Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

5216

Name

PFN1

Synonymous

-;profilin 1;PFN1;profilin 1

Definition

profilin I|profilin-1

Position

17p13.3

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

profilin1(h) + CRMP1(h) <==> profilin1(h):CRMP1(h) (binding)
profilin1(h) + RG4(h) <==> profilin1(h):RG4(h) (binding)
profilin1(h) + RIF1(h) <==> profilin1(h):RIF1(h) (binding)
profilin1(h) + Gephyrin(r) <==> profilin1(h):Gephyrin(r) (binding)
PFN1(h) --> profilin1(h) (expression).
profilin1(h) + Gephyrin(r) <==> profilin1(h):Gephyrin(r) (binding)
profilin1(h) + drebrin-isoformA(r) <==> profilin1(h):drebrin-isoformA(r) (binding)
profilin1(h) + Mena(r) <==> profilin1(h):Mena(r) (binding)
profilin1(h) + drebrin(r) <==> profilin1(h):drebrin(r) (binding)
profilin1(h) + Gephyrin(r) <==> profilin1(h):Gephyrin(r) (binding)
PFN1(h) --> profilin1(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

2N-acetylalanine.Swiss-Prot 53.0
105N6-acetyllysine.Swiss-Prot 53.0
129Phosphotyrosine.Swiss-Prot 53.0
128Phosphotyrosine15592455Phospho.ELM 6.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr17

Promoter: 4792070 - 4794070GSE27584

chr17

Promoter: 4792070 - 4794070Agilent_014791_44K


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