| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10004783 | HBV | ENSG00000116329.12 | protein_coding | OPRD1 | No | No | 4985 | P41143 |
| TVIS30074531 | HIV | ENSG00000116329.12 | protein_coding | OPRD1 | No | No | 4985 | P41143 |
| TVIS30022908 | HIV | ENSG00000116329.12 | protein_coding | OPRD1 | No | No | 4985 | P41143 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | OPRD1 |
|---|---|
| DrugBank ID | DB01548 |
| Drug Name | Diprenorphine |
| Target ID | BE0000420 |
| UniProt ID | P41143 |
| Regulation Type | antagonist |
| PubMed IDs | 10319982; 10413036; 11526449; 12672796; 12909189; 20641600 |
| Citations | Willoch F, Tolle TR, Wester HJ, Munz F, Petzold A, Schwaiger M, Conrad B, Bartenstein P: Central pain after pontine infarction is associated with changes in opioid receptor binding: a PET study with 11C-diprenorphine. AJNR Am J Neuroradiol. 1999 Apr;20(4):686-90.@@Jones AK, Kitchen ND, Watabe H, Cunningham VJ, Jones T, Luthra SK, Thomas DG: Measurement of changes in opioid receptor binding in vivo during trigeminal neuralgic pain using [11C] diprenorphine and positron emission tomography. J Cereb Blood Flow Metab. 1999 Jul;19(7):803-8.@@Kampa M, Hatzoglou A, Notas G, Niniraki M, Kouroumalis E, Castanas E: Opioids are non-competitive inhibitors of nitric oxide synthase in T47D human breast cancer cells. Cell Death Differ. 2001 Sep;8(9):943-52.@@Marie N, Lecoq I, Jauzac P, Allouche S: Differential sorting of human delta-opioid receptors after internalization by peptide and alkaloid agonists. J Biol Chem. 2003 Jun 20;278(25):22795-804. Epub 2003 Apr 2.@@Webster JM, Bentley MT, Wojcikiewicz RJ: N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits ligand binding to certain G protein-coupled receptors. Eur J Pharmacol. 2003 Aug 1;474(1):1-5.@@Leung K: [6-O-methyl-11C]Diprenorphine . |
| Groups | Illicit; Vet_approved |
| Direct Classification | Phenanthrenes and derivatives |
| SMILES | [H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(CC3CC3)[C@]([H])(C4)[C@]11CC[C@@]2(OC)[C@H](C1)C(C)(C)O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL281786 |
