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General information | Expression | Regulation | Mutation | Interaction |
Basic Information |
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Gene ID | 5071 |
Name | PARK2 |
Synonymous | AR-JP|LPRS2|PDJ|PRKN;parkinson protein 2, E3 ubiquitin protein ligase (parkin);PARK2;parkinson protein 2, E3 ubiquitin protein ligase (parkin) |
Definition | E3 ubiquitin ligase|E3 ubiquitin-protein ligase parkin|Parkinson disease (autosomal recessive, juvenile) 2, parkin|parkin 2|parkinson disease protein 2|parkinson juvenile disease protein 2 |
Position | 6q25.2-q27 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
Interaction Type |
Interactor |
Data Source |
---|---|---|
interacts with |
MFN1 | BIOGRID; PUBMED:21615408; |
interacts with |
MFN2 | BIOGRID; PUBMED:21615408; |
interacts with |
TUBA1A | BIOGRID; PUBMED:16714300; |
interacts with |
TRAF2 | BIOGRID; PUBMED:17314283; |
interacts with |
MAPT | BIOGRID; PUBMED:14962978; |
interacts with |
MAPT | BIOGRID; PUBMED:18248624; |
interacts with |
TUBG1 | BIOGRID; PUBMED:12928331; |
interacts with |
TUBG1 | BIOGRID; PUBMED:16714300; |
interacts with |
GRIN2B | BIOGRID; PUBMED:11679592; |
interacts with |
SLC11A2 | BIOGRID; PUBMED:20089134; |
interacts with |
IKBKG | BIOGRID; PUBMED:17314283; |
interacts with |
NDUFA4L2 | BIOGRID; PUBMED:16169070; |
interacts with |
LIMK1 | BIOGRID; PUBMED:17512523; |
interacts with |
LRRK2 | BIOGRID; PUBMED:16352719; |
interacts with |
Sept5 | BIOGRID; PUBMED:11078524; |
interacts with |
BACH1 | BIOGRID; PUBMED:17682061; |
interacts with |
BCL2 | BIOGRID; PUBMED:20889974; |
interacts with |
GPR37 | BIOGRID; PUBMED:11439185; |
interacts with |
GPR37 | BIOGRID; PUBMED:12150907; |
interacts with |
HOMER1 | BIOGRID; PUBMED:11679592; |
interacts with |
HSPA8 | BIOGRID; PUBMED:12150907; |
interacts with |
HSPA4 | BIOGRID; PUBMED:12676955; |
interacts with |
HSPA4 | BIOGRID; PUBMED:16714300; |
interacts with |
HSPA4 | BIOGRID; PUBMED:18248624; |
interacts with |
HDAC4 | BIOGRID; PUBMED:16332688; |
interacts with |
FBXW7 | BIOGRID; PUBMED:12628165; |
interacts with |
EPS15 | BIOGRID; PUBMED:16862145; |
interacts with |
EP300 | BIOGRID; PUBMED:19297328; |
interacts with |
FBP1 | BIOGRID; PUBMED:16672220; |
interacts with |
CCNA1 | BIOGRID; PUBMED:12628165; |
interacts with |
Eps15 | BIOGRID; PUBMED:16862145; |
interacts with |
Egfr | BIOGRID; PUBMED:16862145; |
interacts with |
DLG4 | BIOGRID; PUBMED:11679592; |
interacts with |
CUL1 | BIOGRID; PUBMED:12628165; |
interacts with |
CASK | BIOGRID; PUBMED:11679592; |
interacts with |
DNAJB1 | BIOGRID; PUBMED:12150907; |
interacts with |
DNAJA1 | BIOGRID; PUBMED:12150907; |
interacts with |
CDK5 | BIOGRID; PUBMED:17327227; |
interacts with |
RAC1 | BIOGRID; PUBMED:16169070; |
interacts with |
RAD1 | BIOGRID; PUBMED:16169070; |
interacts with |
RANBP2 | BIOGRID; PUBMED:16332688; |
interacts with |
RGS2 | BIOGRID; PUBMED:16169070; |
interacts with |
RNF41 | BIOGRID; PUBMED:15632191; |
interacts with |
RNF41 | BIOGRID; PUBMED:18541373; |
interacts with |
AMBRA1 | BIOGRID; PUBMED:21753002; |
interacts with |
APP | BIOGRID; PUBMED:19610108; |
interacts with |
AIMP2 | BIOGRID; PUBMED:12783850; |
interacts with |
AIMP2 | BIOGRID; PUBMED:16049031; |
interacts with |
AIMP2 | BIOGRID; PUBMED:16135753; |
interacts with |
AIMP2 | BIOGRID; PUBMED:16714300; |
interacts with |
ABL1 | BIOGRID; PUBMED:20823226; |
interacts with |
HTRA2 | BIOGRID; PUBMED:19631192; |
interacts with |
PSMC5 | BIOGRID; PUBMED:12676955; |
interacts with |
PLCG1 | BIOGRID; PUBMED:18671761; |
interacts with |
PINK1 | BIOGRID; PUBMED:19358826; |
interacts with |
CAMK2A | BIOGRID; PUBMED:11679592; |
interacts with |
PSMA4 | BIOGRID; PUBMED:15987638; |
interacts with |
PSMA4 | BIOGRID; PUBMED:16714300; |
interacts with |
PICK1 | BIOGRID; PUBMED:17553932; |
interacts with |
PSMA1 | BIOGRID; PUBMED:12150907; |
interacts with |
CCNE1 | BIOGRID; PUBMED:12628165; |
interacts with |
ZNF746 | BIOGRID; PUBMED:21376232; |
interacts with |
SNCA | BIOGRID; PUBMED:11588587; |
interacts with |
SNCA | BIOGRID; PUBMED:16714300; |
interacts with |
SNCA | BIOGRID; PUBMED:18195004; |
interacts with |
SYT11 | BIOGRID; PUBMED:12925569; |
interacts with |
SYN1 | BIOGRID; PUBMED:11431533; |
interacts with |
SNCAIP | BIOGRID; PUBMED:11590439; |
interacts with |
SNCAIP | BIOGRID; PUBMED:15944382; |
interacts with |
SNCAIP | BIOGRID; PUBMED:16049031; |
interacts with |
UBE2L6 | BIOGRID; PUBMED:11078524; |
interacts with |
UBE2G1 | BIOGRID; PUBMED:11439185; |
interacts with |
UBE2J1 | BIOGRID; PUBMED:11439185; |
interacts with |
UBE2L3 | BIOGRID; PUBMED:10973942; |
interacts with |
UBE2L3 | BIOGRID; PUBMED:11431533; |
interacts with |
SIM2 | BIOGRID; PUBMED:15963499; |
interacts with |
SEPT5 | BIOGRID; PUBMED:14559152; |
interacts with |
SEPT5 | BIOGRID; PUBMED:16714300; |
interacts with |
SEPT5 | BIOGRID; PUBMED:18845538; |
interacts with |
SLC6A3 | BIOGRID; PUBMED:15492001; |
interacts with |
PDCD2 | BIOGRID; PUBMED:19146857; |
interacts with |
PAFAH1B2 | BIOGRID; PUBMED:16169070; |
interacts with |
PARK7 | BIOGRID; PUBMED:15525661; |
interacts with |
PARK7 | BIOGRID; PUBMED:17846173; |
interacts with |
TRIP13 | BIOGRID; PUBMED:16189514; |
interacts with |
STUB1 | BIOGRID; PUBMED:12150907; |
interacts with |
TUBB | HPRD; PUBMED:12716939; |
interacts with |
TUBA4A | HPRD; PUBMED:12716939; |
interacts with |
GRIN2B | HPRD; PUBMED:11679592; |
interacts with |
NDUFA4L2 | HPRD; PUBMED:16169070; |
interacts with |
CASP1 | HPRD; PUBMED:12692130; |
interacts with |
GPR37 | HPRD; PUBMED:12150907; |
interacts with |
HEXDC | HPRD; PUBMED:16169070; |
interacts with |
FBXW7 | HPRD; PUBMED:12628165; |
interacts with |
CASP8 | HPRD; PUBMED:12692130; |
interacts with |
CASK | HPRD; PUBMED:11679592; |
interacts with |
DLG1 | HPRD; PUBMED:16637659; |
interacts with |
RGS3 | HPRD; PUBMED:16637659; |
interacts with |
RAC1 | HPRD; PUBMED:16169070; |
interacts with |
RAD1 | HPRD; PUBMED:16169070; |
interacts with |
RANBP2 | HPRD; PUBMED:16332688; |
interacts with |
RGS2 | HPRD; PUBMED:16169070; |
interacts with |
YWHAH | HPRD; PUBMED:16096643; |
interacts with |
AIMP2 | HPRD; PUBMED:12783850; |
interacts with |
PSMA7 | HPRD; PUBMED:15987638; |
interacts with |
SNCA | HPRD; PUBMED:11588587; |
interacts with |
SYT11 | HPRD; PUBMED:12925569; |
interacts with |
UBE2L6 | HPRD; PUBMED:11078524; |
interacts with |
UBE2G1 | HPRD; PUBMED:11439185; |
interacts with |
UBE2L3 | HPRD; PUBMED:11078524; |
interacts with |
SIM2 | HPRD; PUBMED:15963499; |
interacts with |
SEPT4 | HPRD; PUBMED:14559152; |
interacts with |
SEPT5 | HPRD; PUBMED:11078524; |
interacts with |
PAFAH1B2 | HPRD; PUBMED:16169070; |
interacts with |
TRIP13 | HPRD; PUBMED:16189514; |
interacts with |
STUB1 | HPRD; PUBMED:12150907; |
interacts with |
ZNF746 | INTACT; PUBMED:21376232; |
interacts with |
TOMM20 | MINT; PUBMED:20153330; |
interacts with |
PINK1 | MINT; PUBMED:20153330; |
interacts with |
UBASH3A | MINT; PUBMED:17599067; |
interacts with |
UBASH3B | MINT; PUBMED:17599067; |
interacts with |
PDCD2 | MINT; PUBMED:19146857; |
Metabolic Interaction | | Top | |
There is no record for PARK2 |
Signaling Interaction | | Top | |
There is no record for PARK2 |
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