Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

857

Name

CAV1

Synonymous

BSCL3|CGL3|MSTP085|VIP21;caveolin 1, caveolae protein, 22kDa;CAV1;caveolin 1, caveolae protein, 22kDa

Definition

caveolin-1|cell growth-inhibiting protein 32

Position

7q31.1

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction

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Interaction Type

Interactor

Data Source

interacts with

 TRADDBIOGRID; PUBMED:11112773;

interacts with

 TRAF2BIOGRID; PUBMED:11112773;

interacts with

 TRAF2BIOGRID; PUBMED:11805080;

interacts with

 TGFBR1BIOGRID; PUBMED:11102446;

interacts with

 TNFRSF1ABIOGRID; PUBMED:12753742;

interacts with

 TNFBIOGRID; PUBMED:12753742;

interacts with

 TNFRSF1BBIOGRID; PUBMED:11112773;

interacts with

 NGFRBIOGRID; PUBMED:9867838;

interacts with

 SCP2BIOGRID; PUBMED:15182174;

interacts with

 NOS2BIOGRID; PUBMED:11114180;

interacts with

 NOS3BIOGRID; PUBMED:8910295;

interacts with

 Clic4BIOGRID; PUBMED:11563969;

interacts with

 BMXBIOGRID; PUBMED:11751885;

interacts with

 BTKBIOGRID; PUBMED:11751885;

interacts with

 ADRBK1BIOGRID; PUBMED:10085129;

interacts with

 ESR1BIOGRID; PUBMED:11563984;

interacts with

 EGFRBIOGRID; PUBMED:16407214;

interacts with

 EGFRBIOGRID; PUBMED:9374534;

interacts with

 GRK5BIOGRID; PUBMED:10085129;

interacts with

 FLOT2BIOGRID; PUBMED:10212252;

interacts with

 FLOT1BIOGRID; PUBMED:10212252;

interacts with

 EDNRBBIOGRID; PUBMED:12694195;

interacts with

 CAV2BIOGRID; PUBMED:12414992;

interacts with

 CAV2BIOGRID; PUBMED:9361015;

interacts with

 GJB2BIOGRID; PUBMED:11980479;

interacts with

 GJA1BIOGRID; PUBMED:11980479;

interacts with

 CSKBIOGRID; PUBMED:11805080;

interacts with

 GJB1BIOGRID; PUBMED:11980479;

interacts with

 DAG1BIOGRID; PUBMED:11724572;

interacts with

 PTPRFBIOGRID; PUBMED:12176037;

interacts with

 RCVRNBIOGRID; PUBMED:12507501;

interacts with

 GRK1BIOGRID; PUBMED:10085129;

interacts with

 PRKACABIOGRID; PUBMED:11546661;

interacts with

 APPBIOGRID; PUBMED:9553108;

interacts with

 ARBIOGRID; PUBMED:11278309;

interacts with

 AQP3BIOGRID; PUBMED:14675200;

interacts with

 INSRBIOGRID; PUBMED:10598578;

interacts with

 PDGFRABIOGRID; PUBMED:10066366;

interacts with

 PTPN6BIOGRID; PUBMED:12176037;

interacts with

 PTENBIOGRID; PUBMED:12176037;

interacts with

 PTGS2BIOGRID; PUBMED:11432874;

interacts with

 PLD2BIOGRID; PUBMED:10675563;

interacts with

 PLD2BIOGRID; PUBMED:14675200;

interacts with

 PDGFRBBIOGRID; PUBMED:10066366;

interacts with

 PTPN1BIOGRID; PUBMED:12176037;

interacts with

 PTPN11BIOGRID; PUBMED:12176037;

interacts with

 SRCBIOGRID; PUBMED:8910575;

interacts with

 SMAD2BIOGRID; PUBMED:11102446;

interacts with

 TRPC1BIOGRID; PUBMED:10980191;

interacts with

 TSC2BIOGRID; PUBMED:12147258;

interacts with

 S1PR1BIOGRID; PUBMED:10921915;

interacts with

 MAPK1CELL_MAP; PUBMED:12388423;

interacts with

 MAPK3CELL_MAP; PUBMED:12388423;

interacts with

 TRAF2CELL_MAP; PUBMED:11112773;

interacts with

 TNFRSF1BCELL_MAP; PUBMED:11112773;

interacts with

 EGFRCELL_MAP; PUBMED:10781609;

interacts with

 DNM1CELL_MAP; PUBMED:11956154;

interacts with

 GRB7CELL_MAP; PUBMED:11075810;

interacts with

 ARCELL_MAP; PUBMED:11278309;

interacts with

 MAPK1HPRD; PUBMED:12388423;

interacts with

 MMP14HPRD; PUBMED:15466865;

interacts with

 MAPK3HPRD; PUBMED:12388423;

interacts with

 MALLHPRD; PUBMED:1294831;

interacts with

 TRAF2HPRD; PUBMED:11112773;

interacts with

 TRAF6HPRD; PUBMED:14665433;

interacts with

 CD40HPRD; PUBMED:14665433;

interacts with

 TNFRSF1BHPRD; PUBMED:11112773;

interacts with

 NGFRHPRD; PUBMED:9867838;

interacts with

 SCP2HPRD; PUBMED:15182174;

interacts with

 NOS2HPRD; PUBMED:11114180;

interacts with

 NOS3HPRD; PUBMED:8910295;

interacts with

 LRP1HPRD; PUBMED:14593097;

interacts with

 BMXHPRD; PUBMED:11751885;

interacts with

 BST1HPRD; PUBMED:11866528;

interacts with

 BTKHPRD; PUBMED:11751885;

interacts with

 ADRBK1HPRD; PUBMED:10085129;

interacts with

 ESR1HPRD; PUBMED:11563984;

interacts with

 EGFRHPRD; PUBMED:9374534;

interacts with

 GP2HPRD; PUBMED:11039464;

interacts with

 DNM1HPRD; PUBMED:11956154;

interacts with

 GNAI2HPRD; PUBMED:8621645;

interacts with

 GRK5HPRD; PUBMED:10085129;

interacts with

 GRB7HPRD; PUBMED:11075810;

interacts with

 FLOT2HPRD; PUBMED:10212252;

interacts with

 FYNHPRD; PUBMED:12529448;

interacts with

 FLNAHPRD; PUBMED:10637311;

interacts with

 ERBB2HPRD; PUBMED:9685399;

interacts with

 EDNRBHPRD; PUBMED:12694195;

interacts with

 CAV2HPRD; PUBMED:12414992;

interacts with

 GJB2HPRD; PUBMED:11980479;

interacts with

 GJA1HPRD; PUBMED:11980479;

interacts with

 CSNK2A1HPRD; PUBMED:8058322;

interacts with

 CSKHPRD; PUBMED:11805080;

interacts with

 CSNK2A2HPRD; PUBMED:8058322;

interacts with

 GJA3HPRD; PUBMED:11980479;

interacts with

 IGF1RHPRD; PUBMED:18632619;

interacts with

 ILKHPRD; PUBMED:15722199;

interacts with

 IGFBP3HPRD; PUBMED:14576164;

interacts with

 HRASHPRD; PUBMED:8621645;

interacts with

 PTPRFHPRD; PUBMED:12176037;

interacts with

 RCVRNHPRD; PUBMED:12507501;

interacts with

 RAC1HPRD; PUBMED:15976327;

interacts with

 RHOAHPRD; PUBMED:9647788;

interacts with

 GRK1HPRD; PUBMED:10085129;

interacts with

 HTR1FHPRD; PUBMED:15190056;

interacts with

 AKAP1HPRD; PUBMED:11546661;

interacts with

 ARHPRD; PUBMED:11278309;

interacts with

 INSRHPRD; PUBMED:10598578;

interacts with

 PDGFRAHPRD; PUBMED:10066366;

interacts with

 PTPN6HPRD; PUBMED:12176037;

interacts with

 PTENHPRD; PUBMED:12176037;

interacts with

 PTGS2HPRD; PUBMED:11432874;

interacts with

 PLD2HPRD; PUBMED:10675563;

interacts with

 PRNPHPRD; PUBMED:10988071;

interacts with

 PTPN1HPRD; PUBMED:12176037;

interacts with

 PTPN11HPRD; PUBMED:12176037;

interacts with

 IRS1HPRD; PUBMED:15003536;

interacts with

 SRCHPRD; PUBMED:11039464;

interacts with

 SRCHPRD; PUBMED:8910575;

interacts with

 STOML3HPRD; PUBMED:12122055;

interacts with

 STRN4HPRD; PUBMED:11707266;

interacts with

 SOS1HPRD; PUBMED:15976327;

interacts with

 STRNHPRD; PUBMED:11707266;

interacts with

 YES1HPRD; PUBMED:11039464;

interacts with

 TRPC1HPRD; PUBMED:12732636;

interacts with

 KDRHPRD; PUBMED:12529448;

interacts with

 S1PR1HPRD; PUBMED:10921915;

interacts with

 TMED10INTACT; PUBMED:20427317;

interacts with

 FASINTACT; PUBMED:21382479;

interacts with

 TMED2INTACT; PUBMED:20427317;

interacts with

 BIDINTACT; PUBMED:21382479;

interacts with

 PROCRINTACT; PUBMED:20826780;

interacts with

 CD59INTACT; PUBMED:20427317;

interacts with

 F2RINTACT; PUBMED:20826780;

interacts with

 ABCB1MINT; PUBMED:15498565;

interacts with

 TRAF2MINT; PUBMED:11112773;

interacts with

 Grb7MINT; PUBMED:11075810;

interacts with

 EPS15L1MINT; DOI:10.1038/emboj.2009.46;

interacts with

 CSKMINT; PUBMED:16678999;

interacts with

 RASA1MINT; PUBMED:15504032;

interacts with

 HRASMINT; PUBMED:8621645;

interacts with

 PTPRFMINT; PUBMED:12176037;

interacts with

 PTPN6MINT; PUBMED:12176037;

interacts with

 PTENMINT; PUBMED:12176037;

interacts with

 PTPN1MINT; PUBMED:12176037;

interacts with

 PTPN1MINT; PUBMED:16388599;

interacts with

 PRKCDBPMINT; DOI:10.1038/emboj.2009.46;

interacts with

 PTPN11MINT; PUBMED:12176037;

interacts with

 SRCMINT; PUBMED:8621645;

interacts with

 TXNRD1MINT; PUBMED:19820694;

interacts with

 SDPRMINT; DOI:10.1038/emboj.2009.46;

interacts with

 SCARB2MINT; PUBMED:14570588;

Metabolic Interaction

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Interaction Type

Interactor

Data Source

metabolic catalysis

 TFDP1NCI_NATURE; PUBMED:10684646;

metabolic catalysis

 SP1NCI_NATURE; PUBMED:10684646;

metabolic catalysis

 TP53NCI_NATURE; PUBMED:10684646;

Signaling Interaction

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Interaction Type

Interactor

Data Source

reacts with

 CAV1IMID; PUBMED:10934248;

reacts with

 CAV1IMID; PUBMED:11883949;

reacts with

 STX1AIMID; PUBMED:11883949;

reacts with

 STX3IMID; PUBMED:11883949;

reacts with

 TGFBR2NCI_NATURE; PUBMED:10615055;PUBMED:9346908;PUBMED:11583628;PUBMED:9215638;PUBMED:12356868;PUBMED:15356634;PUBMED:9865696;PUBMED:9335507;PUBMED:10777621;PUBMED:9463378;PUBMED:12429842;PUBMED:9679059;PUBMED:12034739;PUBMED:11163210;PUBMED:12151385;PUBMED:11278251;PUBMED:12717440;

reacts with

 TGFBR2NCI_NATURE; PUBMED:18065769;

reacts with

 TGFBR1NCI_NATURE; PUBMED:10615055;PUBMED:9346908;PUBMED:11583628;PUBMED:9215638;PUBMED:12356868;PUBMED:15356634;PUBMED:9865696;PUBMED:9335507;PUBMED:10777621;PUBMED:9463378;PUBMED:12429842;PUBMED:9679059;PUBMED:12034739;PUBMED:11163210;PUBMED:12151385;PUBMED:11278251;PUBMED:12717440;

reacts with

 TGFBR1NCI_NATURE; PUBMED:18065769;

reacts with

 TGFB1NCI_NATURE; PUBMED:18065769;

reacts with

 NOS3NCI_NATURE; PUBMED:11425855;

state change

 CALM1NCI_NATURE; PUBMED:11425855;

state change

 EGFRNCI_NATURE; PUBMED:16388599;

reacts with

 HSP90AA1NCI_NATURE; PUBMED:11425855;

reacts with

 CAV1NCI_NATURE; PUBMED:10066366;

reacts with

 CAV1NCI_NATURE; PUBMED:10615055;PUBMED:9346908;PUBMED:11583628;PUBMED:9215638;PUBMED:12356868;PUBMED:15356634;PUBMED:9865696;PUBMED:9335507;PUBMED:10777621;PUBMED:9463378;PUBMED:12429842;PUBMED:9679059;PUBMED:12034739;PUBMED:11163210;PUBMED:12151385;PUBMED:11278251;PUBMED:12717440;

reacts with

 CAV1NCI_NATURE; PUBMED:11425855;

reacts with

 CAV1NCI_NATURE; PUBMED:18065769;

state change

 FKBP1ANCI_NATURE; PUBMED:10615055;PUBMED:9346908;PUBMED:11583628;PUBMED:9215638;PUBMED:12356868;PUBMED:15356634;PUBMED:9865696;PUBMED:9335507;PUBMED:10777621;PUBMED:9463378;PUBMED:12429842;PUBMED:9679059;PUBMED:12034739;PUBMED:11163210;PUBMED:12151385;PUBMED:11278251;PUBMED:12717440;

state change

 EGFNCI_NATURE; PUBMED:16388599;

state change

 INSNCI_NATURE; PUBMED:12036959;

reacts with

 ACVRL1NCI_NATURE; PUBMED:18065769;

state change

 INSRNCI_NATURE; PUBMED:12036959;

reacts with

 PDGFRANCI_NATURE; PUBMED:10066366;

state change

 PTPN1NCI_NATURE; PUBMED:16388599;PUBMED:12176037;

state change

 IRS1NCI_NATURE; PUBMED:12036959;

reacts with

 SMAD7NCI_NATURE; PUBMED:10615055;PUBMED:9346908;PUBMED:11583628;PUBMED:9215638;PUBMED:12356868;PUBMED:15356634;PUBMED:9865696;PUBMED:9335507;PUBMED:10777621;PUBMED:9463378;PUBMED:12429842;PUBMED:9679059;PUBMED:12034739;PUBMED:11163210;PUBMED:12151385;PUBMED:11278251;PUBMED:12717440;

reacts with

 ZFYVE9NCI_NATURE; PUBMED:10615055;PUBMED:9346908;PUBMED:11583628;PUBMED:9215638;PUBMED:12356868;PUBMED:15356634;PUBMED:9865696;PUBMED:9335507;PUBMED:10777621;PUBMED:9463378;PUBMED:12429842;PUBMED:9679059;PUBMED:12034739;PUBMED:11163210;PUBMED:12151385;PUBMED:11278251;PUBMED:12717440;

reacts with

 NOS3REACTOME; PUBMED:10781589;

reacts with

 NOS3REACTOME; PUBMED:12482742;PUBMED:11988487;PUBMED:9580552;

reacts with

 NOS3REACTOME; PUBMED:16722822;PUBMED:16234328;

reacts with

 NOS3REACTOME; PUBMED:16722822;PUBMED:16807357;PUBMED:16234328;

reacts with

 NOS3REACTOME; PUBMED:16807357;

reacts with

 NOS3REACTOME; PUBMED:16807357;PUBMED:12446846;

reacts with

 NOS3REACTOME; PUBMED:9188442;PUBMED:12842859;

reacts with

 NOS3REACTOME; PUBMED:9712842;PUBMED:8798458;PUBMED:9325253;PUBMED:11498544;

reacts with

 NOSTRINREACTOME; PUBMED:16722822;PUBMED:16234328;

reacts with

 NOSTRINREACTOME; PUBMED:16722822;PUBMED:16807357;PUBMED:16234328;

reacts with

 NOSTRINREACTOME; PUBMED:16807357;

reacts with

 NOSTRINREACTOME; PUBMED:16807357;PUBMED:12446846;

reacts with

 CALM1REACTOME; PUBMED:10781589;

reacts with

 CALM1REACTOME; PUBMED:12482742;PUBMED:11988487;PUBMED:9580552;

reacts with

 CALM1REACTOME; PUBMED:9188442;PUBMED:12842859;

reacts with

 BSGREACTOME; PUBMED:14707126;PUBMED:15201341;

reacts with

 HSP90AA1REACTOME; PUBMED:10781589;

reacts with

 HSP90AA1REACTOME; PUBMED:12482742;PUBMED:11988487;PUBMED:9580552;

reacts with

 CAV1REACTOME; PUBMED:10781589;

reacts with

 CAV1REACTOME; PUBMED:12482742;PUBMED:11988487;PUBMED:9580552;

reacts with

 CAV1REACTOME; PUBMED:14707126;PUBMED:15201341;

reacts with

 CAV1REACTOME; PUBMED:16722822;PUBMED:16234328;

reacts with

 CAV1REACTOME; PUBMED:16722822;PUBMED:16807357;PUBMED:16234328;

reacts with

 CAV1REACTOME; PUBMED:16807357;

reacts with

 CAV1REACTOME; PUBMED:16807357;PUBMED:12446846;

reacts with

 CAV1REACTOME; PUBMED:9188442;PUBMED:12842859;

reacts with

 CAV1REACTOME; PUBMED:9712842;PUBMED:8798458;PUBMED:9325253;PUBMED:11498544;

reacts with

 WASLREACTOME; PUBMED:16722822;PUBMED:16807357;PUBMED:16234328;

reacts with

 WASLREACTOME; PUBMED:16807357;

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