Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase

Found 181 literature records

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Entrez IDDescription
8678"Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21."
274Loss of heterozygosity and tumor suppressor activity of Bin1 in prostate carcinoma.
310"ANX7, a candidate tumor suppressor gene for prostate cancer."
199731"Isolation of the TSLL1 and TSLL2 genes, members of the tumor suppressor TSLC1 gene family encoding transmembrane proteins."
5728Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression.
1316data suggest that KLF6 is a tumor suppressor gene involved in human prostate cancer
1050may function as a tumor suppressor that is mutated during tumorigenesis. Abnormalties in C/EBPalpha function contribute to the development of malignancies in a variety of tisues.
6767"Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer."
634inhibition of prostate tumor angiogenesis by the tumor suppressor CEACAM1
5728MMAC/PTEN tumor suppressor gene regulates vascular endothelial growth factor-mediated angiogenesis in prostate cancer.
4089Differential modulation of androgen receptor-mediated transactivation by Smad3 and tumor suppressor Smad4.
153090Epigenetic regulation of this novel tumor suppressor gene in prostate cancer cell lines.
6041"Author reviews the tumor suppressor role of RNase L, proposing that it functions in counteracting prostate cancer by virtue of its ability to degrade RNA, thus initiating a cellular stress response that leads to apoptosis."
665"Analysis of the candidate 8p21 tumour suppressor, BNIP3L, in breast and ovarian cancer."
10395"Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers."
283518the primary characterization of a new gene KCNRG mapped at chromosome band 13q14.3; is a candidate for a B-cell chronic lymphocytic leukemia and prostate cancer tumor suppressor gene
688Gene deletion and loss of expression and cell growth suppression indicate that KLF5 may be tumor suppressor gene at 13q21 in prostate cancer. Mutation and promoter methylation do not commonly inactivate KLF5 in prostate cancer.
1316"KLF6, a putative tumor suppressor gene, is mutated in astrocytic gliomas."
55840U19 is growth inhibitory and tumor suppressive and that the disruption of androgen-dependent growth inhibition via U19 down-regulation is commonly associated with prostate cancer progression.
5728Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer.
122953c-Jun dimerization protein 2 inhibits cell transformation and has a role as a tumor suppressor gene
5655"The normal epithelial cell-specific 1 (NES1) gene, a candidate tumor suppressor gene on chromosome 19q13.3-4, is downregulated by hypermethylation in acute lymphoblastic leukemia."
6041RNASEL may function as a tumor suppressor in prostate cancer.
5268Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
7490"Suppression of prostate tumor cell growth in vivo by WT1, the Wilms' tumor suppressor gene."
11010"RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer."
5371Loss of the tumor suppressor PML in human cancers of multiple histologic origins.
387496RASL11A is down-regulated in prostate tumors as measured by quantitative real-time PCR. This result suggests that this gene may have a tumor suppressor role in prostate cancer.
1316Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer.
171024myopodin functions as a tumor suppressor gene to limit the growth and to inhibit the metastasis of cancer cells
1316Transcriptional activation of the insulin-like growth factor I receptor gene by the Kruppel-like factor 6 (KLF6) tumor suppressor protein.
26524The LATS2/KPM tumor suppressor is a negative regulator of the androgen receptor.
79893LCRG1 is a novel gene localized to the tumor suppressor locus D17S800-D17S930 involved in laryngeal carcinoma.
5728Regulation of androgen receptor signaling by PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor through distinct mechanisms in prostate cancer cells.
4824NKX3.1 does not function as a typical tumor suppressor protein in prostate cancer but it may still have important regulatory roles during prostate cancer progression
5728The Tumor suppressor PTEN was involved in control of VEGF/VEGFR-2 stimulated prostate cancer cell adhesion as well as proliferation.
9547The finding that CXCL14 expression inhibits prostate tumor growth suggests this gene has tumor suppressive functions.
1316A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk.
10253hSPRY2 is a potential tumor suppressor locus in a prostate cancer cell line.
390RhoE is a tumor suppressor gene that is downregulated early in the development of prostate cancer
7157demonstrated that epigallocatechin-3-gallate activates growth arrest and apoptosis primarily via tumor suppressor p53-dependent pathway that involves the function of both p21 protein and Bax protein
857"Cav-1 functions as a tumor promoter during prostate carcinogenesis, rather than as a tumor suppressor"
7157"observations indicate that p53 tumor suppressor , acting through suppression of nuclear factor kappa B, plays the role of a general ""buffer"" of innate immune response in vivo"
5728"We demonstrate that the expression of the tumor suppressor gene PTEN has a significant inverse correlation with fatty acid synthase (FAS) expression in prostate cancer, and inhibition of the PTEN gene leads to the overexpression of FAS in vitro."
1316Absence of mutation in the putative tumor-suppressor gene KLF6 in colorectal cancers.
8854The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer.
199731"Cell adhesion and prostate tumor-suppressor activity of TSLL2/IGSF4C, an immunoglobulin superfamily molecule homologous to TSLC1/IGSF4"
23541"TAP not only mediates vitamin E absorption to facilitate vitamin E antiproliferation effect in prostate cancer cells, but also functions like a tumor suppressor gene to control cancer cell viability through a non-vitamin E manner."
51741Activated tyrosine kinase Ack1 promotes prostate tumorigenesis by tyrosine phosphorylation of tumor suppressor Wwox at Tyr-287. It leads to polyubiquitination and degradation.
4804The p75(NTR) tumor suppressor induces cell cycle arrest facilitating caspase mediated apoptosis in prostate tumor cells.


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