	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.385A>G; p.N129D; 18:51048821-51048821	pancreas	carcinoma	Substitution - Missense
c.1094G>A; p.G365D; 18:51065561-51065561	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.484_485delTA; p.Y162fs*3; 18:51054810-51054811	pancreas	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.984C>A; p.Y328*; 18:51065451-51065451	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1201T>C; p.C401R; 18:51067080-51067080	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1255G>C; p.G419R; 18:51067134-51067134	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1520A>G; p.K507R; 18:51078328-51078328	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1520A>G; p.K507R; 18:51078328-51078328	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>C; p.G386A; 18:51067036-51067036	pancreas	carcinoma	Substitution - Missense
c.865C>T; p.Q289*; 18:51058417-51058417	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.220_221insT; p.Q75fs*29; 18:51047266-51047267	liver	carcinoma	Insertion - Frameshift
c.97G>T; p.E33*; 18:51047143-51047143	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.865C>T; p.Q289*; 18:51058417-51058417	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.97G>T; p.E33*; 18:51047143-51047143	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.884C>T; p.P295L; 18:51058436-51058436	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.944delC; p.N316fs*20; 18:51059905-51059905	breast	carcinoma	Deletion - Frameshift
c.388C>T; p.P130S; 18:51048824-51048824	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1414C>A; p.P472T; 18:51076743-51076743	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1354G>A; p.A452T; 18:51076683-51076683	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1601A>C; p.Q534P; 18:51078409-51078409	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1134A>G; p.R378R; 18:51065601-51065601	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.403C>T; p.R135*; 18:51048839-51048839	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.403C>T; p.R135*; 18:51048839-51048839	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.403C>T; p.R135*; 18:51048839-51048839	gastrointestinal_tract_(site_indeterminate)	other; juvenile_polyp	Substitution - Nonsense
c.403C>T; p.R135*; 18:51048839-51048839	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.403C>T; p.R135*; 18:51048839-51048839	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.403C>T; p.R135*; 18:51048839-51048839	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.403C>T; p.R135*; 18:51048839-51048839	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1477G>T; p.D493Y; 18:51078285-51078285	pancreas	other; pancreatoblastoma	Substitution - Missense
c.403C>T; p.R135*; 18:51048839-51048839	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.988G>C; p.E330Q; 18:51065455-51065455	large_intestine; colon	adenoma	Substitution - Missense
c.403C>T; p.R135*; 18:51048839-51048839	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.403C>T; p.R135*; 18:51048839-51048839	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.988G>C; p.E330Q; 18:51065455-51065455	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1335A>G; p.R445R; 18:51076664-51076664	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1335A>G; p.R445R; 18:51076664-51076664	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.403C>T; p.R135*; 18:51048839-51048839	pancreas	carcinoma	Substitution - Nonsense
c.116C>A; p.A39E; 18:51047162-51047162	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.904+2T>C; p.?; 18:51058458-51058458	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1607_1612delTAGACG; p.L536_E538>Q; 18:51078415-51078420	oesophagus	carcinoma; adenocarcinoma	Complex - deletion inframe
c.116C>A; p.A39E; 18:51047162-51047162	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.379T>A; p.C127S; 18:51048815-51048815	pancreas	carcinoma	Substitution - Missense
c.1543A>G; p.R515G; 18:51078351-51078351	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1569C>G; p.C523W; 18:51078377-51078377	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1569C>G; p.C523W; 18:51078377-51078377	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1577A>G; p.E526G; 18:51078385-51078385	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1583_1586delACTT; p.L529fs*7; 18:51078391-51078394	pancreas	carcinoid-endocrine_tumour; non_functioning	Deletion - Frameshift
c.1569C>G; p.C523W; 18:51078377-51078377	biliary_tract; bile_duct	carcinoma	Substitution - Missense
c.951T>C; p.H317H; 18:51059912-51059912	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1612G>T; p.E538*; 18:51078420-51078420	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1612G>T; p.E538*; 18:51078420-51078420	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1599C>T; p.L533L; 18:51078407-51078407	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1612G>T; p.E538*; 18:51078420-51078420	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.387T>G; p.N129K; 18:51048823-51048823	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1612G>T; p.E538*; 18:51078420-51078420	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1308+2T>G; p.?; 18:51067189-51067189	large_intestine	carcinoma; adenocarcinoma	Unknown
c.131T>G; p.V44G; 18:51047177-51047177	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1052A>G; p.D351G; 18:51065519-51065519	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1052A>G; p.D351G; 18:51065519-51065519	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1052A>G; p.D351G; 18:51065519-51065519	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1228_1229insCA; p.Q410fs*6; 18:51067107-51067108	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.131T>G; p.V44G; 18:51047177-51047177	pancreas	carcinoma	Substitution - Missense
c.1546C>T; p.Q516*; 18:51078354-51078354	large_intestine; rectum	other; ulcerative_colitis	Substitution - Nonsense
c.1052A>G; p.D351G; 18:51065519-51065519	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1592delG; p.A532fs*5; 18:51078400-51078400	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1052A>G; p.D351G; 18:51065519-51065519	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1052A>G; p.D351G; 18:51065519-51065519	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1052A>G; p.D351G; 18:51065519-51065519	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.305C>T; p.P102L; 18:51048741-51048741	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.692_693insC; p.S232fs*3; 18:51058149-51058150	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.1610A>G; p.D537G; 18:51078418-51078418	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1447+1G>T; p.?; 18:51076777-51076777	pancreas	carcinoma	Unknown
c.1447+1G>T; p.?; 18:51076777-51076777	pancreas	carcinoma	Unknown
c.1619T>C; p.L540P; 18:51078427-51078427	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.117A>G; p.A39A; 18:51047163-51047163	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1162C>T; p.Q388*; 18:51067041-51067041	pancreas	carcinoma	Substitution - Nonsense
c.366_367insA; p.C123fs*2; 18:51048802-51048803	pancreas	NS	Insertion - Frameshift
c.1512T>C; p.S504S; 18:51078320-51078320	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1512T>C; p.S504S; 18:51078320-51078320	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1512T>C; p.S504S; 18:51078320-51078320	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.256G>T; p.G86C; 18:51048692-51048692	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1447+1G>A; p.?; 18:51076777-51076777	pancreas	carcinoma; ductal_carcinoma	Unknown
c.1572G>C; p.W524C; 18:51078380-51078380	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1447+1G>A; p.?; 18:51076777-51076777	pancreas	carcinoma; ductal_carcinoma	Unknown
c.1284G>T; p.K428N; 18:51067163-51067163	pancreas	carcinoma	Substitution - Missense
c.1572G>C; p.W524C; 18:51078380-51078380	pancreas	carcinoma	Substitution - Missense
c.1009G>T; p.E337*; 18:51065476-51065476	pancreas	carcinoma	Substitution - Nonsense
c.283T>C; p.Y95H; 18:51048719-51048719	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.533C>G; p.S178*; 18:51054859-51054859	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Nonsense
c.1049T>A; p.V350D; 18:51065516-51065516	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.804delG; p.W268fs*1; 18:51058356-51058356	pancreas	NS	Deletion - Frameshift
c.1333C>A; p.R445R; 18:51076662-51076662	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.995A>G; p.D332G; 18:51065462-51065462	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.121G>T; p.E41*; 18:51047167-51047167	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1592G>A; p.R531Q; 18:51078400-51078400	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1592G>A; p.R531Q; 18:51078400-51078400	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1592G>A; p.R531Q; 18:51078400-51078400	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1592G>A; p.R531Q; 18:51078400-51078400	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1135G>A; p.A379T; 18:51065602-51065602	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.306T>C; p.P102P; 18:51048742-51048742	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1495T>C; p.C499R; 18:51078303-51078303	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.306T>C; p.P102P; 18:51048742-51048742	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.740G>A; p.G247E; 18:51058197-51058197	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.306T>C; p.P102P; 18:51048742-51048742	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.919G>T; p.E307*; 18:51059880-51059880	pancreas	carcinoma	Substitution - Nonsense
c.1571G>A; p.W524*; 18:51078379-51078379	pancreas	carcinoma	Substitution - Nonsense
c.565C>T; p.R189C; 18:51054891-51054891	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1495T>C; p.C499R; 18:51078303-51078303	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.432A>T; p.S144S; 18:51049302-51049302	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1508_1509insT; p.M503fs*24; 18:51078316-51078317	pancreas	NS	Insertion - Frameshift
c.1217C>T; p.A406V; 18:51067096-51067096	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.432A>T; p.S144S; 18:51049302-51049302	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1217C>T; p.A406V; 18:51067096-51067096	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1648C>A; p.P550T; 18:51078456-51078456	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1148T>C; p.I383T; 18:51067027-51067027	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.432A>T; p.S144S; 18:51049302-51049302	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1323T>C; p.R441R; 18:51076652-51076652	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1082G>C; p.R361P; 18:51065549-51065549	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1323T>C; p.R441R; 18:51076652-51076652	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1323T>C; p.R441R; 18:51076652-51076652	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1297G>A; p.A433T; 18:51067176-51067176	biliary_tract; bile_duct	carcinoma	Substitution - Missense
c.1323T>C; p.R441R; 18:51076652-51076652	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.354G>A; p.A118A; 18:51048790-51048790	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1487G>A; p.R496H; 18:51078295-51078295	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1609G>C; p.D537H; 18:51078417-51078417	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1609G>C; p.D537H; 18:51078417-51078417	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.389C>A; p.P130Q; 18:51048825-51048825	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.226A>G; p.R76G; 18:51047272-51047272	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1487G>A; p.R496H; 18:51078295-51078295	thyroid	carcinoma; papillary_carcinoma	Substitution - Missense
c.1487G>A; p.R496H; 18:51078295-51078295	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1487G>A; p.R496H; 18:51078295-51078295	pancreas	carcinoma	Substitution - Missense
c.1609G>C; p.D537H; 18:51078417-51078417	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.404G>A; p.R135Q; 18:51048840-51048840	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.346C>T; p.Q116*; 18:51048782-51048782	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1259G>A; p.R420H; 18:51067138-51067138	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1084_1085ins37; p.F362fs*2; 18:51065551-51065552	stomach	carcinoma; adenocarcinoma	Insertion - Frameshift
c.346C>T; p.Q116*; 18:51048782-51048782	pancreas	carcinoma	Substitution - Nonsense
c.346C>T; p.Q116*; 18:51048782-51048782	pancreas	NS	Substitution - Nonsense
c.346C>T; p.Q116*; 18:51048782-51048782	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.547C>T; p.Q183*; 18:51054873-51054873	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1287C>T; p.I429I; 18:51067166-51067166	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1525T>C; p.W509R; 18:51078333-51078333	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.547C>T; p.Q183*; 18:51054873-51054873	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1158T>C; p.G386G; 18:51067037-51067037	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1525T>C; p.W509R; 18:51078333-51078333	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1525T>C; p.W509R; 18:51078333-51078333	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.972T>C; p.C324C; 18:51065439-51065439	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1248A>G; p.R416R; 18:51067127-51067127	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1156G>C; p.G386R; 18:51067035-51067035	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.292C>T; p.L98F; 18:51048728-51048728	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.972T>C; p.C324C; 18:51065439-51065439	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1156G>C; p.G386R; 18:51067035-51067035	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1156G>C; p.G386R; 18:51067035-51067035	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1156G>C; p.G386R; 18:51067035-51067035	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.972T>C; p.C324C; 18:51065439-51065439	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1248A>G; p.R416R; 18:51067127-51067127	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.283T>A; p.Y95N; 18:51048719-51048719	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1248A>G; p.R416R; 18:51067127-51067127	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1156G>C; p.G386R; 18:51067035-51067035	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.972T>C; p.C324C; 18:51065439-51065439	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1013C>A; p.T338K; 18:51065480-51065480	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.961G>A; p.E321K; 18:51065428-51065428	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.265G>T; p.G89*; 18:51048701-51048701	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.989A>C; p.E330A; 18:51065456-51065456	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.989A>C; p.E330A; 18:51065456-51065456	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.742C>T; p.Q248*; 18:51058199-51058199	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1057T>C; p.Y353H; 18:51065524-51065524	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1496G>A; p.C499Y; 18:51078304-51078304	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1140-2A>C; p.?; 18:51067017-51067017	pancreas	carcinoma	Unknown
c.1496G>A; p.C499Y; 18:51078304-51078304	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.742C>T; p.Q248*; 18:51058199-51058199	pancreas	carcinoma	Substitution - Nonsense
c.1600C>T; p.Q534*; 18:51078408-51078408	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Nonsense
c.1496G>A; p.C499Y; 18:51078304-51078304	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1600C>T; p.Q534*; 18:51078408-51078408	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1067C>T; p.P356L; 18:51065534-51065534	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1067C>T; p.P356L; 18:51065534-51065534	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1067C>T; p.P356L; 18:51065534-51065534	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.932A>G; p.Q311R; 18:51059893-51059893	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1477G>C; p.D493H; 18:51078285-51078285	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1067C>T; p.P356L; 18:51065534-51065534	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1067C>T; p.P356L; 18:51065534-51065534	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1659A>C; p.*553C; 18:51078467-51078467	large_intestine; caecum	carcinoma; adenocarcinoma	Nonstop extension
c.1067C>T; p.P356L; 18:51065534-51065534	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1067C>T; p.P356L; 18:51065534-51065534	large_intestine; appendix	carcinoma; adenocarcinoma	Substitution - Missense
c.1555delA; p.E520fs*17; 18:51078363-51078363	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Deletion - Frameshift
c.425-9A>G; p.?; 18:51049286-51049286	large_intestine	carcinoma; adenocarcinoma	Unknown
c.1224T>C; p.F408F; 18:51067103-51067103	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1081C>T; p.R361C; 18:51065548-51065548	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	pancreas	carcinoma	Substitution - Missense
c.1107_1112delTGTCCA; p.V370_H371del; 18:51065574-51065579	large_intestine	carcinoma; adenocarcinoma	Deletion - In frame
c.1310T>A; p.V437D; 18:51076639-51076639	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	small_intestine; jejunum	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	small_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	small_intestine; duodenum	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	pancreas; ampulla_of_Vater	carcinoma; ductal_carcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	small_intestine; duodenum	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	small_intestine; duodenum	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	pancreas	carcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	pancreas	carcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1081C>T; p.R361C; 18:51065548-51065548	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.942T>C; p.I314I; 18:51059903-51059903	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1168G>T; p.E390*; 18:51067047-51067047	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.905-1G>T; p.?; 18:51059865-51059865	large_intestine	carcinoma; adenocarcinoma	Unknown
c.1510A>G; p.S504G; 18:51078318-51078318	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1058A>G; p.Y353C; 18:51065525-51065525	small_intestine; duodenum	carcinoma; adenocarcinoma	Substitution - Missense
c.1510A>G; p.S504G; 18:51078318-51078318	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1058A>G; p.Y353C; 18:51065525-51065525	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1570T>C; p.W524R; 18:51078378-51078378	pancreas	carcinoma	Substitution - Missense
c.1258C>A; p.R420S; 18:51067137-51067137	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

Mutation summary in protein domains

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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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Loss of Function mutations compare to missense mutations

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The copy number variations for various cancers

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COSMIC somatic mutation [Top]