| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10004783 | HBV | ENSG00000116329.12 | protein_coding | OPRD1 | No | No | 4985 | P41143 |
| TVIS30074531 | HIV | ENSG00000116329.12 | protein_coding | OPRD1 | No | No | 4985 | P41143 |
| TVIS30022908 | HIV | ENSG00000116329.12 | protein_coding | OPRD1 | No | No | 4985 | P41143 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | OPRD1 |
|---|---|
| DrugBank ID | DB06274 |
| Drug Name | Alvimopan |
| Target ID | BE0000420 |
| UniProt ID | P41143 |
| Regulation Type | antagonist |
| PubMed IDs | 15882122; 17340127 |
| Citations | Neary P, Delaney CP: Alvimopan. Expert Opin Investig Drugs. 2005 Apr;14(4):479-88.@@Beattie DT, Cheruvu M, Mai N, O'Keefe M, Johnson-Rabidoux S, Peterson C, Kaufman E, Vickery R: The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone. Naunyn Schmiedebergs Arch Pharmacol. 2007 May;375(3):205-20. Epub 2007 Mar 6. |
| Groups | Approved; Investigational |
| Direct Classification | Hybrid peptides |
| SMILES | C[C@H]1CN(C[C@H](CC2=CC=CC=C2)C(=O)NCC(O)=O)CC[C@@]1(C)C1=CC(O)=CC=C1 |
| Pathways | Alvimopan Action Pathway |
| PharmGKB | PA164754864 |
| ChEMBL | CHEMBL270190 |
