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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 150094 |
Name | SIK1 |
Synonym | MSK|SIK|SNF1LK;salt-inducible kinase 1;SIK1;salt-inducible kinase 1 |
Definition | SIK-1|SNF1-like kinase|myocardial SNF1-like kinase|salt-inducible protein kinase 1|serine/threonine protein kinase|serine/threonine-protein kinase SIK1|serine/threonine-protein kinase SNF1-like kinase 1|serine/threonine-protein kinase SNF1LK |
Position | 21q22.3 |
Gene Type | protein-coding |
Source | Count: 2; Generif,UniProt |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | "activation of the RhoA-ROCK-p38MAPK-MSK signaling pathway is essential for the regulation of the phenotype and of the CST5/cystatin D candidate tumor suppressor and other target genes by 1,25(OH)2D3 in colon cancer cells". |
| More detail of all 1 literatures about SIK1 | |
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Pathways and Diseases |
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Pathway | LKB1 signaling events;PID Curated;200061 |
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External Links |
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Links to Entrez Gene | 150094 |
Links to all GeneRIF Items | 150094 |
Links to iHOP | 150094 |
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Sequence Information |
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Nucleotide Sequence |
>150094 : length: 2352 atggttatcatgtcggagttcagcgcggaccccgcgggccagggtcagggccagcagaag cccctccgggtgggtttttacgacatcgagcggaccctgggcaaaggcaacttcgcggtg gtgaagctggcgcggcatcgagtcaccaaaacgcaggttgcaataaaaataattgataaa acacgattagattcaagcaatttggagaaaatctatcgtgaggttcagctgatgaagctt ctgaaccatccacacatcataaagctttaccaggttatggaaacaaaggacatgctttac atcgtcactgaatttgctaaaaatggagaaatgtttgattatttgacttccaacgggcac ctgagtgagaacgaggcgcggaagaagttctggcaaatcctgtcggccgtggagtactgt cacgaccatcacatcgtccaccgggacctcaagaccgagaacctcctgctggatggcaac atggacatcaagctggcagattttggatttgggaatttctacaagtcaggagagcctctg tccacgtggtgtgggagccccccgtatgccgccccggaagtctttgaggggaaggagtat gaaggcccccagctggacatctggagcctgggcgtggtgctgtacgtcctggtctgcggt tctctccccttcgatgggcctaacctgccgacgctgagacagcgggtgctggagggccgc ttccgcatccccttcttcatgtctcaagactgtgagagcctgatccgccgcatgctggtg gtggaccccgccaggcgcatcaccatcgcccagatccggcagcaccggtggatgcgggct gagccctgcttgccgggacccgcctgccccgccttctccgcacacagctacacctccaac ctgggcgactacgatgagcaggcgctgggtatcatgcagaccctgggcgtggaccggcag aggacggtggagtcactgcaaaacagcagctataaccactttgctgccatttattacctc ctccttgagcggctcaaggagtatcggaatgcccagtgcgcccgccccgggcctgccagg cagccgcggcctcggagctcggacctcagtggtttggaggtgcctcaggaaggtctttcc accgaccctttccgacctgccttgctgtgcccgcagccgcagaccttggtgcagtccgtc ctccaggccgagatggactgtgagctccagagctcgctgcagtggcccttgttcttcccg gtggatgccagctgcagcggagtgttccggccccggcccgtgtccccaagcagcctgctg gacacagccatcagtgaggaggccaggcaggggccgggcctagaggaggagcaggacacg caggagtccctgcccagcagcacgggccggaggcacaccctggccgaggtctccacccgc ctctccccactcaccgcgccatgtatagtcgtctccccctccaccacggcaagtcctgca gagggaaccagctctgacagttgtctgaccttctctgcgagcaaaagccccgcggggctc agtggcaccccggccactcaggggctgctgggcgcctgctccccggtcaggctggcctcg cccttcctggggtcgcagtccgccaccccagtgctgcaggctcaggggggcttgggagga gctgttctgctccctgtcagcttccaggagggacggcgggcgtcggacacctcactgact caagggctgaaggcctttcggcagcagctgaggaagaccacgcggaccaaagggtttctg ggactgaacaaaatcaaggggctggctcgccaggtgtgccaggcccccgccagccgggcc agcaggggcggcctgagccccttccacgcccctgcacagagcccaggcctgcacggcggc gcagccggcagccgggagggctggagcctgctggaggaggtgctagagcagcagaggctg ctccagttacagcaccacccggccgctgcacccggctgctcccaggccccccagccggcc cctgccccgtttgtgatcgccccctgtgatggccctggggctgccccgctccccagcacc ctcctcacgtcggggctcccgctgctgccgcccccactcctgcagaccggcgcgtccccg gtggcctcagcggcgcagctcctggacacacacctgcacattggcaccggccccaccgcc ctccccgctgtgcccccaccacgcctggccaggctggccccaggttgtgagcccctgggg ctgctgcagggggactgtgagatggaggacctgatgccctgctccctaggcacgtttgtc ctggtgcagtga |
Protein Sequence |
>150094 : length: 783 MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK TRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGH LSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPL STWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGR FRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSN LGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQCARPGPAR QPRPRSSDLSGLEVPQEGLSTDPFRPALLCPQPQTLVQSVLQAEMDCELQSSLQWPLFFP VDASCSGVFRPRPVSPSSLLDTAISEEARQGPGLEEEQDTQESLPSSTGRRHTLAEVSTR LSPLTAPCIVVSPSTTASPAEGTSSDSCLTFSASKSPAGLSGTPATQGLLGACSPVRLAS PFLGSQSATPVLQAQGGLGGAVLLPVSFQEGRRASDTSLTQGLKAFRQQLRKTTRTKGFL GLNKIKGLARQVCQAPASRASRGGLSPFHAPAQSPGLHGGAAGSREGWSLLEEVLEQQRL LQLQHHPAAAPGCSQAPQPAPAPFVIAPCDGPGAAPLPSTLLTSGLPLLPPPLLQTGASP VASAAQLLDTHLHIGTGPTALPAVPPPRLARLAPGCEPLGLLQGDCEMEDLMPCSLGTFV LVQ |