Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10017570HBVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30010694HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052490HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052491HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052492HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052493HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
TVIS30052494HIVENSG00000135914.6protein_codingHTR2BNoNo3357P41595
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Drug Information
GeneHTR2B
DrugBank IDDB01242
Drug NameClomipramine
Target IDBE0000393
UniProt IDP41595
Regulation Typeantagonist
PubMed IDs9862411; 14501155; 1296670
CitationsSargent PA, Quested DJ, Cowen PJ: Clomipramine enhances the cortisol response to 5-HTP: implications for the therapeutic role of 5-HT2 receptors. Psychopharmacology (Berl). 1998 Nov;140(1):120-2.@@Sugimoto Y, Inoue K, Yamada J: The tricyclic antidepressant clomipramine increases plasma glucose levels of mice. J Pharmacol Sci. 2003 Sep;93(1):74-9.@@Contreras CM, Marvan ML, Munoz-Mendez A, Ramirez-Morales A: Cortical and septal responses to dorsal raphe nucleus stimulation in the rat: long-term clomipramine actions. Bol Estud Med Biol. 1992 Jan-Dec;40(1-4):3-7.
GroupsApproved; Investigational; Vet_approved
Direct ClassificationDibenzazepines
SMILESCN(C)CCCN1C2=CC=CC=C2CCC2=C1C=C(Cl)C=C2
PathwaysClomipramine Metabolism Pathway
PharmGKBPA449048
ChEMBLCHEMBL415