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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5216 |
Name | PFN1 |
Synonym | -;profilin 1;PFN1;profilin 1 |
Definition | profilin I|profilin-1 |
Position | 17p13.3 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
reviewed | tumor suppressor function of PFN1 requires a functional actin binding site. |
| More detail of all 1 literatures about PFN1 | |
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Pathways and Diseases |
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Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | erk and pi-3 kinase are necessary for collagen binding in corneal epithelia;PID BioCarta;100184 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | rho cell motility signaling pathway;PID BioCarta;100041 |
Pathway | Shigellosis;KEGG PATHWAY;hsa05131 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Cytoskeletal regulation by Rho GTPase;PANTHER;P00016 |
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External Links |
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Links to Entrez Gene | 5216 |
Links to all GeneRIF Items | 5216 |
Links to iHOP | 5216 |
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Sequence Information |
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Nucleotide Sequence |
>5216 : length: 423 atggccgggtggaacgcctacatcgacaacctcatggcggacgggacctgtcaggacgcg gccatcgtgggctacaaggactcgccctccgtctgggccgccgtccccgggaaaacgttc gtcaacatcacgccagctgaggtgggtgtcctggttggcaaagaccggtcaagtttttac gtgaatgggctgacacttgggggccagaaatgttcggtgatccgggactcactgctgcag gatggggaatttagcatggatcttcgtaccaagagcaccggtggggcccccaccttcaat gtcactgtcaccaagactgacaagacgctagtcctgctgatgggcaaagaaggtgtccac ggtggtttgatcaacaagaaatgttatgaaatggcctcccaccttcggcgttcccagtac tga |
Protein Sequence |
>5216 : length: 140 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVH GGLINKKCYEMASHLRRSQY |