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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 55294 |
Name | FBXW7 |
Synonymous | AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10;F-box and WD repeat domain containing 7;FBXW7;F-box and WD repeat domain containing 7 |
Definition | F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)|F-box protein FBW7|F-box protein FBX30|F-box protein SEL-10|F-box/WD repeat-containing protein 7|hAgo|hCdc4|homolog of C elegans sel-10 |
Position | 4q31.3 |
Gene Type | protein-coding |
Gene Mutation: | Substitution Insertion & Deletion Other Mutation |
Substitution | | Top | |
There is no record for FBXW7 |
Indel | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Deletion - Frameshift; c.556_559delAAAC; |
n; upper_aerodigestive_tract; mouth | squamous_cell_carcinoma; carcinoma |
Deletion - Frameshift; c.540delT; 4:153490688-153490688 |
prostate | carcinoma |
Deletion - Frameshift; c.1996delG; 4:153463611-153463611 |
stomach | adenocarcinoma; carcinoma |
Deletion - Frameshift; c.2001delG; 4:153463606-153463606 |
large_intestine; colon | adenocarcinoma; carcinoma |
Deletion - In frame; c.349_351delGAG; 4:153552055-153552057 |
bone | osteosarcoma |
Deletion - Frameshift; c.1417delA; 4:153468811-153468811 |
ovary | adenocarcinoma; carcinoma |
Deletion - Frameshift; c.1417delA; 4:153468811-153468811 |
NS | malignant_melanoma |
Deletion - Frameshift; c.1958delC; 4:153463649-153463649 |
haematopoietic_and_lymphoid_ti; lymph_node | lymphoid_neoplasm |
Deletion - In frame; c.349_351delGAG; 4:153552055-153552057 |
kidney | clear_cell_renal_cell_carcinoma; carcinoma |
Other Mutation | | Top | |
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
Complex - deletion inframe; c.1736_1741delGGCACC; 4:153464900-153464905 |
large_intestine; colon | adenocarcinoma; carcinoma |