Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10004783HBVENSG00000116329.12protein_codingOPRD1NoNo4985P41143
TVIS30074531HIVENSG00000116329.12protein_codingOPRD1NoNo4985P41143
TVIS30022908HIVENSG00000116329.12protein_codingOPRD1NoNo4985P41143
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Drug Information
GeneOPRD1
DrugBank IDDB00844
Drug NameNalbuphine
Target IDBE0000420
UniProt IDP41143
Regulation Typeantagonist
PubMed IDs8093631; 2826773; 11752352
CitationsChen JC, Smith ER, Cahill M, Cohen R, Fishman JB: The opioid receptor binding of dezocine, morphine, fentanyl, butorphanol and nalbuphine. Life Sci. 1993;52(4):389-96.@@De Souza EB, Schmidt WK, Kuhar MJ: Nalbuphine: an autoradiographic opioid receptor binding profile in the central nervous system of an agonist/antagonist analgesic. J Pharmacol Exp Ther. 1988 Jan;244(1):391-402.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.
GroupsApproved
Direct ClassificationPhenanthrenes and derivatives
SMILESO[C@H]1CC[C@@]2(O)[C@H]3CC4=CC=C(O)C5=C4[C@@]2(CCN3CC2CCC2)[C@H]1O5
PathwaysNalbuphine Action Pathway
PharmGKBPA164745372
ChEMBLCHEMBL895