Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

3678

Name

ITGA5

Synonymous

CD49e|FNRA|VLA5A;integrin, alpha 5 (fibronectin receptor, alpha polypeptide);ITGA5;integrin, alpha 5 (fibronectin receptor, alpha polypeptide)

Definition

CD49 antigen-like family member E|VLA-5|fibronectin receptor subunit alpha|fibronectin receptor, alpha subunit|integrin alpha-5|integrin alpha-F|very late activation protein 5, alpha subunit

Position

12q11-q13

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

alpha5-integrin(h) + Nischarin(m) <==> alpha5-integrin(h):Nischarin(m) (binding)
IGFBP-2(m.s.) + alpha5-integrin(h) <==> IGFBP-2(m.s.):alpha5-integrin(h) (binding)
alpha5-integrin(h) --> CCND1(h) (transactivation)
Itga5(h) --> alpha5-integrin(h) (expression).
ErbB2(h) + alpha5-integrin(h) <==> ErbB2(h):alpha5-integrin(h) (binding)
alpha5-integrin(h) + ErbB2(h) <==> alpha5-integrin(h):ErbB2(h) (binding)
aup-1-isoformS(h) + alpha5-integrin(h) <==> aup-1-isoformS(h):alpha5-integrin(h) (binding)
Itga5(h) --> alpha5-integrin(h) (expression).

Post Transcriptional Modification From dbPTM

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Location (AA)

PTM type

Literature

Database

84N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
182N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
297N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
307N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
316N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
524N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
530N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
593N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
609N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
675N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
712N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
724N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
773N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
868N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr12

Promoter: 53098817 - 53100817Agilent_014791

chr12

Promoter: 53098817 - 53100817GSE27584

chr12

Promoter: 53098817 - 53100817Agilent_014791_44K

chr12

Promoter: 53098817 - 53100817E-GEOD-20553


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