| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44045428 | HTLV-1 | ENSG00000091831.25 | protein_coding | ESR1 | Yes | No | 2099 | A0A125SXW3 G4XH65 H0Y4W6 P03372 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ESR1 |
|---|---|
| DrugBank ID | DB00624 |
| Drug Name | Testosterone |
| Target ID | BE0000123 |
| UniProt ID | P03372 |
| Regulation Type | inhibitor |
| PubMed IDs | 12676605; 10973921 |
| Citations | Kojima H, Iida M, Katsura E, Kanetoshi A, Hori Y, Kobayashi K: Effects of a diphenyl ether-type herbicide, chlornitrofen, and its amino derivative on androgen and estrogen receptor activities. Environ Health Perspect. 2003 Apr;111(4):497-502.@@Zhou J, Ng S, Adesanya-Famuiya O, Anderson K, Bondy CA: Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression. FASEB J. 2000 Sep;14(12):1725-30. doi: 10.1096/fj.99-0863com. |
| Groups | Approved; Investigational |
| Direct Classification | Androgens and derivatives |
| SMILES | [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C |
| Pathways | Aromatase Deficiency; Androgen and Estrogen Metabolism; 17-beta Hydroxysteroid Dehydrogenase III Deficiency; Androstenedione Metabolism |
| PharmGKB | PA451627 |
| ChEMBL | CHEMBL386630 |
