Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10004783HBVENSG00000116329.12protein_codingOPRD1NoNo4985P41143
TVIS30074531HIVENSG00000116329.12protein_codingOPRD1NoNo4985P41143
TVIS30022908HIVENSG00000116329.12protein_codingOPRD1NoNo4985P41143
TCGA Plot Options
Drug Information
GeneOPRD1
DrugBank IDDB09272
Drug NameEluxadoline
Target IDBE0000420
UniProt IDP41143
Regulation Typeantagonist
PubMed IDs25261794
CitationsFujita W, Gomes I, Dove LS, Prohaska D, McIntyre G, Devi LA: Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers. Biochem Pharmacol. 2014 Dec 1;92(3):448-56. doi: 10.1016/j.bcp.2014.09.015. Epub 2014 Sep 28.
GroupsApproved; Investigational
Direct ClassificationPhenylalanine and derivatives
SMILESCOC1=CC=C(CN([C@@H](C)C2=NC(=CN2)C2=CC=CC=C2)C(=O)[C@@H](N)CC2=C(C)C=C(C=C2C)C(N)=O)C=C1C(O)=O
Pathways
PharmGKB
ChEMBLCHEMBL2159122