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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3661 |
Name | IRF3 |
Synonymous | -;interferon regulatory factor 3;IRF3;interferon regulatory factor 3 |
Definition | - |
Position | 19q13.3-q13.4 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
interacts with |
TANK | BIOGRID; PUBMED:17823124; |
interacts with |
TBK1 | BIOGRID; PUBMED:18636086; |
interacts with |
CREBBP | BIOGRID; PUBMED:10521456; |
interacts with |
EWSR1 | BIOGRID; PUBMED:20211142; |
interacts with |
DDX58 | BIOGRID; PUBMED:18636086; |
interacts with |
IKBKE | BIOGRID; PUBMED:18636086; |
interacts with |
TRIM21 | BIOGRID; PUBMED:19265157; |
interacts with |
IRF5 | BIOGRID; PUBMED:11303025; |
interacts with |
PRDX1 | BIOGRID; PUBMED:16189514; |
interacts with |
IRF7 | BIOGRID; PUBMED:11162841; |
interacts with |
PPIP5K1 | BIOGRID; PUBMED:18636086; |
interacts with |
MAVS | HPRD; PUBMED:16153868; |
interacts with |
TICAM2 | HPRD; PUBMED:14517278; |
interacts with |
TICAM1 | HPRD; PUBMED:14739303; |
interacts with |
TBK1 | HPRD; PUBMED:12692549; |
interacts with |
TBK1 | HPRD; PUBMED:17618271; |
interacts with |
RELA | HPRD; PUBMED:14557267; |
interacts with |
CREBBP | HPRD; PUBMED:10521456; |
interacts with |
GRIP1 | HPRD; PUBMED:16362036; |
interacts with |
EP300 | HPRD; PUBMED:9488451; |
interacts with |
IKBKE | HPRD; PUBMED:12692549; |
interacts with |
IRF5 | HPRD; PUBMED:11303025; |
interacts with |
PIAS4 | HPRD; PUBMED:15251447; |
interacts with |
PRDX1 | HPRD; PUBMED:16189514; |
interacts with |
PPIB | HPRD; PUBMED:15764595; |
interacts with |
IRF7 | HPRD; PUBMED:11162841; |
interacts with |
SYT1 | HPRD; PUBMED:16143103; |
interacts with |
SMURF2 | HPRD; PUBMED:15761153; |
interacts with |
ZBP1 | HPRD; PUBMED:17618271; |
interacts with |
SERPINB2 | HPRD; PUBMED:12883638; |
interacts with |
MAFB | INTACT; PUBMED:20581830; |
interacts with |
TICAM1 | INTACT; PUBMED:15841462; |
interacts with |
TBK1 | INTACT; PUBMED:15841462; |
interacts with |
CREBBP | INTACT; PUBMED:20581830; |
interacts with |
TBK1 | MINT; PUBMED:17599067; |
interacts with |
TBK1 | MINT; PUBMED:18583960; |
interacts with |
NUP62 | MINT; PUBMED:17599067; |
interacts with |
CREBBP | MINT; PUBMED:18309294; |
interacts with |
BAX | MINT; DOI:10.1038/emboj.2010.50; |
interacts with |
GSS | MINT; PUBMED:18309294; |
interacts with |
GRIP1 | MINT; PUBMED:16362036; |
interacts with |
GAPDH | MINT; PUBMED:17599067; |
interacts with |
PIAS4 | MINT; PUBMED:15251447; |
Metabolic Interaction | | Top | |
There is no record for IRF3 |
Signaling Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
IRF3 | REACTOME; PUBMED:12604599; |
reacts with |
IRF3 | REACTOME; PUBMED:16699525;PUBMED:16715065;PUBMED:19125153; |
reacts with |
IRF3 | REACTOME; PUBMED:9541017; |
reacts with |
IRF3 | REACTOME; PUBMED:9541017;PUBMED:9463386;PUBMED:10082512; |
reacts with |
IRF3 | REACTOME; PUBMED:9660935; |
state change |
IRF3 | REACTOME; PUBMED:16914094;PUBMED:20153823;null:null;PUBMED:16699525;PUBMED:16715065;PUBMED:19125153; |
state change |
ISG15 | REACTOME; PUBMED:16914094;PUBMED:20153823;null:null;PUBMED:16699525;PUBMED:16715065;PUBMED:19125153; |
reacts with |
PIN1 | REACTOME; PUBMED:16699525;PUBMED:16715065;PUBMED:19125153; |
reacts with |
IRF7 | REACTOME; PUBMED:12604599; |
reacts with |
IRF7 | REACTOME; PUBMED:9660935; |