Basic Information
Gene ID	9978
Name	RBX1
Synonymous	BA554C12.1\|RNF75\|ROC1;ring-box 1, E3 ubiquitin protein ligase;RBX1;ring-box 1, E3 ubiquitin protein ligase
Definition	E3 ubiquitin-protein ligase RBX1\|RING box protein 1\|RING finger protein 75\|RING-box protein 1\|ZYP protein\|regulator of cullins 1
Position	22q13.2
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database
Cul-1(h) + Roc1(h) <==> Roc1(h):Cul-1(h) (binding)
Cul-1(h) + HOS(h) + Roc1(h) + Skp1(h) <==> Cul-1(h):HOS(h):Roc1(h):Skp1(h) (binding)
Cul-1(h) + Roc1(h) + Skp1(h) <==> Cul-1(h):Roc1(h):Skp1(h) (binding)
COP1(h) + Roc1(h) <==> COP1(h):Roc1(h) (binding)
Roc1(h) --> PARP-p89(h) (increase of cleavage)
Roc1(h) + PSMA6(h) <==> Roc1(h):PSMA6(h) (binding)
Roc1(h) + Cul-1(m.s.) <==> Roc1(h):Cul-1(m.s.) (binding)
Roc1(h) + Fbx33(m) <==> Roc1(h):Fbx33(m) (binding)
Roc1(h) + Cul-1(h) + Skp1(h) + Fbx11-isoform1(h) <==> Roc1(h):Cul-1(h):Skp1(h):Fbx11-isoform1(h) (binding)
VHL(h) + Roc1(h) <==> VHL(h):Roc1(h) (binding)
Roc1(h) + CUL4A(h) + DDB-2(h) + DDB1(h) <==> Roc1(h):CUL4A(h):DDB-2(h):DDB1(h) (binding)
RBX1(h) --> Roc1(h) (expression).
c-Jun(h) + n ubiquitin(v.s.) --E1(rb),Ubc5C(h),DET1(h),DDB1(h),CUL4A(m),Roc1(h),COP1(h),ATP--> c-Jun(h){ub(n)} (ubiquitination)
cyclinD1a(h) + Roc1(h) <==> cyclinD1a(h):Roc1(h) (binding)
cyclinD2(h) + Roc1(h) <==> cyclinD2(h):Roc1(h) (binding)
cyclinD3(h) + Roc1(h) <==> cyclinD3(h):Roc1(h) (binding)
RBX1(h) --> Roc1(h) (expression).
Daxx(h) + ubiquitin(h) --Roc1(h),CUL3(h){nedd}:SPOP(h)--> Daxx(h){ub} (ubiquitination)

There is no record for RBX1