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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 999 |
Name | CDH1 |
Synonymous | Arc-1|CD324|CDHE|ECAD|LCAM|UVO;cadherin 1, type 1, E-cadherin (epithelial);CDH1;cadherin 1, type 1, E-cadherin (epithelial) |
Definition | CAM 120/80|E-Cadherin|cadherin 1, E-cadherin (epithelial)|cadherin-1|calcium-dependent adhesion protein, epithelial|cell-CAM 120/80|epithelial cadherin|uvomorulin |
Position | 16q22.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
|
Regulation From TransFac database |
E-cadherin(h) + IQGAP1(h) <==> E-cadherin(h):IQGAP1(h) (binding) | alpha-catenin1(h) + beta-catenin(h) + E-cadherin(h) + p120CAS(h) + plakoglobin(h) <==> alpha-catenin1(h):beta-catenin(h):E-cadherin(h):plakoglobin(h):p120CAS(h) (binding) | beta-catenin(h) + E-cadherin(h) <==> beta-catenin(h):E-cadherin(h) (binding) | alpha-catenin1(h) + beta-catenin(h){pY} + E-cadherin(h) + LAR(h) + plakoglobin(h){pY} <==> alpha-catenin1(h):beta-catenin(h){pY}:E-cadherin(h):plakoglobin(h){pY}:LAR(h) (binding) | E-cadherin(h) --gamma-secretase(h)--> E-cadherin-CTF2(h) + E-cadherin-NTF2(h) (processing) | E-cadherin(h) + cortactin(ha) <==> cortactin(ha):E-cadherin(h) (binding) | Arp3(h) + E-cadherin(h) <==> Arp3(h):E-cadherin(h) (binding) | p34arc(ha) + E-cadherin(h) <==> E-cadherin(h):p34arc(ha) (binding) | Arp3(h) + p34arc(ha) + E-cadherin(h) <==> Arp3(h):p34arc(ha):E-cadherin(h) (binding) | E-cadherin(h) + ATP --> E-cadherin(h){pY} + ADP (phosphorylation) | E-cadherin(h) --> E-cadherin-p29(h) + protein remnants (cleavage) | E-cadherin(h) --> E-cadherin-p24(h) + protein remnants (cleavage) | NPRAPa(m) + ABP-S(r) + E-cadherin(h) <==> NPRAPa(m):ABP-S(r):E-cadherin(h) (binding) | E-cadherin(h) + Smad7(m.s.) <==> E-cadherin(h):Smad7(m.s.) (binding) | E-cadherin(h) + DDB1(h) <==> E-cadherin(h):DDB1(h) (binding) | E-cadherin(h) --/ Skp2(h) (decrease of abundance) | CDH1(h) --> E-cadherin(h) (expression). | EGF(m.s.) --/ E-cadherin(h) (decrease of abundance) | Smad7(m.s.) --> E-cadherin(h) (increase of abundance) | calcitriol --> E-cadherin(h) (increase of abundance) | insulin(m.s.) --> E-cadherin(h) (increase of abundance) | p53(h) --> E-cadherin(h) (increase of abundance) | slug(m) --/ E-cadherin(h) (decrease of abundance) | Chfr(h) --> E-cadherin(h) (increase of abundance) | slc7a11(h) --/ E-cadherin(h) (decrease of abundance) | E-cadherin(h) --Mdc15(m.s.)--> E-cadherin-ECD(h) + protein remnants (cleavage) | E-cadherin(h) + DDB1(m.s.) <==> E-cadherin(h):DDB1(m.s.) (binding) | DDB1(h) + E-cadherin(h) <==> DDB1(h):E-cadherin(h) (binding) | E-cadherin(h) --/ Geminin(h) (decrease of abundance) | CDH1(h) --> E-cadherin(h) (expression). | CDH1(h) --> E-cadherin(h) (expression). | hsa-miR-373 --> E-cadherin(h) (activation). |
|---|
Post Transcriptional Modification From dbPTM | | Top | |
|
Location (AA) |
PTM type |
Literature |
Database |
558 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 637 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 838 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 840 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 846 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
|---|
Methylation Profile From DiseaseMeth database | | Top | |
|
Chromosome |
Location |
Source |
|---|---|---|
chr16 |
Promoter: 67327196 - 67329196 | Agilent_014791 |
chr16 |
Promoter: 67327196 - 67329196 | GoldenGate_Methylation_Cancer_Panel_I |
chr16 |
Promoter: 67327196 - 67329196 | GSE27584 |
chr16 |
Promoter: 67327196 - 67329196 | Agilent_014791_44K |
chr16 |
Promoter: 67327196 - 67329196 | PMID:17348438 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:20568901 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:21455633 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:21775555 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:20064646 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11496321 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12448005 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12210063 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12695555 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16830381 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12692837 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14998854 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14556664 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12746473 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11413518 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16219136 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:10749913 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12763209 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14750169 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16108828 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16531765 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12776596 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16475210 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14507661 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:10495421 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12631658 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12163364 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:17369979 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16163424 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:17139167 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15942635 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12060614 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11313896 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15313375 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14675710 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16598757 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15254707 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11196170 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12841866 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15042681 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16644104 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14714493 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15201980 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12467239 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11895880 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15639718 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15073103 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15758578 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15495254 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16732935 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15863205 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12899712 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11106238 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15198948 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16192589 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12082624 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16343268 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12660822 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12937151 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:17121887 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11297254 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15911243 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16613325 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14507645 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16565510 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15831995 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15467712 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12213730 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15122305 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15389252 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14719065 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12397640 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12824891 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:17276933 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11171827 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15476557 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16512896 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15788661 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15328171 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16495925 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15172987 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15543763 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12163387 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12942643 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12800196 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14534701 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15589597 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16331610 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11448914 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16803511 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12751384 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12773202 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15713962 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11549575 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12124340 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12203370 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16849682 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11839665 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15154012 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16242928 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16639696 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15036650 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11458121 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15289848 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11839671 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16170165 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:17363525 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:17139617 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11753952 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16483154 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15361301 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12767073 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12553040 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12839684 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15073117 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12632081 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12751385 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12760799 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15029256 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:17206475 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16688669 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15367334 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16353169 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:17272309 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11568972 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15217927 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15289362 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12559313 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14555992 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11477576 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12672028 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:9458351 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14985090 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11900224 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16449996 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:17034532 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16494996 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14559984 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15596045 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16303245 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12429618 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14970867 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16061849 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:10766168 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12584167 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16596173 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:14501508 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15272533 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15870861 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:11578811 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15447999 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15471559 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:16699861 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15915369 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15197802 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15109538 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15318245 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15173091 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12082610 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12569599 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12896902 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15999364 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15662588 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15840741 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:12874790 |
chr16 |
Promoter: 67327196 - 67329196 | PMID:15507671 |