General information | Expression | Regulation | Mutation | Interaction

Basic Information
Gene ID	5216
Name	PFN1
Synonymous	-;profilin 1;PFN1;profilin 1
Definition	profilin I\|profilin-1
Position	17p13.3
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Physical Interaction

| Top |

Interaction Type	Interactor	Data Source
interacts with	TLE1	BIOGRID; PUBMED:16169070;
interacts with	NCK1	BIOGRID; PUBMED:9694849;
interacts with	LRIF1	BIOGRID; PUBMED:16169070;
interacts with	C14orf1	BIOGRID; PUBMED:16169070;
interacts with	CRMP1	BIOGRID; PUBMED:16169070;
interacts with	FMNL1	BIOGRID; PUBMED:10958683;
interacts with	GPHN	BIOGRID; PUBMED:9473484;
interacts with	ENAH	BIOGRID; PUBMED:9473484;
interacts with	DLG5	BIOGRID; PUBMED:16169070;
interacts with	RHOQ	BIOGRID; PUBMED:10445846;
interacts with	MLLT4	BIOGRID; PUBMED:10922060;
interacts with	ACTB	BIOGRID; PUBMED:10411937;
interacts with	XPO6	BIOGRID; PUBMED:14592989;
interacts with	VIPR1	BIOGRID; PUBMED:10867004;
interacts with	VASP	BIOGRID; PUBMED:10882740;
interacts with	UNC119	BIOGRID; PUBMED:16169070;
interacts with	WASF1	BIOGRID; PUBMED:9843499;
interacts with	WASL	BIOGRID; PUBMED:10867004;
interacts with	WASL	BIOGRID; PUBMED:9822597;
interacts with	TLE1	HPRD; PUBMED:16169070;
interacts with	MYPOP	HPRD; PUBMED:15615774;
interacts with	LRIF1	HPRD; PUBMED:16169070;
interacts with	C14orf1	HPRD; PUBMED:16169070;
interacts with	CRMP1	HPRD; PUBMED:16169070;
interacts with	FMNL1	HPRD; PUBMED:10958683;
interacts with	GPHN	HPRD; PUBMED:9473484;
interacts with	ENAH	HPRD; PUBMED:15556561;
interacts with	ENAH	HPRD; PUBMED:9473484;
interacts with	DBN1	HPRD; PUBMED:9473484;
interacts with	DLG5	HPRD; PUBMED:16169070;
interacts with	RHOQ	HPRD; PUBMED:10445846;
interacts with	APBB1IP	HPRD; PUBMED:15469846;
interacts with	ACTB	HPRD; PUBMED:10411937;
interacts with	ACTB	HPRD; PUBMED:15556561;
interacts with	ACTA1	HPRD; PUBMED:8413665;
interacts with	WIPF2	HPRD; PUBMED:12213210;
interacts with	XPO6	HPRD; PUBMED:14592989;
interacts with	VASP	HPRD; PUBMED:10882740;
interacts with	UNC119	HPRD; PUBMED:16169070;
interacts with	WASF1	HPRD; PUBMED:9843499;
interacts with	WASL	HPRD; PUBMED:9822597;
interacts with	PIK3R1	HPRD; PUBMED:9801792;
interacts with	CMA1	HPRD; PUBMED:11751973;
interacts with	CKB	INTACT; PUBMED:19338310;
interacts with	LDHB	INTACT; PUBMED:19338310;
interacts with	EEF1D	INTACT; PUBMED:19338310;
interacts with	HSPA8	INTACT; PUBMED:19338310;
interacts with	ENO1	INTACT; PUBMED:19338310;
interacts with	GAPDH	INTACT; PUBMED:19338310;
interacts with	EEF1G	INTACT; PUBMED:19338310;
interacts with	EEF1A1	INTACT; PUBMED:19338310;
interacts with	DAZAP1	INTACT; PUBMED:19338310;
interacts with	RAD51	INTACT; PUBMED:19338310;
interacts with	RAD52	INTACT; PUBMED:19338310;
interacts with	RPA3	INTACT; PUBMED:19338310;
interacts with	YWHAZ	INTACT; PUBMED:19338310;
interacts with	ACTB	INTACT; PUBMED:19338310;
interacts with	ALDOA	INTACT; PUBMED:19338310;
interacts with	YWHAE	INTACT; PUBMED:19338310;
interacts with	PPIA	INTACT; PUBMED:19338310;
interacts with	PRDX2	INTACT; PUBMED:19338310;
interacts with	PRDX1	INTACT; PUBMED:19338310;
interacts with	PRDX6	INTACT; PUBMED:19338310;
interacts with	RPS10	INTACT; PUBMED:19338310;
interacts with	RPS19	INTACT; PUBMED:19338310;
interacts with	SEC13	INTACT; PUBMED:19338310;
interacts with	HSPD1	INTACT; PUBMED:19338310;
interacts with	TLE1	MINT; PUBMED:16169070;
interacts with	LRIF1	MINT; PUBMED:16169070;
interacts with	C14orf1	MINT; PUBMED:16169070;
interacts with	CRMP1	MINT; PUBMED:16169070;
interacts with	DLG5	MINT; PUBMED:16169070;
interacts with	YWHAZ	MINT; PUBMED:15161933;
interacts with	UNC119	MINT; PUBMED:16169070;

Metabolic Interaction

| Top |

There is no record for PFN1

Signaling Interaction

| Top |

Interaction Type	Interactor	Data Source
reacts with	ACTB	IMID; PUBMED:16569658;
reacts with	PFN1	IMID; PUBMED:10508862;
reacts with	PFN1	IMID; PUBMED:16569658;
reacts with	PCLO	IMID; PUBMED:10508862;