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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 3678 |
Name | ITGA5 |
Synonymous | CD49e|FNRA|VLA5A;integrin, alpha 5 (fibronectin receptor, alpha polypeptide);ITGA5;integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
Definition | CD49 antigen-like family member E|VLA-5|fibronectin receptor subunit alpha|fibronectin receptor, alpha subunit|integrin alpha-5|integrin alpha-F|very late activation protein 5, alpha subunit |
Position | 12q11-q13 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
interacts with |
RABIF | BIOGRID; PUBMED:10094488; |
interacts with |
L1CAM | BIOGRID; PUBMED:10871287; |
interacts with |
AUP1 | BIOGRID; PUBMED:12042322; |
interacts with |
GIPC1 | BIOGRID; PUBMED:11479315; |
interacts with |
FN1 | BIOGRID; PUBMED:1532572; |
interacts with |
FGFR2 | BIOGRID; PUBMED:15728256; |
interacts with |
CBL | BIOGRID; PUBMED:15728256; |
interacts with |
ILK | BIOGRID; PUBMED:8538749; |
interacts with |
SPP1 | BIOGRID; PUBMED:7592829; |
interacts with |
CD9 | BIOGRID; PUBMED:10065872; |
interacts with |
TGM2 | HPRD; PUBMED:10684262; |
interacts with |
F2 | HPRD; PUBMED:9864377; |
interacts with |
NISCH | HPRD; PUBMED:15028619; |
interacts with |
LAMA4 | HPRD; PUBMED:12445830; |
interacts with |
PPAP2B | HPRD; PUBMED:16099422; |
interacts with |
L1CAM | HPRD; PUBMED:10871287; |
interacts with |
AUP1 | HPRD; PUBMED:12042322; |
interacts with |
EGFR | HPRD; PUBMED:10888683; |
interacts with |
GIPC1 | HPRD; PUBMED:11479315; |
interacts with |
FGFR2 | HPRD; PUBMED:15728256; |
interacts with |
ERBB2 | HPRD; PUBMED:15757908; |
interacts with |
ITGB3 | HPRD; PUBMED:10684262; |
interacts with |
ITGB3 | HPRD; PUBMED:12445830; |
interacts with |
ITGB3 | HPRD; PUBMED:1694173; |
interacts with |
ITGB3 | HPRD; PUBMED:7532190; |
interacts with |
ITGB3 | HPRD; PUBMED:8387021; |
interacts with |
ITGB3 | HPRD; PUBMED:9864377; |
interacts with |
ITGB6 | HPRD; PUBMED:11668187; |
interacts with |
ITGB5 | HPRD; PUBMED:7592829; |
interacts with |
ARHGAP5 | HPRD; PUBMED:8537347; |
interacts with |
ANGPT1 | HPRD; PUBMED:15781448; |
interacts with |
ANGPTL3 | HPRD; PUBMED:11877390; |
interacts with |
ADAM15 | HPRD; PUBMED:9914169; |
interacts with |
IGFBP2 | HPRD; PUBMED:15171717; |
interacts with |
PECAM1 | HPRD; PUBMED:10982404; |
interacts with |
PECAM1 | HPRD; PUBMED:11149921; |
interacts with |
ITGB1 | HPRD; PUBMED:10684262; |
interacts with |
ITGB1 | HPRD; PUBMED:11149921; |
interacts with |
ITGB1 | HPRD; PUBMED:15171717; |
interacts with |
ITGB1 | HPRD; PUBMED:16055535; |
interacts with |
ITGB1 | HPRD; PUBMED:16099422; |
interacts with |
ITGB1 | HPRD; PUBMED:7504269; |
interacts with |
ITGB1 | HPRD; PUBMED:9914169; |
interacts with |
FLT4 | HPRD; PUBMED:15389531; |
interacts with |
SFRP2 | HPRD; PUBMED:14709558; |
interacts with |
SPP1 | HPRD; PUBMED:7532190; |
interacts with |
SPP1 | HPRD; PUBMED:7592829; |
interacts with |
COL6A3 | HPRD; PUBMED:8387021; |
interacts with |
COL1A1 | HPRD; PUBMED:1693626; |
interacts with |
COL18A1 | HPRD; PUBMED:11158588; |
interacts with |
CD9 | HPRD; PUBMED:10065872; |
interacts with |
FABP3 | INTACT; PUBMED:20802519; |
interacts with |
FN1 | MINT; PUBMED:16457822; |
interacts with |
CTGF | MINT; PUBMED:16457822; |
interacts with |
SDC2 | NCI_NATURE; PUBMED:10772816; |
Metabolic Interaction | | Top | |
There is no record for ITGA5 |
Signaling Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
TEK | NCI_NATURE; PUBMED:17189382; |
reacts with |
FN1 | NCI_NATURE; PUBMED:10744708;PUBMED:15684035;PUBMED:17145753;PUBMED:16547007; |
reacts with |
FN1 | NCI_NATURE; PUBMED:11553610; |
reacts with |
FN1 | NCI_NATURE; PUBMED:15699160;PUBMED:3546305;PUBMED:12119020;PUBMED:11893752;PUBMED:3031508;PUBMED:8566283;PUBMED:15688013;PUBMED:7521847;PUBMED:7551560;PUBMED:7592835; |
state change |
FN1 | NCI_NATURE; PUBMED:17189382; |
reacts with |
FGG | NCI_NATURE; PUBMED:12799374;PUBMED:9030612; |
reacts with |
FBN1 | NCI_NATURE; PUBMED:17158881;PUBMED:12807887; |
reacts with |
FGA | NCI_NATURE; PUBMED:12799374;PUBMED:9030612; |
reacts with |
FGB | NCI_NATURE; PUBMED:12799374;PUBMED:9030612; |
reacts with |
ANGPT1 | NCI_NATURE; PUBMED:17189382; |
reacts with |
ITGA5 | NCI_NATURE; PUBMED:10744708;PUBMED:15684035;PUBMED:17145753;PUBMED:16547007; |
reacts with |
ITGA5 | NCI_NATURE; PUBMED:11553610; |
reacts with |
ITGA5 | NCI_NATURE; PUBMED:12682293; |
reacts with |
ITGA5 | NCI_NATURE; PUBMED:12799374;PUBMED:9030612; |
reacts with |
ITGA5 | NCI_NATURE; PUBMED:14602715;PUBMED:15684035;PUBMED:8703217;PUBMED:17145753;PUBMED:16547007; |
reacts with |
ITGA5 | NCI_NATURE; PUBMED:15699160;PUBMED:3546305;PUBMED:12119020;PUBMED:11893752;PUBMED:3031508;PUBMED:8566283;PUBMED:15688013;PUBMED:7521847;PUBMED:7551560;PUBMED:7592835; |
reacts with |
ITGA5 | NCI_NATURE; PUBMED:17158881;PUBMED:12807887; |
reacts with |
ITGA5 | NCI_NATURE; PUBMED:17189382; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:10744708;PUBMED:15684035;PUBMED:17145753;PUBMED:16547007; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:11553610; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:12682293; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:12799374;PUBMED:9030612; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:14602715;PUBMED:15684035;PUBMED:8703217;PUBMED:17145753;PUBMED:16547007; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:15699160;PUBMED:3546305;PUBMED:12119020;PUBMED:11893752;PUBMED:3031508;PUBMED:8566283;PUBMED:15688013;PUBMED:7521847;PUBMED:7551560;PUBMED:7592835; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:17158881;PUBMED:12807887; |
reacts with |
ITGB1 | NCI_NATURE; PUBMED:17189382; |
reacts with |
PLAU | NCI_NATURE; PUBMED:10744708;PUBMED:15684035;PUBMED:17145753;PUBMED:16547007; |
reacts with |
PLAU | NCI_NATURE; PUBMED:14602715;PUBMED:15684035;PUBMED:8703217;PUBMED:17145753;PUBMED:16547007; |
reacts with |
FLT4 | NCI_NATURE; PUBMED:11553610; |
reacts with |
FIGF | NCI_NATURE; PUBMED:11553610; |
reacts with |
PLAUR | NCI_NATURE; PUBMED:10744708;PUBMED:15684035;PUBMED:17145753;PUBMED:16547007; |
reacts with |
PLAUR | NCI_NATURE; PUBMED:14602715;PUBMED:15684035;PUBMED:8703217;PUBMED:17145753;PUBMED:16547007; |
reacts with |
COL18A1 | NCI_NATURE; PUBMED:12682293; |
reacts with |
FN1 | REACTOME; PUBMED:8314844;PUBMED:17167768;PUBMED:16258728; |
reacts with |
ITGA5 | REACTOME; PUBMED:10673366; |
reacts with |
ITGA5 | REACTOME; PUBMED:8314844;PUBMED:17167768;PUBMED:16258728; |
reacts with |
ITGB1 | REACTOME; PUBMED:10673366; |
reacts with |
ITGB1 | REACTOME; PUBMED:8314844;PUBMED:17167768;PUBMED:16258728; |
reacts with |
SPP1 | REACTOME; PUBMED:10673366; |