Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10017570HBVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30010694HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052490HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052491HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052492HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052493HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052494HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TCGA Plot Options
Drug Information
GeneHTR2B
DrugBank IDDB00696
Drug NameErgotamine
Target IDBE0000393
UniProt IDP41595
Regulation Type
PubMed IDs11104741
CitationsRothman RB, Baumann MH, Savage JE, Rauser L, McBride A, Hufeisen SJ, Roth BL: Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications. Circulation. 2000 Dec 5;102(23):2836-41.
GroupsApproved
Direct ClassificationErgotamines, dihydroergotamines, and derivatives
SMILES[H][C@@]12CCCN1C(=O)[C@H](CC1=CC=CC=C1)N1C(=O)[C@](C)(NC(=O)[C@H]3CN(C)[C@]4([H])CC5=CNC6=CC=CC(=C56)C4=C3)O[C@@]21O
Pathways
PharmGKBPA164747651
ChEMBLCHEMBL442