| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017570 | HBV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30010694 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30052490 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30052491 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30052492 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30052493 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
| TVIS30052494 | HIV | ENSG00000135914.6 | protein_coding | HTR2B | No | No | 3357 | P41595 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR2B |
|---|---|
| DrugBank ID | DB05607 |
| Drug Name | PRX-08066 |
| Target ID | BE0000393 |
| UniProt ID | P41595 |
| Regulation Type | antagonist |
| PubMed IDs | 20430844 |
| Citations | Porvasnik SL, Germain S, Embury J, Gannon KS, Jacques V, Murray J, Byrne BJ, Shacham S, Al-Mousily F: PRX-08066, a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. J Pharmacol Exp Ther. 2010 Aug;334(2):364-72. doi: 10.1124/jpet.109.165001. Epub 2010 Apr 29. |
| Groups | Investigational |
| Direct Classification | N-benzylpiperidines |
| SMILES | OC(=O)C=CC(O)=O.FC1=C(C=C(CN2CCC(CC2)NC2=C3C=C(Cl)SC3=NC=N2)C=C1)C#N |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL4297322 |
