Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
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Found 476 literature records
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Entrez ID
Description
5887
RAD23B has a potential role in breast cancer progression and a tumor suppressor role of nuclear RAD23B in breast cancer.
4862
"NPAS2, functioned as a potential tumor suppressor gene, could serve as a promising target and potential prognostic indicator for colorectal cancer."
84446
BRSK1 is a novel tumor suppressor in breast cancer which inversely correlated with Jab1 expression.
64326
Phosphorylation of the ETS1 and ETS2 transcriptional oncoproteins at specific serine or threonine residues creates binding sites for the COP1 tumor suppressor protein.
2170
"Tumor suppressor activity of the gene encoding mammary-derived growth inhibitor. The gene encoding mammary-derived growth inhibitor (MDGI), a protein previously purified from bovine mammary gland and shown to have modest antiproliferative activity for human breast cancer cells in vitro, is demonstrated to function as a potent tumor suppressor gene. "
5268
The tumor suppressor maspin does not undergo the stressed to relaxed transition or inhibit trypsin-like serine proteases. Evidence that maspin is not a protease inhibitory serpin.
1801
"Identification of two candidate tumor suppressor genes on chromosome 17p13.3. Using allelic loss mapping and positional cloning methods, we have recently identified two novel genes, which we refer to as OVCA1 and OVCA2, that map to 17p13.3."
672
Antisense RNA to the putative tumor suppressor gene BRCA1 transforms mouse fibroblasts.
3482
M6P/IGF2 receptor: a candidate breast tumor suppressor gene.
1026
The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse.
672
The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse.
7157
The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse.
274
A nucleocytosolic myc-interacting isoform of Bin1 has properties of a tumor suppressor.
5268
mMaspin: the mouse homolog of a human tumor suppressor gene inhibits mammary tumor invasion and motility.
6416
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor.
5268
Tissue-type plasminogen activator is a target of the tumor suppressor gene maspin.
6273
Repression of the candidate tumor suppressor gene S100A2 in breast cancer is mediated by site-specific hypermethylation.
3090
Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer.
6416
"Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene."
7251
Aberrant splicing of the TSG101 tumor suppressor gene in human breast and ovarian cancers.
672
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells.
675
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells.
5655
The role for NES1 serine protease as a novel tumor suppressor.
5920
Identification and characterization of a retinoid-induced class II tumor suppressor/growth regulatory gene.
9077
"NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas."
441951
"We propose a functional role for Zfas1/ ZFAS1 in the regulation of alveolar development and epithelial cell differentiation in the mammary gland, which, together with its dysregulation in human breast cancer, suggests ZFAS1 as a putative tumor suppressor gene."
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