|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 11191 |
Name | PTENP1 |
Synonym | PTEN-rs|PTEN2|PTH2|psiPTEN;phosphatase and tensin homolog pseudogene 1;PTENP1;phosphatase and tensin homolog pseudogene 1 |
Definition | - |
Position | 9p21 |
Gene Type | pseudo |
Source | Count: 1; Pubmed_search |
Literature support | Count: 2 PubMed records as below. |
|
Evidence Status |
Description |
reviewed | "PTENP1 is a highly homologous processed pseudogene of the tumor suppressor gene PTEN (MIM 601728) that itself exerts a tumor suppressive function by acting as a decoy for PTEN-targeting miRNAs . As a model for the protein-coding-independent role of RNAs, we describe the functional relationship between the mRNAs produced by the PTEN tumour suppressor gene and its pseudogene PTENP1 and the critical consequences of this interaction. We find that PTENP1 is biologically active as it can regulate cellular levels of PTEN and exert a growth-suppressive role." |
reviewed | "In this review, author summarized the gene as tumor suppressor in table 2." |
| More detail of all 2 literatures about PTENP1 | |
|
External Links |
|
Links to Entrez Gene | 11191 |
Links to all GeneRIF Items | 11191 |
Links to iHOP | 11191 |
|
Sequence Information |
|
Nucleotide Sequence |
>11191 : length: 3932 agatgagagacagagacggcggcggcggcggcggcccggcccggcccggcctgaagcccc tctcagcaacccgtgagcatccgcgggggcggcgccggcagcggcggcgtttctcgcttc ttcttcgtcttttctaactgtgcagcctcttcctcggcttctcctgaaagggaaggtgga agccgtgggcttgggcgggagccggctgaggcgcggcggcggcggcacctccccctcctg gagcggggggagaagcggcggcggcggcgcccccggtggccccggcggctgcagctccag ggagggggtctgagtcgcctgtcaccatttccagggctgggaacgccggagagttggtct ctccccttctactgcctccaacacggcggcggcggcggcggcggcggcggcacatggagg gacccgggccggttttaaacctctcgtccgccgccgccgcaccccccgtggcccgggctc cggaggccgctggaggaggcagccgttcggaggattattcgtcttctccccattccgctg ccgccgctgccaggcctctggctgctgaggagaagcaggcccagtagctgccaccatcca gcagctgctgccgcagccattacccggctgcggtccagagccaagcagcggctgagcgag gggcatcagctaccgccaagtccagagccatttccatcctgcagagccccgccaccagca gcttctgccatctctctcctcctttttcttcagccacaggctcccagacaggacagccat catcaaagagatcgttagcagaaacaaaaggagatatcaagaggatggattcgacttaga cttgacctatatttatctaaacattattgctatgggatttcctgcagaaagacttgaagg cgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaagcataaaaacca ttacaagatacacaatctttgtgctgaaagacattatgacaccgccaaatctaattacag agttgcgcaatatccttttgaagaccataacccaccacagctagaacttatcaaaccctt ttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgcagcaattcactg taaagctggaaagggacgaactggtataatgatttatgcatatttattacatcggggcaa atttttaaaggcacaagaggccctagatttctatggggaagtaaggaccagagacaaaaa gggagtaactattcccagtcagaggcgctatgtgtattactatagctacctggtaaagaa tcatgtggattatagaccagtggcactgttgtttcacaagatgatgtttgaaactattcc aatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagctaaaggtgaagat gtattcctccaattcaggacccacacgatgggaggacaagttcatgtattttgagttccc tcagccgttacctgtgtgtggtgatatcaaagtagagttcttccacaaacagaacaagat gctaaaaaaggacaaaatgtttcacttttgggtaaatacattcttcataccaggaccaga ggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaattgatagcatttg cagtatagagcgtgcagataatgacaaggagtatctagtacttactttaacaaaaaatga tcttgacaaagcaaataaagacaaagccaaccgatacttttctccaaattttaaggtgaa gctgtacttcacaaaaacagtagaggagccgtcaaatccagaggctagcagttcaacttc tgtaacaccagatgttagtgacaatgaacctgatcattatagatattctgacaccactga ctctgatccagagaatgaaccttttgatgaagatcagcatacacaaattacaaaagtctg aatttttttttatcaagagggataaaacaccatgaaaacaaacttgaataaactgaaaag ggacctttttttttaatggcaataggacattgtgtcagattaccagttatagaaacaatt ctcttttcgtgaccaatcttgttttaccctatacatccacagggttttgacacttgttgt ccagttgaaaaaaggttgtgtagctgtgtcatgtatatacctttttgtgtcaaaaggaca tttaaaattcaattaggattaataaagatggcactttcccattttattccagttttataa aaagtggagacagactggtgtgtatacgtaggaattttttccttttgtgttctgtcacca actgaagtggctaaagagctttgtgatatactggttcacatcatacccctttgcacttgt ggcaacagataagtttgcagttagctaagagaagtttctgaagggttttgctgcattctt gcatgtatttgggttaggggaatggagggaatgctcagaaaggaaataattttatgctgg actctggaccatataccatctccagctatttacacacacctttctttagcatgctacagt tattaatctggacattcgaggaattggctgctgtcactgcttgttgttttcgcatttttt taaaagcatattggtgctagaaaaggcagctaaaggaagtgaatctgtattggggtacag gaatgaaccttctgcaacatcttaagatccacaaatgaagggatataaaaataatgtcat agataagaaacacagcaacaatgacttaaccatataaatgtggaggctatcaacaaagaa tgggcttgaaacattataaaaattgacaatgatttgttaaatatgttttcttaattgtaa cgacttctccatctcctgtgtaatcaaggccagtgctgaaagtcagatgctattagtacc tacatcagtcaacaacttacacttattttactagttttcaatcatatacctgctgtgaat gcttcatgtgctgcctgcaagcttcttttttctcattaaatataaaatattttgtaatgc taaaaaaaaaaaaaagaacatagaagacaaacatcagaaataaacccatccactatggtt aactcatttttgaatatggtgtaaagtcagtttaatgatgaaataatattattttcaaca aatagtacagaaattaaactatgcaaaaatactattaataatgatgttggatcattacct cacaccatacccccaaattaactcagaacatggcatacaccaaatataagagcaaaaact atgaaatttctagaagaagacagaaaaaaaattatgactttggcttagttgtttcttaga agtaacaggaaaagcataattcataaaagataaattgaaaaatcggacgtcatcaaaata aaaaatggtttatcttcaaagtcacctgttaagaaaatgagaagacaaatcataaagcag ggagaaatttttgaaagtcatgtatctgataagggacagttaaaactaaataaaaacaca aaccatccaattaaaatgaataaagggttcgaataggtatgtcatcagagatcatatagg aataaccaataagcaaacaaaagatgttcaatatcattagttattagagaaacaaaattt aaaaaccacaatgagatgacactacacatttgccagaatgatgattattaaaaaagacca agtattggagaggatgtgaaaaaactggaacctcacacattgacgatagaaatgtaaaat gaaatagccaattcagaaaacattttacaagttttctttgtttttgtttttaatttatta tacccttaccctatgactcagtaattccacttctagatacctaccaaataaaattaaagt ttataacttcacaaagaaaaaaaaaaaaaaaa |