| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017570 | HBV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30010694 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30052490 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30052491 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30052492 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30052493 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30052494 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR2B |
|---|---|
| DrugBank ID | DB00805 |
| Drug Name | Minaprine |
| Target ID | BE0000393 |
| UniProt ID | P41595 |
| Regulation Type | antagonist |
| PubMed IDs | 17139284; 17016423; 1361012; 2975224; 11752352 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Kodama K, Shibata S, Ueki S: Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia. Jpn J Pharmacol. 1992 Sep;60(1):33-8.@@Muramatsu M, Tamaki-Ohashi J, Usuki C, Araki H, Chaki S, Aihara H: 5-HT2 antagonists and minaprine block the 5-HT-induced inhibition of dopamine release from rat brain striatal slices. Eur J Pharmacol. 1988 Aug 9;153(1):89-95.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Phenylpyridazines |
| SMILES | CC1=CC(=NN=C1NCCN1CCOCC1)C1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA164748351 |
| ChEMBL | CHEMBL278819 |
