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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 1958 |
Name | EGR1 |
Synonymous | AT225|G0S30|KROX-24|NGFI-A|TIS8|ZIF-268|ZNF225;early growth response 1;EGR1;early growth response 1 |
Definition | EGR-1|early growth response protein 1|nerve growth factor-induced protein A|transcription factor ETR103|transcription factor Zif268|zinc finger protein 225|zinc finger protein Krox-24 |
Position | 5q31.1 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
interacts with |
TBX2 | BIOGRID; PUBMED:20348948; |
interacts with |
RELA | BIOGRID; PUBMED:10671503; |
interacts with |
NAB1 | BIOGRID; PUBMED:7624335; |
interacts with |
NFATC1 | BIOGRID; PUBMED:12560487; |
interacts with |
NAB2 | BIOGRID; PUBMED:8668170; |
interacts with |
CREBBP | BIOGRID; PUBMED:9806899; |
interacts with |
ERBB3 | BIOGRID; PUBMED:12840049; |
interacts with |
EP300 | BIOGRID; PUBMED:9806899; |
interacts with |
PITX1 | BIOGRID; PUBMED:10082522; |
interacts with |
PFDN5 | BIOGRID; PUBMED:18281035; |
interacts with |
PSMA3 | BIOGRID; PUBMED:12379479; |
interacts with |
SNAI1 | BIOGRID; PUBMED:20121949; |
interacts with |
SREBF2 | BIOGRID; PUBMED:20936779; |
interacts with |
SP1 | BIOGRID; PUBMED:20121949; |
interacts with |
TP53 | BIOGRID; PUBMED:11251186; |
interacts with |
CEBPB | BIOGRID; PUBMED:12947119; |
interacts with |
RELA | HPRD; PUBMED:10671503; |
interacts with |
NAB1 | HPRD; PUBMED:7624335; |
interacts with |
NAB2 | HPRD; PUBMED:8668170; |
interacts with |
CREBBP | HPRD; PUBMED:9806899; |
interacts with |
EP300 | HPRD; PUBMED:9806899; |
interacts with |
CDKN2A | HPRD; PUBMED:19057511; |
interacts with |
CSNK2A1 | HPRD; PUBMED:8662759; |
interacts with |
JUN | HPRD; PUBMED:11278640; |
interacts with |
PITX1 | HPRD; PUBMED:10082522; |
interacts with |
PSMA3 | HPRD; PUBMED:12379479; |
interacts with |
SP1 | HPRD; PUBMED:12569082; |
interacts with |
CEBPB | HPRD; PUBMED:12947119; |
interacts with |
SREBF2 | INTACT; PUBMED:20936779; |
interacts with |
EP300 | MINT; PUBMED:20089040; |
interacts with |
CDKN2A | MINT; PUBMED:19057511; |
interacts with |
SNAI1 | MINT; PUBMED:20121949; |
interacts with |
SP1 | MINT; PUBMED:20121949; |
interacts with |
VDR | MINT; PUBMED:20089040; |
interacts with |
TP53 | MINT; PUBMED:14744935; |
Metabolic Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
metabolic catalysis |
ELK1 | NCI_NATURE; PUBMED:19706684;PUBMED:7958858;PUBMED:2189103;PUBMED:17322878;PUBMED:11029289;PUBMED:11152283;PUBMED:2109185; |
metabolic catalysis |
JUN | NCI_NATURE; PUBMED:18281687; |
metabolic catalysis |
PLCG1 | NCI_NATURE; PUBMED:12367511; |
metabolic catalysis |
SNAI1 | NCI_NATURE; PUBMED:16858414; |
metabolic catalysis |
IRF9 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
metabolic catalysis |
STAT2 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
Signaling Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
EGR1 | NCI_NATURE; PUBMED:12560487; |
reacts with |
ADAR | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
GBP2 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
IFI6 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
IFIT1 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
ISG15 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
RNASEL | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
IFITM2 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
IFIT3 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
IFITM3 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
IFI35 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
ISG20 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
IP6K2 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
IFI27 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
IFITM1 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
IFIT2 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
PSMB8 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |
reacts with |
XAF1 | REACTOME; PUBMED:9096384;PUBMED:1730654;PUBMED:2211721;PUBMED:16009940;PUBMED:6162102;PUBMED:15047845;PUBMED:12766484;PUBMED:11404376;PUBMED:6548414;PUBMED:14769151;PUBMED:12029096;PUBMED:9861020;PUBMED:11337497;PUBMED:11092454; |