Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

1630

Name

DCC

Synonymous

CRC18|CRCR1|IGDCC1;deleted in colorectal carcinoma;DCC;deleted in colorectal carcinoma

Definition

colorectal cancer suppressor|colorectal tumor suppressor|deleted in colorectal cancer protein|immunoglobulin superfamily DCC subclass member 1|immunoglobulin superfamily, DCC subclass, member 1|netrin receptor DCC|tumor suppressor protein DCC

Position

18q21.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction

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Interaction Type

Interactor

Data Source

interacts with

 MAPK3BIOGRID; PUBMED:11986622;

interacts with

 MAZBIOGRID; PUBMED:11527412;

interacts with

 NCK1BIOGRID; PUBMED:12149262;

interacts with

 NTN1BIOGRID; PUBMED:12810718;

interacts with

 NTN1BIOGRID; PUBMED:9950216;

interacts with

 PTK2BBIOGRID; PUBMED:15494733;

interacts with

 PTK2BIOGRID; PUBMED:15494733;

interacts with

 APPL1BIOGRID; PUBMED:12011067;

interacts with

 CASP3BIOGRID; PUBMED:11248093;

interacts with

 CASP9BIOGRID; PUBMED:11248093;

interacts with

 ARBIOGRID; PUBMED:12864730;

interacts with

 SIAH1BIOGRID; PUBMED:9858595;

interacts with

 MAPK3HPRD; PUBMED:11986622;

interacts with

 MAZHPRD; PUBMED:12509857;

interacts with

 NCK1HPRD; PUBMED:12149262;

interacts with

 NTN1HPRD; PUBMED:9950216;

interacts with

 APPL1HPRD; PUBMED:12011067;

interacts with

 CASP3HPRD; PUBMED:11248093;

interacts with

 CASP9HPRD; PUBMED:11248093;

interacts with

 ADORA2BHPRD; PUBMED:11048721;

interacts with

 PITPNAHPRD; PUBMED:16244667;

interacts with

 SIAH2HPRD; PUBMED:9858595;

interacts with

 SIAH1HPRD; PUBMED:9858595;

Metabolic Interaction

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There is no record for DCC

Signaling Interaction

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Interaction Type

Interactor

Data Source

reacts with

 NCK1NCI_NATURE; PUBMED:12149262;PUBMED:15788770;

reacts with

 MYO10NCI_NATURE; PUBMED:17237772;

reacts with

 NTN1NCI_NATURE; PUBMED:12149262;PUBMED:15788770;

reacts with

 NTN1NCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:15494734;

reacts with

 NTN1NCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:18253061;

reacts with

 NTN1NCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:18253061;PUBMED:15494734;

reacts with

 NTN1NCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:18253061;PUBMED:15557120;PUBMED:15494734;

reacts with

 NTN1NCI_NATURE; PUBMED:15811950;PUBMED:8978605;PUBMED:8861902;PUBMED:8062384;PUBMED:18616430;PUBMED:19543238;PUBMED:11239160;

reacts with

 NTN1NCI_NATURE; PUBMED:16371650;

reacts with

 NTN1NCI_NATURE; PUBMED:16371650;PUBMED:15574733;PUBMED:10399920;

reacts with

 NTN1NCI_NATURE; PUBMED:17237772;

reacts with

 NTN1NCI_NATURE; PUBMED:17251438;

reacts with

 NTN1NCI_NATURE; PUBMED:18066058;PUBMED:14638695;

reacts with

 NTN1NCI_NATURE; PUBMED:19141671;PUBMED:15494733;PUBMED:15494732;PUBMED:15494734;

reacts with

 NTN1NCI_NATURE; PUBMED:20434207;

reacts with

 NTN1NCI_NATURE; PUBMED:9126742;PUBMED:9126743;PUBMED:15574733;PUBMED:10399920;

reacts with

 BCAR1NCI_NATURE; PUBMED:17251438;

reacts with

 ELMO1NCI_NATURE; PUBMED:18066058;PUBMED:14638695;

reacts with

 FYNNCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:15494734;

reacts with

 FYNNCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:18253061;

reacts with

 FYNNCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:18253061;PUBMED:15557120;PUBMED:15494734;

reacts with

 FYNNCI_NATURE; PUBMED:17251438;

reacts with

 FYNNCI_NATURE; PUBMED:19141671;PUBMED:15494733;PUBMED:15494732;PUBMED:15494734;

state change

 FYNNCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:15494734;

reacts with

 DOCK1NCI_NATURE; PUBMED:18066058;PUBMED:14638695;

reacts with

 DCCNCI_NATURE; PUBMED:12149262;PUBMED:15788770;

reacts with

 DCCNCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:15494734;

reacts with

 DCCNCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:18253061;

reacts with

 DCCNCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:18253061;PUBMED:15494734;

reacts with

 DCCNCI_NATURE; PUBMED:15494733;PUBMED:15494732;PUBMED:18253061;PUBMED:15557120;PUBMED:15494734;

reacts with

 DCCNCI_NATURE; PUBMED:15811950;PUBMED:8978605;PUBMED:8861902;PUBMED:8062384;PUBMED:18616430;PUBMED:19543238;PUBMED:11239160;

reacts with

 DCCNCI_NATURE; PUBMED:16371650;

reacts with

 DCCNCI_NATURE; PUBMED:16371650;PUBMED:15574733;PUBMED:10399920;

reacts with

 DCCNCI_NATURE; PUBMED:17237772;

reacts with

 DCCNCI_NATURE; PUBMED:17251438;

reacts with

 DCCNCI_NATURE; PUBMED:18066058;PUBMED:14638695;

reacts with

 DCCNCI_NATURE; PUBMED:19141671;PUBMED:15494733;PUBMED:15494732;PUBMED:15494734;

reacts with

 DCCNCI_NATURE; PUBMED:20434207;

reacts with

 DCCNCI_NATURE; PUBMED:9126742;PUBMED:9126743;PUBMED:15574733;PUBMED:10399920;

reacts with

 UNC5CNCI_NATURE; PUBMED:16371650;

reacts with

 UNC5CNCI_NATURE; PUBMED:16371650;PUBMED:15574733;PUBMED:10399920;

reacts with

 UNC5ANCI_NATURE; PUBMED:9126742;PUBMED:9126743;PUBMED:15574733;PUBMED:10399920;

reacts with

 UNC5BNCI_NATURE; PUBMED:9126742;PUBMED:9126743;PUBMED:15574733;PUBMED:10399920;

reacts with

 PAK1NCI_NATURE; PUBMED:12149262;PUBMED:15788770;

reacts with

 NCK1REACTOME; PUBMED:10995436;PUBMED:15040784;

reacts with

 NCK1REACTOME; PUBMED:12149262;

reacts with

 NCK1REACTOME; PUBMED:15788770;PUBMED:11817894;

reacts with

 NCK1REACTOME; PUBMED:15960985;PUBMED:12526772;PUBMED:15923631;

reacts with

 NCK1REACTOME; PUBMED:18066058;PUBMED:18212043;

reacts with

 NCK1REACTOME; PUBMED:18066058;PUBMED:18212043;PUBMED:12149262;PUBMED:15788770;PUBMED:11817894;

state change

 NCK1REACTOME; PUBMED:15788770;PUBMED:11817894;

reacts with

 NTN1REACTOME; PUBMED:10995436;PUBMED:15040784;

reacts with

 NTN1REACTOME; PUBMED:11533026;

reacts with

 NTN1REACTOME; PUBMED:12149262;

reacts with

 NTN1REACTOME; PUBMED:15494732;PUBMED:15557120;PUBMED:15494734;

reacts with

 NTN1REACTOME; PUBMED:15494733;

reacts with

 NTN1REACTOME; PUBMED:15494734;

reacts with

 NTN1REACTOME; PUBMED:15788770;PUBMED:11817894;

reacts with

 NTN1REACTOME; PUBMED:15960985;

reacts with

 NTN1REACTOME; PUBMED:15960985;PUBMED:12526772;PUBMED:15923631;

reacts with

 NTN1REACTOME; PUBMED:15960985;PUBMED:15494734;PUBMED:11239160;

reacts with

 NTN1REACTOME; PUBMED:16321979;PUBMED:16244667;

reacts with

 NTN1REACTOME; PUBMED:16371650;PUBMED:11533026;

reacts with

 NTN1REACTOME; PUBMED:18066058;PUBMED:18212043;

reacts with

 NTN1REACTOME; PUBMED:18066058;PUBMED:18212043;PUBMED:12149262;PUBMED:15788770;PUBMED:11817894;

reacts with

 NTN1REACTOME; PUBMED:18253061;PUBMED:15557120;PUBMED:15494734;

reacts with

 NTN1REACTOME; PUBMED:9858595;

reacts with

 NTN1REACTOME; PUBMED:9950216;PUBMED:11239160;

state change

 NTN1REACTOME; PUBMED:15494733;

state change

 NTN1REACTOME; PUBMED:15788770;PUBMED:11817894;

state change

 NTN1REACTOME; PUBMED:18253061;PUBMED:15557120;PUBMED:15494734;

reacts with

 EZRREACTOME; PUBMED:16762451;PUBMED:12154370;

reacts with

 PTK2REACTOME; PUBMED:10995436;PUBMED:15040784;

reacts with

 PTK2REACTOME; PUBMED:11533026;

reacts with

 PTK2REACTOME; PUBMED:12149262;

reacts with

 PTK2REACTOME; PUBMED:15494732;PUBMED:15557120;PUBMED:15494734;

reacts with

 PTK2REACTOME; PUBMED:15494733;

reacts with

 PTK2REACTOME; PUBMED:15494734;

reacts with

 PTK2REACTOME; PUBMED:15788770;PUBMED:11817894;

reacts with

 PTK2REACTOME; PUBMED:15960985;PUBMED:12526772;PUBMED:15923631;

reacts with

 PTK2REACTOME; PUBMED:16371650;PUBMED:11533026;

reacts with

 PTK2REACTOME; PUBMED:18066058;PUBMED:18212043;

reacts with

 PTK2REACTOME; PUBMED:18066058;PUBMED:18212043;PUBMED:12149262;PUBMED:15788770;PUBMED:11817894;

reacts with

 PTK2REACTOME; PUBMED:18253061;PUBMED:15557120;PUBMED:15494734;

state change

 PTK2REACTOME; PUBMED:15494733;

state change

 PTK2REACTOME; PUBMED:15788770;PUBMED:11817894;

state change

 PTK2REACTOME; PUBMED:18253061;PUBMED:15557120;PUBMED:15494734;

reacts with

 DSCAMREACTOME; PUBMED:18585357;

reacts with

 APPL1REACTOME; PUBMED:12011067;PUBMED:11248093;

reacts with

 CASP9REACTOME; PUBMED:12011067;PUBMED:11248093;

reacts with

 DCCREACTOME; PUBMED:10995436;PUBMED:15040784;

reacts with

 DCCREACTOME; PUBMED:11533026;

reacts with

 DCCREACTOME; PUBMED:12011067;PUBMED:11248093;

reacts with

 DCCREACTOME; PUBMED:12149262;

reacts with

 DCCREACTOME; PUBMED:15494732;PUBMED:15557120;PUBMED:15494734;

reacts with

 DCCREACTOME; PUBMED:15494733;

reacts with

 DCCREACTOME; PUBMED:15494734;

reacts with

 DCCREACTOME; PUBMED:15788770;PUBMED:11817894;

reacts with

 DCCREACTOME; PUBMED:15960985;

reacts with

 DCCREACTOME; PUBMED:15960985;PUBMED:12526772;PUBMED:15923631;

reacts with

 DCCREACTOME; PUBMED:15960985;PUBMED:15494734;PUBMED:11239160;

reacts with

 DCCREACTOME; PUBMED:16321979;PUBMED:16244667;

reacts with

 DCCREACTOME; PUBMED:16371650;PUBMED:11533026;

reacts with

 DCCREACTOME; PUBMED:16762451;PUBMED:12154370;

reacts with

 DCCREACTOME; PUBMED:18066058;PUBMED:18212043;

reacts with

 DCCREACTOME; PUBMED:18066058;PUBMED:18212043;PUBMED:12149262;PUBMED:15788770;PUBMED:11817894;

reacts with

 DCCREACTOME; PUBMED:18253061;PUBMED:15557120;PUBMED:15494734;

reacts with

 DCCREACTOME; PUBMED:18585357;

reacts with

 DCCREACTOME; PUBMED:9858595;

reacts with

 DCCREACTOME; PUBMED:9950216;PUBMED:11239160;

state change

 DCCREACTOME; PUBMED:15494733;

state change

 DCCREACTOME; PUBMED:15788770;PUBMED:11817894;

state change

 DCCREACTOME; PUBMED:18253061;PUBMED:15557120;PUBMED:15494734;

reacts with

 RAC1REACTOME; PUBMED:15960985;PUBMED:12526772;PUBMED:15923631;

reacts with

 RAC1REACTOME; PUBMED:18066058;PUBMED:18212043;

reacts with

 PITPNAREACTOME; PUBMED:16321979;PUBMED:16244667;

reacts with

 PLCG1REACTOME; PUBMED:16321979;

reacts with

 PTPN11REACTOME; PUBMED:11533026;

reacts with

 UNC5CREACTOME; PUBMED:11533026;

reacts with

 UNC5CREACTOME; PUBMED:16371650;PUBMED:11533026;

reacts with

 WASLREACTOME; PUBMED:10995436;PUBMED:15040784;

reacts with

 SIAH2REACTOME; PUBMED:9858595;

reacts with

 SIAH1REACTOME; PUBMED:9858595;

reacts with

 CDC42REACTOME; PUBMED:10995436;PUBMED:15040784;

reacts with

 CDC42REACTOME; PUBMED:15788770;PUBMED:11817894;

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