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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 1630 |
Name | DCC |
Synonymous | CRC18|CRCR1|IGDCC1;deleted in colorectal carcinoma;DCC;deleted in colorectal carcinoma |
Definition | colorectal cancer suppressor|colorectal tumor suppressor|deleted in colorectal cancer protein|immunoglobulin superfamily DCC subclass member 1|immunoglobulin superfamily, DCC subclass, member 1|netrin receptor DCC|tumor suppressor protein DCC |
Position | 18q21.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
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Regulation From TransFac database |
DCC(h) + Siah-2(m) <==> DCC(h):Siah-2(m) (binding) | DCC(h) + Siah-2(h) <==> DCC(h):Siah-2(h) (binding) | Siah1(h) --/ DCC(h) (degradation) | Siah-2(h) --/ DCC(h) (degradation) | DCC(h) --> DCC(h) (expression). | DCC(h) --> DCC(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
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Location (AA) |
PTM type |
Literature |
Database |
94 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 299 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 318 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 478 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 628 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 702 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
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Chromosome |
Location |
Source |
|---|---|---|
chr18 |
Promoter: 48119069 - 48121069 | GoldenGate_Methylation_Cancer_Panel_I |
chr18 |
Promoter: 48119069 - 48121069 | GSE27584 |
chr18 |
Promoter: 48119069 - 48121069 | PMID:12374684 |
chr18 |
Promoter: 48119069 - 48121069 | PMID:17018594 |