Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10004783HBVENSG00000116329.12protein_codingOPRD1NoNo4985P41143
TVIS30074531HIVENSG00000116329.12protein_codingOPRD1NoNo4985P41143
TVIS30022908HIVENSG00000116329.12protein_codingOPRD1NoNo4985P41143
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Drug Information
GeneOPRD1
DrugBank IDDB01192
Drug NameOxymorphone
Target IDBE0000420
UniProt IDP41143
Regulation Typeantagonist
PubMed IDs17595308; 14998329
CitationsChamberlin KW, Cottle M, Neville R, Tan J: Oral oxymorphone for pain management. Ann Pharmacother. 2007 Jul;41(7):1144-52. Epub 2007 Jun 26.@@Ananthan S, Khare NK, Saini SK, Seitz LE, Bartlett JL, Davis P, Dersch CM, Porreca F, Rothman RB, Bilsky EJ: Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone]. J Med Chem. 2004 Mar 11;47(6):1400-12.
GroupsApproved; Investigational; Vet_approved
Direct ClassificationPhenanthrenes and derivatives
SMILES[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1(O)CCC2=O
PathwaysOxymorphone Action Pathway
PharmGKBPA450748
ChEMBLCHEMBL963