Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

9978

Name

RBX1

Synonymous

BA554C12.1|RNF75|ROC1;ring-box 1, E3 ubiquitin protein ligase;RBX1;ring-box 1, E3 ubiquitin protein ligase

Definition

E3 ubiquitin-protein ligase RBX1|RING box protein 1|RING finger protein 75|RING-box protein 1|ZYP protein|regulator of cullins 1

Position

22q13.2

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction

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Interaction Type

Interactor

Data Source

interacts with

 NCOA3BIOGRID; PUBMED:21577200;

interacts with

 ZC3HC1BIOGRID; PUBMED:16009132;

interacts with

 NEDD8BIOGRID; PUBMED:12481031;

interacts with

 Rps6kb1BIOGRID; PUBMED:18279656;

interacts with

 RPS6KB1BIOGRID; PUBMED:18279656;

interacts with

 KEAP1BIOGRID; PUBMED:15983046;

interacts with

 KEAP1BIOGRID; PUBMED:20027226;

interacts with

 ARID1BBIOGRID; PUBMED:20086098;

interacts with

 TCEB2BIOGRID; PUBMED:12048197;

interacts with

 CAND1BIOGRID; PUBMED:12609982;

interacts with

 CAND1BIOGRID; PUBMED:18826954;

interacts with

 HSPA8BIOGRID; PUBMED:12481031;

interacts with

 FBXO18BIOGRID; PUBMED:11956208;

interacts with

 FBXO18BIOGRID; PUBMED:15118074;

interacts with

 FBXW8BIOGRID; PUBMED:12481031;

interacts with

 FBXW8BIOGRID; PUBMED:17205132;

interacts with

 FBXO31BIOGRID; PUBMED:16357137;

interacts with

 FBXO11BIOGRID; PUBMED:17098746;

interacts with

 GANBIOGRID; PUBMED:15983046;

interacts with

 FBXW11BIOGRID; PUBMED:10230406;

interacts with

 FBXO22BIOGRID; PUBMED:12481031;

interacts with

 FBXO3BIOGRID; PUBMED:12481031;

interacts with

 ENC1BIOGRID; PUBMED:15983046;

interacts with

 E2F1BIOGRID; PUBMED:11245432;

interacts with

 CASP3BIOGRID; PUBMED:17217622;

interacts with

 CCND3BIOGRID; PUBMED:11311237;

interacts with

 CCND2BIOGRID; PUBMED:11311237;

interacts with

 CUL1BIOGRID; PUBMED:10230406;

interacts with

 CUL1BIOGRID; PUBMED:10230407;

interacts with

 CUL1BIOGRID; PUBMED:10648623;

interacts with

 CUL1BIOGRID; PUBMED:10713156;

interacts with

 CUL1BIOGRID; PUBMED:10748083;

interacts with

 CUL1BIOGRID; PUBMED:11245432;

interacts with

 CUL1BIOGRID; PUBMED:11483504;

interacts with

 CUL1BIOGRID; PUBMED:11861641;

interacts with

 CUL1BIOGRID; PUBMED:11956208;

interacts with

 CUL1BIOGRID; PUBMED:11961546;

interacts with

 CUL1BIOGRID; PUBMED:12481031;

interacts with

 CUL1BIOGRID; PUBMED:12609982;

interacts with

 CUL1BIOGRID; PUBMED:12706828;

interacts with

 CUL1BIOGRID; PUBMED:15448697;

interacts with

 CUL1BIOGRID; PUBMED:16123592;

interacts with

 CUL1BIOGRID; PUBMED:16759355;

interacts with

 CUL1BIOGRID; PUBMED:18826954;

interacts with

 CUL5BIOGRID; PUBMED:10230407;

interacts with

 CUL5BIOGRID; PUBMED:11861641;

interacts with

 CUL5BIOGRID; PUBMED:18805092;

interacts with

 DCUN1D1BIOGRID; PUBMED:18826954;

interacts with

 DDB2BIOGRID; PUBMED:16473935;

interacts with

 CUL2BIOGRID; PUBMED:10230407;

interacts with

 CUL2BIOGRID; PUBMED:11861641;

interacts with

 CUL2BIOGRID; PUBMED:12481031;

interacts with

 CUL2BIOGRID; PUBMED:15448697;

interacts with

 CUL2BIOGRID; PUBMED:17132228;

interacts with

 CUL2BIOGRID; PUBMED:17183367;

interacts with

 CUL2BIOGRID; PUBMED:21778237;

interacts with

 CUL4BBIOGRID; PUBMED:12481031;

interacts with

 CUL4ABIOGRID; PUBMED:10230407;

interacts with

 CUL4ABIOGRID; PUBMED:11861641;

interacts with

 CUL4ABIOGRID; PUBMED:12481031;

interacts with

 CUL4ABIOGRID; PUBMED:15448697;

interacts with

 CUL4ABIOGRID; PUBMED:18593899;

interacts with

 CUL3BIOGRID; PUBMED:11861641;

interacts with

 CUL3BIOGRID; PUBMED:12481031;

interacts with

 CUL3BIOGRID; PUBMED:15448697;

interacts with

 CUL3BIOGRID; PUBMED:15601839;

interacts with

 CUL3BIOGRID; PUBMED:20027226;

interacts with

 CUL7BIOGRID; PUBMED:12481031;

interacts with

 CUL7BIOGRID; PUBMED:16142236;

interacts with

 CUL7BIOGRID; PUBMED:16547496;

interacts with

 DET1BIOGRID; PUBMED:14739464;

interacts with

 DDB1BIOGRID; PUBMED:15448697;

interacts with

 DDB1BIOGRID; PUBMED:16473935;

interacts with

 DDB1BIOGRID; PUBMED:16678110;

interacts with

 KBTBD10BIOGRID; PUBMED:15983046;

interacts with

 DIO2BIOGRID; PUBMED:15965468;

interacts with

 RFWD2BIOGRID; PUBMED:14739464;

interacts with

 ABTB2BIOGRID; PUBMED:18429817;

interacts with

 ACTG1BIOGRID; PUBMED:12481031;

interacts with

 PGAM5BIOGRID; PUBMED:17046835;

interacts with

 PSMA6BIOGRID; PUBMED:16759355;

interacts with

 PTGS2BIOGRID; PUBMED:17429597;

interacts with

 SKP2BIOGRID; PUBMED:11245432;

interacts with

 SKP2BIOGRID; PUBMED:18826954;

interacts with

 SKP1BIOGRID; PUBMED:11245432;

interacts with

 SKP1BIOGRID; PUBMED:12628165;

interacts with

 SKP1BIOGRID; PUBMED:15452136;

interacts with

 SKP1BIOGRID; PUBMED:16357137;

interacts with

 VHLBIOGRID; PUBMED:12048197;

interacts with

 VHLBIOGRID; PUBMED:12604794;

interacts with

 VHLBIOGRID; PUBMED:16325183;

interacts with

 VHLBIOGRID; PUBMED:17353931;

interacts with

 CDC34BIOGRID; PUBMED:10748083;

interacts with

 CDC34BIOGRID; PUBMED:11675391;

interacts with

 CDC34BIOGRID; PUBMED:16123592;

interacts with

 CCND1BIOGRID; PUBMED:11311237;

interacts with

 MED8HPRD; PUBMED:12149480;

interacts with

 TBL3HPRD; PUBMED:17392787;

interacts with

 NEDD8HPRD; PUBMED:10713156;

interacts with

 NEURL2HPRD; PUBMED:14960280;

interacts with

 LRRC41HPRD; PUBMED:11384984;

interacts with

 TCEB2HPRD; PUBMED:11384984;

interacts with

 TCEB2HPRD; PUBMED:12149480;

interacts with

 TCEB2HPRD; PUBMED:14960280;

interacts with

 TCEB2HPRD; PUBMED:16503656;

interacts with

 CAND1HPRD; PUBMED:12609982;

interacts with

 TCEB1HPRD; PUBMED:11384984;

interacts with

 TCEB1HPRD; PUBMED:12149480;

interacts with

 TCEB1HPRD; PUBMED:14960280;

interacts with

 TCEB1HPRD; PUBMED:16503656;

interacts with

 FBXO2HPRD; PUBMED:12140560;

interacts with

 FBXO18HPRD; PUBMED:11956208;

interacts with

 FBXO33HPRD; PUBMED:16797541;

interacts with

 FBXW8HPRD; PUBMED:12481031;

interacts with

 FBXO11HPRD; PUBMED:17098746;

interacts with

 TCEB3HPRD; PUBMED:11384984;

interacts with

 GPS1HPRD; PUBMED:11337588;

interacts with

 CUL1HPRD; PUBMED:10713156;

interacts with

 CUL1HPRD; PUBMED:11359933;

interacts with

 CUL1HPRD; PUBMED:11675391;

interacts with

 CUL1HPRD; PUBMED:11717410;

interacts with

 CUL1HPRD; PUBMED:11961546;

interacts with

 CUL1HPRD; PUBMED:12140560;

interacts with

 CUL1HPRD; PUBMED:16797541;

interacts with

 CUL1HPRD; PUBMED:17098746;

interacts with

 CUL5HPRD; PUBMED:11384984;

interacts with

 CUL5HPRD; PUBMED:14564014;

interacts with

 CUL5HPRD; PUBMED:14960280;

interacts with

 CUL2HPRD; PUBMED:12149480;

interacts with

 CUL2HPRD; PUBMED:16325183;

interacts with

 CUL2HPRD; PUBMED:16503656;

interacts with

 CUL4BHPRD; PUBMED:12609982;

interacts with

 CUL4BHPRD; PUBMED:17392787;

interacts with

 COPS6HPRD; PUBMED:11337588;

interacts with

 CUL4AHPRD; PUBMED:14739464;

interacts with

 CUL4AHPRD; PUBMED:18593899;

interacts with

 CUL3HPRD; PUBMED:11311237;

interacts with

 CUL3HPRD; PUBMED:18429817;

interacts with

 CUL7HPRD; PUBMED:10531037;

interacts with

 CUL7HPRD; PUBMED:12481031;

interacts with

 DDB1HPRD; PUBMED:17392787;

interacts with

 ABTB2HPRD; PUBMED:18429817;

interacts with

 AHRHPRD; PUBMED:17392787;

interacts with

 SKP1HPRD; PUBMED:10713156;

interacts with

 SKP1HPRD; PUBMED:11359933;

interacts with

 SKP1HPRD; PUBMED:11717410;

interacts with

 SKP1HPRD; PUBMED:12140560;

interacts with

 SKP1HPRD; PUBMED:12481031;

interacts with

 SKP1HPRD; PUBMED:16797541;

interacts with

 SKP1HPRD; PUBMED:17098746;

interacts with

 SOCS1HPRD; PUBMED:11384984;

interacts with

 WSB1HPRD; PUBMED:11384984;

interacts with

 VHLHPRD; PUBMED:11384984;

interacts with

 VHLHPRD; PUBMED:15601820;

interacts with

 VHLHPRD; PUBMED:16325183;

interacts with

 VHLHPRD; PUBMED:16503656;

interacts with

 CDC34HPRD; PUBMED:10713156;

interacts with

 CDC34HPRD; PUBMED:11675391;

interacts with

 CCND1HPRD; PUBMED:11311237;

interacts with

 RELAMINT; PUBMED:19327355;

interacts with

 TCEB2MINT; PUBMED:19327355;

interacts with

 TCEB1MINT; PUBMED:19327355;

interacts with

 FBXO33MINT; PUBMED:16797541;

interacts with

 FBXL12MINT; PUBMED:18660753;

interacts with

 CUL1MINT; PUBMED:11961546;

interacts with

 CUL1MINT; PUBMED:18239684;

interacts with

 CUL1MINT; PUBMED:18660753;

interacts with

 CUL2MINT; PUBMED:17183367;

interacts with

 CUL2MINT; PUBMED:19327355;

interacts with

 SKP2MINT; PUBMED:18239684;

interacts with

 SKP1MINT; PUBMED:11961546;

interacts with

 SKP1MINT; PUBMED:18239684;

interacts with

 SKP1MINT; PUBMED:18660753;

interacts with

 SOCS1MINT; PUBMED:19327355;

interacts with

 CKS1BMINT; PUBMED:18239684;

Metabolic Interaction

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There is no record for RBX1

Signaling Interaction

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Interaction Type

Interactor

Data Source

reacts with

 BTRCCELL_MAP; PUBMED:11359933;

reacts with

 CUL1CELL_MAP; PUBMED:11359933;

reacts with

 RBX1CELL_MAP; PUBMED:11359933;

reacts with

 SKP1CELL_MAP; PUBMED:11359933;

reacts with

 TCEB2NCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

reacts with

 HIF1ANCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

reacts with

 TCEB1NCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

reacts with

 CUL2NCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

reacts with

 RBX1NCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

reacts with

 VHLNCI_NATURE; PUBMED:11598268;PUBMED:11292862;PUBMED:11292861;PUBMED:10878807;PUBMED:10973499;PUBMED:11595184;PUBMED:12464182;PUBMED:10353251;

reacts with

 NFKB1REACTOME; PUBMED:14673179;

reacts with

 NFKB1REACTOME; PUBMED:14673179;PUBMED:12482991;

reacts with

 TCEB2REACTOME; PUBMED:14564014;PUBMED:15574592;PUBMED:16530799;

reacts with

 TCEB2REACTOME; PUBMED:15781449;

reacts with

 TCEB2REACTOME; PUBMED:15781449;PUBMED:14528300;PUBMED:14564014;

state change

 TCEB2REACTOME; PUBMED:15781449;

reacts with

 TCEB1REACTOME; PUBMED:14564014;PUBMED:15574592;PUBMED:16530799;

reacts with

 TCEB1REACTOME; PUBMED:15781449;

reacts with

 TCEB1REACTOME; PUBMED:15781449;PUBMED:14528300;PUBMED:14564014;

state change

 TCEB1REACTOME; PUBMED:15781449;

reacts with

 BTRCREACTOME; PUBMED:14673179;

reacts with

 BTRCREACTOME; PUBMED:14673179;PUBMED:12482991;

state change

 BTRCREACTOME; PUBMED:14673179;

reacts with

 CUL1REACTOME; PUBMED:14673179;

reacts with

 CUL1REACTOME; PUBMED:14673179;PUBMED:12482991;

state change

 CUL1REACTOME; PUBMED:14673179;

reacts with

 CUL5REACTOME; PUBMED:14564014;PUBMED:15574592;PUBMED:16530799;

reacts with

 CUL5REACTOME; PUBMED:15781449;

reacts with

 CUL5REACTOME; PUBMED:15781449;PUBMED:14528300;PUBMED:14564014;

state change

 CUL5REACTOME; PUBMED:15781449;

reacts with

 RBX1REACTOME; PUBMED:14564014;PUBMED:15574592;PUBMED:16530799;

reacts with

 RBX1REACTOME; PUBMED:14673179;

reacts with

 RBX1REACTOME; PUBMED:14673179;PUBMED:12482991;

reacts with

 RBX1REACTOME; PUBMED:15781449;

reacts with

 RBX1REACTOME; PUBMED:15781449;PUBMED:14528300;PUBMED:14564014;

state change

 RBX1REACTOME; PUBMED:14673179;

state change

 RBX1REACTOME; PUBMED:15781449;

reacts with

 SKP1REACTOME; PUBMED:14673179;

reacts with

 SKP1REACTOME; PUBMED:14673179;PUBMED:12482991;

state change

 SKP1REACTOME; PUBMED:14673179;

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