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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 8795 |
Name | TNFRSF10B |
Synonymous | CD262|DR5|KILLER|KILLER/DR5|TRAIL-R2|TRAILR2|TRICK2|TRICK2A|TRICK2B|TRICKB|ZTNFR9;tumor necrosis factor receptor superfamily, member 10b;TNFRSF10B;tumor necrosis factor receptor superfamily, member 10b |
Definition | Fas-like protein|TNF-related apoptosis-inducing ligand receptor 2|apoptosis inducing protein TRICK2A/2B|apoptosis inducing receptor TRAIL-R2|cytotoxic TRAIL receptor-2|death domain containing receptor for TRAIL/Apo-2L|death receptor 5|p53-regulated DNA da |
Position | 8p22-p21 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
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Regulation From TransFac database |
3 Apo2L(h) + 3 DR5(h) <==> (Apo2L(h):DR5(h))3 (binding) | DR5(h) + FADD(h) <==> DR5(h):FADD(h) (binding) | DR5(h) + Caspase-8-p43(h) <==> DR5(h):Caspase-8-p43(h) (binding) | Apo2L(h) + DR5(h) <==> Apo2L(h):DR5(h) (binding) | Apo2L(m) + DR5(h) <==> Apo2L(m):DR5(h) (binding) | proCaspase-8(h) + Apo2L(h) + FADD(h) + DR5(h) <==> proCaspase-8(h):Apo2L(h):FADD(h):DR5(h) (binding) | proCaspase-10(h) + Apo2L(h) + FADD(h) + DR5(h) <==> proCaspase-10(h):Apo2L(h):FADD(h):DR5(h) (binding) | proCaspase-10(h) + DR5(h) + FADD(h) <==> proCaspase-10(h):DR5(h):FADD(h) (binding) | TRADD(h) + DR5(h) <==> TRADD(h):DR5(h) (binding) | c-FLIP-L(h) + DR5(h) <==> c-FLIP-L(h):DR5(h) (binding) | c-FLIP-L(m.s.) + DR5(h) <==> c-FLIP-L(m.s.):DR5(h) (binding) | DR5(h) + c-FLIP-L-p12(m.s.) <==> c-FLIP-L-p12(m.s.):DR5(h) (binding) | Apo2L(h) + DR5(h) + FADD(h) + proCaspase-8(h) + c-FLIP-L(h) <==> Apo2L(h):DR5(h):FADD(h):proCaspase-8(h):c-FLIP-L(h) (binding) | DR4(h) + DR5(h) + Caspase-8-p26(h) + FADD(h) + RIP(h) + c-FLIP-L-p43(h) + c-FLIP-S(h) <==> DR4(h):DR5(h):Caspase-8-p26(h):FADD(h):RIP(h):c-FLIP-L-p43(h):c-FLIP-S(h) (binding) | TNFRSF10B(h) --> DR5(h) (expression). | ehf(h) --> DR5(h) (increase of abundance) | slc5a3(h) --/ DR5(h) (decrease of abundance) | IFNgamma(m.s.) --/ DR5(h) (decrease of abundance) | TNFRSF10B(h) --> DR5-L(h) (expression). | TNFRSF10B(h) --> DR5-S(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
There is no record for TNFRSF10B |
Methylation Profile From DiseaseMeth database | | Top | |
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Chromosome |
Location |
Source |
|---|---|---|
chr8 |
Promoter: 22982137 - 22984137 | Agilent_014791 |
chr8 |
Promoter: 22982137 - 22984137 | GoldenGate_Methylation_Cancer_Panel_I |
chr8 |
Promoter: 22982137 - 22984137 | GoldenGate_Methylation_Cancer_Panel_I |
chr8 |
Promoter: 22982137 - 22984137 | GSE27584 |
chr8 |
Promoter: 22982137 - 22984137 | GSE27584 |
chr8 |
Promoter: 22982137 - 22984137 | Agilent_014791 |
chr8 |
Promoter: 22982137 - 22984137 | PMID:15788647 |
chr8 |
Promoter: 22982137 - 22984137 | PMID:15788647 |