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General information | Expression | Regulation | Mutation | Interaction |
Basic Information |
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Gene ID | 8795 |
Name | TNFRSF10B |
Synonymous | CD262|DR5|KILLER|KILLER/DR5|TRAIL-R2|TRAILR2|TRICK2|TRICK2A|TRICK2B|TRICKB|ZTNFR9;tumor necrosis factor receptor superfamily, member 10b;TNFRSF10B;tumor necrosis factor receptor superfamily, member 10b |
Definition | Fas-like protein|TNF-related apoptosis-inducing ligand receptor 2|apoptosis inducing protein TRICK2A/2B|apoptosis inducing receptor TRAIL-R2|cytotoxic TRAIL receptor-2|death domain containing receptor for TRAIL/Apo-2L|death receptor 5|p53-regulated DNA da |
Position | 8p22-p21 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
Interaction Type |
Interactor |
Data Source |
---|---|---|
interacts with |
MAPK8 | BIOGRID; PUBMED:15659383; |
interacts with |
MSN | BIOGRID; PUBMED:15659383; |
interacts with |
TRADD | BIOGRID; PUBMED:9430227; |
interacts with |
TNFSF10 | BIOGRID; PUBMED:10549288; |
interacts with |
TNFSF10 | BIOGRID; PUBMED:11094155; |
interacts with |
TNFSF10 | BIOGRID; PUBMED:9311998; |
interacts with |
TIMM50 | BIOGRID; PUBMED:15044455; |
interacts with |
FASLG | BIOGRID; PUBMED:15659383; |
interacts with |
TNFRSF1A | BIOGRID; PUBMED:15659383; |
interacts with |
FAS | BIOGRID; PUBMED:15659383; |
interacts with |
CFLAR | BIOGRID; PUBMED:11940602; |
interacts with |
CFLAR | BIOGRID; PUBMED:9325248; |
interacts with |
BID | BIOGRID; PUBMED:15659383; |
interacts with |
EZR | BIOGRID; PUBMED:15659383; |
interacts with |
FADD | BIOGRID; PUBMED:11940602; |
interacts with |
FADD | BIOGRID; PUBMED:15659383; |
interacts with |
FADD | BIOGRID; PUBMED:9430227; |
interacts with |
ARHGDIA | BIOGRID; PUBMED:15659383; |
interacts with |
CASP8 | BIOGRID; PUBMED:11940602; |
interacts with |
CASP8 | BIOGRID; PUBMED:15659383; |
interacts with |
CASP8 | BIOGRID; PUBMED:9325248; |
interacts with |
CASP10 | BIOGRID; PUBMED:15659383; |
interacts with |
CASP10 | BIOGRID; PUBMED:9325248; |
interacts with |
CBL | BIOGRID; PUBMED:19932172; |
interacts with |
RIPK1 | BIOGRID; PUBMED:9430227; |
interacts with |
RHOA | BIOGRID; PUBMED:15659383; |
interacts with |
MADD | HPRD; PUBMED:15208670; |
interacts with |
TRADD | HPRD; PUBMED:9430227; |
interacts with |
TNFRSF10A | HPRD; PUBMED:10894160; |
interacts with |
TNFRSF10A | HPRD; PUBMED:9430228; |
interacts with |
TNFSF10 | HPRD; PUBMED:9311998; |
interacts with |
TNFRSF10D | HPRD; PUBMED:16319225; |
interacts with |
CFLAR | HPRD; PUBMED:11193041; |
interacts with |
CFLAR | HPRD; PUBMED:9325248; |
interacts with |
FADD | HPRD; PUBMED:10894160; |
interacts with |
FADD | HPRD; PUBMED:9430227; |
interacts with |
CASP8 | HPRD; PUBMED:10894160; |
interacts with |
CASP8 | HPRD; PUBMED:12218097; |
interacts with |
CASP8 | HPRD; PUBMED:9325248; |
interacts with |
CASP10 | HPRD; PUBMED:9325248; |
interacts with |
RIPK1 | HPRD; PUBMED:9430227; |
interacts with |
TNFSF10 | MINT; PUBMED:10542098; |
interacts with |
FADD | MINT; PUBMED:10894160; |
Metabolic Interaction | | Top | |
Interaction Type |
Interactor |
Data Source |
---|---|---|
metabolic catalysis |
TP53 | NCI_NATURE; PUBMED:10777207;PUBMED:15289308; |
Signaling Interaction | | Top | |
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
TRADD | NCI_NATURE; PUBMED:10958661;PUBMED:10521444; |
reacts with |
TRADD | NCI_NATURE; PUBMED:16940186;PUBMED:9430227; |
reacts with |
TNFSF10 | NCI_NATURE; PUBMED:10894160;PUBMED:10894161;PUBMED:10783243; |
reacts with |
TNFSF10 | NCI_NATURE; PUBMED:10958661;PUBMED:10521444; |
reacts with |
TNFSF10 | NCI_NATURE; PUBMED:16940186;PUBMED:9430227; |
reacts with |
TNFSF10 | NCI_NATURE; PUBMED:9311998;PUBMED:9242610; |
reacts with |
TRAF2 | NCI_NATURE; PUBMED:10958661;PUBMED:10521444; |
reacts with |
TNFRSF10B | NCI_NATURE; PUBMED:10894160;PUBMED:10894161;PUBMED:10783243; |
reacts with |
TNFRSF10B | NCI_NATURE; PUBMED:10958661;PUBMED:10521444; |
reacts with |
TNFRSF10B | NCI_NATURE; PUBMED:16940186;PUBMED:9430227; |
reacts with |
TNFRSF10B | NCI_NATURE; PUBMED:9311998;PUBMED:9242610; |
reacts with |
FADD | NCI_NATURE; PUBMED:10894160;PUBMED:10894161;PUBMED:10783243; |
reacts with |
FADD | NCI_NATURE; PUBMED:10958661;PUBMED:10521444; |
reacts with |
FADD | NCI_NATURE; PUBMED:16940186;PUBMED:9430227; |
reacts with |
RIPK1 | NCI_NATURE; PUBMED:10958661;PUBMED:10521444; |
reacts with |
RIPK1 | NCI_NATURE; PUBMED:16940186;PUBMED:9430227; |
reacts with |
TNFSF10 | REACTOME; PUBMED:10894160; |
reacts with |
TNFSF10 | REACTOME; PUBMED:11717445;PUBMED:12198154; |
reacts with |
TNFSF10 | REACTOME; PUBMED:8777713; |
reacts with |
TNFRSF10B | REACTOME; PUBMED:10894160; |
reacts with |
TNFRSF10B | REACTOME; PUBMED:11717445;PUBMED:12198154; |
reacts with |
TNFRSF10B | REACTOME; PUBMED:8777713; |
state change |
CFLAR | REACTOME; PUBMED:10894160; |
reacts with |
FADD | REACTOME; PUBMED:10894160; |
reacts with |
FADD | REACTOME; PUBMED:11717445;PUBMED:12198154; |
reacts with |
CASP8 | REACTOME; PUBMED:10894160; |
reacts with |
CASP10 | REACTOME; PUBMED:11717445;PUBMED:12198154; |
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