Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10017570HBVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30010694HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052490HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052491HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052492HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052493HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052494HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TCGA Plot Options
Drug Information
GeneHTR2B
DrugBank IDDB01392
Drug NameYohimbine
Target IDBE0000393
UniProt IDP41595
Regulation Typeantagonist
PubMed IDs8032658; 9225287
CitationsBaxter GS, Murphy OE, Blackburn TP: Further characterization of 5-hydroxytryptamine receptors (putative 5-HT2B) in rat stomach fundus longitudinal muscle. Br J Pharmacol. 1994 May;112(1):323-31.@@Bonhaus DW, Weinhardt KK, Taylor M, DeSouza A, McNeeley PM, Szczepanski K, Fontana DJ, Trinh J, Rocha CL, Dawson MW, Flippin LA, Eglen RM: RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist. Neuropharmacology. 1997 Apr-May;36(4-5):621-9.
GroupsApproved; Investigational; Vet_approved
Direct ClassificationYohimbine alkaloids
SMILES[H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2
Pathways
PharmGKBPA451946
ChEMBLCHEMBL15245